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The map label for this gene is metI [H]

Identifier: 220904809

GI number: 220904809

Start: 1843261

End: 1843968

Strand: Direct

Name: metI [H]

Synonym: Ddes_1541

Alternate gene names: 220904809

Gene position: 1843261-1843968 (Clockwise)

Preceding gene: 220904808

Following gene: 220904810

Centisome position: 64.15

GC content: 54.94

Gene sequence:

>708_bases
ATGAGTGATCAACTGAGCACCCTCGCCCAACTGGCCCAGGACATGCACCCCTTGTGGGAACGCTTGCAGGACAAAATGCC
GGAAATTCTCATGGCCACCTGGGAAACCGTGCAGATGGTGCTGATTTCGACCTTTTTTTCTCTGGTTATCGGCTTCATGC
TGGCAATCCTGATGATCGTGACCAATCCCATCGGCCTGAAACCCTGCCGTTCGGTCTACAGAATAGTGGACTTTGTGGTG
AACCTTCTGCGTTCGTTCCCGTTCATCATTCTGCTGATCGCCATCATACCCTTTACGCGCATGGTGGTAGGCACCTCTAT
CGGCAGCGGGGCGGCCATTGTGCCTCTTACCATTGCGGCGGCCCCCTTTGTGGCACGGCTTATCGAAACCTGCTTTCTTG
AGGTGGACAGGGGCGTTATCGAGGCGGCCCGGTCGTTTGGGGCCAGCAATGCCCAGATCATTTTCCGGGTGCTTTTTCCC
GAAGCCCTGCCTTCCATCGTGCTCAACATCGCGGTCATCGCCATTACCCTGCTCGGTTACTCTGCCATGGCGGGAACCGT
AGGCGGTGGCGGCCTGGGCGACCTGGCCGTCAAATACGGCTACAACCGCTTTCAGGTTGATATCATGGTCTATTCCGTTA
TCATCCTGTGTGTGCTGGTGCTGCTTATCCAGAGCATCTGCAACTTTTTGTACAAAATTCTGCGATAA

Upstream 100 bases:

>100_bases
CAGGACCAGAATATTGACGCCGTGCTGCGCTACCTGAAGGAGCAGCGCCTGTACTGGGAGATACTGGAATATCCTTTGCA
ACAAGCTACGGATGCCGCCA

Downstream 100 bases:

>100_bases
AGCCCGCTGCGCGCGCAACGGGCTTTTGTCCCTCTTCAACGGCACAGTCTTACCCGCACAAGGAGCCATCATGAAACGCC
TGCTTCTGTCCCTGGTCATG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSDQLSTLAQLAQDMHPLWERLQDKMPEILMATWETVQMVLISTFFSLVIGFMLAILMIVTNPIGLKPCRSVYRIVDFVV
NLLRSFPFIILLIAIIPFTRMVVGTSIGSGAAIVPLTIAAAPFVARLIETCFLEVDRGVIEAARSFGASNAQIIFRVLFP
EALPSIVLNIAVIAITLLGYSAMAGTVGGGGLGDLAVKYGYNRFQVDIMVYSVIILCVLVLLIQSICNFLYKILR

Sequences:

>Translated_235_residues
MSDQLSTLAQLAQDMHPLWERLQDKMPEILMATWETVQMVLISTFFSLVIGFMLAILMIVTNPIGLKPCRSVYRIVDFVV
NLLRSFPFIILLIAIIPFTRMVVGTSIGSGAAIVPLTIAAAPFVARLIETCFLEVDRGVIEAARSFGASNAQIIFRVLFP
EALPSIVLNIAVIAITLLGYSAMAGTVGGGGLGDLAVKYGYNRFQVDIMVYSVIILCVLVLLIQSICNFLYKILR
>Mature_234_residues
SDQLSTLAQLAQDMHPLWERLQDKMPEILMATWETVQMVLISTFFSLVIGFMLAILMIVTNPIGLKPCRSVYRIVDFVVN
LLRSFPFIILLIAIIPFTRMVVGTSIGSGAAIVPLTIAAAPFVARLIETCFLEVDRGVIEAARSFGASNAQIIFRVLFPE
ALPSIVLNIAVIAITLLGYSAMAGTVGGGGLGDLAVKYGYNRFQVDIMVYSVIILCVLVLLIQSICNFLYKILR

Specific function: Part of the binding-protein-dependent transport system for D-methionine. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG2011

COG function: function code P; ABC-type metal ion transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786397, Length=176, Percent_Identity=51.1363636363636, Blast_Score=157, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25762; Mature: 25630

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS00065 D_2_HYDROXYACID_DH_1 ; PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQLSTLAQLAQDMHPLWERLQDKMPEILMATWETVQMVLISTFFSLVIGFMLAILMIV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNPIGLKPCRSVYRIVDFVVNLLRSFPFIILLIAIIPFTRMVVGTSIGSGAAIVPLTIAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
APFVARLIETCFLEVDRGVIEAARSFGASNAQIIFRVLFPEALPSIVLNIAVIAITLLGY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAMAGTVGGGGLGDLAVKYGYNRFQVDIMVYSVIILCVLVLLIQSICNFLYKILR
HHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SDQLSTLAQLAQDMHPLWERLQDKMPEILMATWETVQMVLISTFFSLVIGFMLAILMIV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNPIGLKPCRSVYRIVDFVVNLLRSFPFIILLIAIIPFTRMVVGTSIGSGAAIVPLTIAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
APFVARLIETCFLEVDRGVIEAARSFGASNAQIIFRVLFPEALPSIVLNIAVIAITLLGY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAMAGTVGGGGLGDLAVKYGYNRFQVDIMVYSVIILCVLVLLIQSICNFLYKILR
HHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]