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The map label for this gene is tolQ [H]

Identifier: 220904727

GI number: 220904727

Start: 1747561

End: 1748250

Strand: Direct

Name: tolQ [H]

Synonym: Ddes_1459

Alternate gene names: 220904727

Gene position: 1747561-1748250 (Clockwise)

Preceding gene: 220904725

Following gene: 220904728

Centisome position: 60.82

GC content: 58.84

Gene sequence:

>690_bases
ATGAATTCCATGATTGAGGCTGTGCTGCAGGCTACGCTTATTTCCAAATGTGTGCTGGTACTGCTGTTGTTTATGTCTGT
GTCCAGTTGGGCGTACATGTGCGGAAAGTGGTTGACCTTGCGCTCTGCCCAGCGCCGTACCCAAAGAGGGCTTGTGGCCT
TTGACGATGCCGGAGAGTTGTGCCAGGCCCTGCCTGTAATGGAGGCTGACCGCCAGTCGCCCCTGTACGGCATCACCCGC
CGCGCTGTGCGCGAGTACAACCGCCTCACCCGCACGGGAGATACCGAGCGCCTGCTTAATGACAACGTGCGCCGTGCCCT
GCATTTCGCCATTGCCGAAGAAGTCGCACGGCTCAAGTCCTCTCTGGCCCTGCTCGCCACCGCCGCCAATACGGCCCCGT
TCATCGGCCTGTTCGGCACAGTGTGGGGAATCATGCATTCCTTTACTGCCATTGCCCAGATGAAGAGCGTGTCGCTGGCA
ACAGTGGCCCCCGGCATAGCTGAAGCGCTTATTGCCACGGCAGTGGGCCTGTTTGTGGCTATTCCCGCCGTGTGCGGCTA
CAACGTGTTCAGGGCAAAGCTGGTATATATTGAAGGCGTGTGCATCAACTACGCCGGTCAGCTGCTCAACCGCCTGCAAC
ATGAAGCGCCGGAATACAGCAAAGGCATCAACTTTGCCGGGGAGCGCTGA

Upstream 100 bases:

>100_bases
TTTTCATAACCTATATCTTATATTGACATGATGCTGCGGACTGACTATGTATATACAGCACTTTGAATTTCAATTTCATA
TTCATATGGAGAGAGGCCGG

Downstream 100 bases:

>100_bases
GTATGGCCTCATCCGCTGATGACGATTTTGTTGCCGACATCAACGTAACCCCATTTGTGGACGTCATGCTGGTATTGCTG
ATCATTTTTATGGTCACGGC

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MNSMIEAVLQATLISKCVLVLLLFMSVSSWAYMCGKWLTLRSAQRRTQRGLVAFDDAGELCQALPVMEADRQSPLYGITR
RAVREYNRLTRTGDTERLLNDNVRRALHFAIAEEVARLKSSLALLATAANTAPFIGLFGTVWGIMHSFTAIAQMKSVSLA
TVAPGIAEALIATAVGLFVAIPAVCGYNVFRAKLVYIEGVCINYAGQLLNRLQHEAPEYSKGINFAGER

Sequences:

>Translated_229_residues
MNSMIEAVLQATLISKCVLVLLLFMSVSSWAYMCGKWLTLRSAQRRTQRGLVAFDDAGELCQALPVMEADRQSPLYGITR
RAVREYNRLTRTGDTERLLNDNVRRALHFAIAEEVARLKSSLALLATAANTAPFIGLFGTVWGIMHSFTAIAQMKSVSLA
TVAPGIAEALIATAVGLFVAIPAVCGYNVFRAKLVYIEGVCINYAGQLLNRLQHEAPEYSKGINFAGER
>Mature_229_residues
MNSMIEAVLQATLISKCVLVLLLFMSVSSWAYMCGKWLTLRSAQRRTQRGLVAFDDAGELCQALPVMEADRQSPLYGITR
RAVREYNRLTRTGDTERLLNDNVRRALHFAIAEEVARLKSSLALLATAANTAPFIGLFGTVWGIMHSFTAIAQMKSVSLA
TVAPGIAEALIATAVGLFVAIPAVCGYNVFRAKLVYIEGVCINYAGQLLNRLQHEAPEYSKGINFAGER

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=227, Percent_Identity=33.4801762114537, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1789381, Length=205, Percent_Identity=36.0975609756098, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 25074; Mature: 25074

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSMIEAVLQATLISKCVLVLLLFMSVSSWAYMCGKWLTLRSAQRRTQRGLVAFDDAGEL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHH
CQALPVMEADRQSPLYGITRRAVREYNRLTRTGDTERLLNDNVRRALHFAIAEEVARLKS
HHHCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLALLATAANTAPFIGLFGTVWGIMHSFTAIAQMKSVSLATVAPGIAEALIATAVGLFVA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
IPAVCGYNVFRAKLVYIEGVCINYAGQLLNRLQHEAPEYSKGINFAGER
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCC
>Mature Secondary Structure
MNSMIEAVLQATLISKCVLVLLLFMSVSSWAYMCGKWLTLRSAQRRTQRGLVAFDDAGEL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHH
CQALPVMEADRQSPLYGITRRAVREYNRLTRTGDTERLLNDNVRRALHFAIAEEVARLKS
HHHCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLALLATAANTAPFIGLFGTVWGIMHSFTAIAQMKSVSLATVAPGIAEALIATAVGLFVA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
IPAVCGYNVFRAKLVYIEGVCINYAGQLLNRLQHEAPEYSKGINFAGER
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]