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The map label for this gene is mraY

Identifier: 220904381

GI number: 220904381

Start: 1303376

End: 1304452

Strand: Direct

Name: mraY

Synonym: Ddes_1110

Alternate gene names: 220904381

Gene position: 1303376-1304452 (Clockwise)

Preceding gene: 220904380

Following gene: 220904382

Centisome position: 45.36

GC content: 53.3

Gene sequence:

>1077_bases
ATGTTCTACAATTTCCTTTCTCCTCTCGCATCGGAATGGACATTCTTTAACGTCTTCCGCTACATCACCTTCCGTTCCAT
GGCGGCGCTCATGACGGCTCTGCTCATTTCCATAATTCTCGGGCCGCGGTTTATTACATGGCTGCGCAGGTTGAAGTGCG
GCCAGTATATCCATGAGGACGTGGCGGCCCACGCCTGCAAAGCCGGAACTCCCACCATGGGCGGCCTGCTGATGCTGTTC
AGCCTTTCGGTAAGCCTGCTTTTATGGGCAGATCTGACAAATATTTACATCTGGCAGGCTTTTTTTGTTTTTGCCGGATT
CGGGGCGGTGGGTTTTTGGGATGATATTACCAAGCTGCGCCATCATAAAAACCGGGGTATTTCCGGCAAGGCCAAGATGG
GCGGCCAGCTTGCCGTGGCCTGCGTGGCCATGCTGCTGCTTTTTGTTAATCCTGACTACAGCAGCAAGCTTACCATTCCC
TTTTTTAAAGAAGTTACTTTTGATCTGGGCTGGTTTTATCTGCCGTTCGGCGTTTTTGTCATGGTGGCGGCGTCCAATGC
CGTCAATCTTACGGACGGTCTTGACGGCCTTGCCATAGGTCCTTCCATTGTTGCCTGCATTGTTTTTTCCATTTTTATCT
ATATTACGGGCAACGCGCGCTTTGCGGGGTATCTGCTGGTTCCCTATATGCCCGGCGTGGGTGAGGTTACCATTTTTTGC
GCTGCCCTTGTGGGCGCGGGGTTGGGTTTCTTATGGTTTAACGCCTATCCGGCTCAGGTCTTCATGGGGGATGTGGGATC
CCTGTCCATCGGTGGAGTGCTTGGTTACCTTGCCCTGCTGTGCAAGCAGGAGCTGGTGCTTGCTGTGGTAGGCGGCCTTT
TTGTGGCCGAAACGCTTTCTGTGATCGTGCAGGTGGGGTACTTCCGCTGGACCGGGGGCAAGCGTTTCTTCCGTATGGCG
CCCCTGCACCATCATTTTGAACTCAAAGGCGTGCCAGAGTCCAAAATCATCATCCGCTTCTGGATCACGTCAATTCTGCT
TGGCCTCATGGCGCTTTCAGTCCTGAAGCTGCGCTGA

Upstream 100 bases:

>100_bases
CATCACCAATTCCCGCAGATCTACGGGAGATCTACCCAGGGCCTTGCCTGGCCCGCTGACAGTAACGGTCGCAGAGTGGC
CAAACGAACGGACTCCGTGC

Downstream 100 bases:

>100_bases
GGAGATATGGTATGGCATTGGAAAAAACGCGCGGCAGACGCATTAGCGTTGGCGAAACGGCAGTGGTGGTGGGGGCGGGG
CGTTCCGGCCTTGCCGCTGC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MFYNFLSPLASEWTFFNVFRYITFRSMAALMTALLISIILGPRFITWLRRLKCGQYIHEDVAAHACKAGTPTMGGLLMLF
SLSVSLLLWADLTNIYIWQAFFVFAGFGAVGFWDDITKLRHHKNRGISGKAKMGGQLAVACVAMLLLFVNPDYSSKLTIP
FFKEVTFDLGWFYLPFGVFVMVAASNAVNLTDGLDGLAIGPSIVACIVFSIFIYITGNARFAGYLLVPYMPGVGEVTIFC
AALVGAGLGFLWFNAYPAQVFMGDVGSLSIGGVLGYLALLCKQELVLAVVGGLFVAETLSVIVQVGYFRWTGGKRFFRMA
PLHHHFELKGVPESKIIIRFWITSILLGLMALSVLKLR

Sequences:

>Translated_358_residues
MFYNFLSPLASEWTFFNVFRYITFRSMAALMTALLISIILGPRFITWLRRLKCGQYIHEDVAAHACKAGTPTMGGLLMLF
SLSVSLLLWADLTNIYIWQAFFVFAGFGAVGFWDDITKLRHHKNRGISGKAKMGGQLAVACVAMLLLFVNPDYSSKLTIP
FFKEVTFDLGWFYLPFGVFVMVAASNAVNLTDGLDGLAIGPSIVACIVFSIFIYITGNARFAGYLLVPYMPGVGEVTIFC
AALVGAGLGFLWFNAYPAQVFMGDVGSLSIGGVLGYLALLCKQELVLAVVGGLFVAETLSVIVQVGYFRWTGGKRFFRMA
PLHHHFELKGVPESKIIIRFWITSILLGLMALSVLKLR
>Mature_358_residues
MFYNFLSPLASEWTFFNVFRYITFRSMAALMTALLISIILGPRFITWLRRLKCGQYIHEDVAAHACKAGTPTMGGLLMLF
SLSVSLLLWADLTNIYIWQAFFVFAGFGAVGFWDDITKLRHHKNRGISGKAKMGGQLAVACVAMLLLFVNPDYSSKLTIP
FFKEVTFDLGWFYLPFGVFVMVAASNAVNLTDGLDGLAIGPSIVACIVFSIFIYITGNARFAGYLLVPYMPGVGEVTIFC
AALVGAGLGFLWFNAYPAQVFMGDVGSLSIGGVLGYLALLCKQELVLAVVGGLFVAETLSVIVQVGYFRWTGGKRFFRMA
PLHHHFELKGVPESKIIIRFWITSILLGLMALSVLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=353, Percent_Identity=49.5750708215297, Blast_Score=328, Evalue=4e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_DESDA (B8IZT8)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002479693.1
- GeneID:   7284792
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_1110
- HOGENOM:   HBG708263
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 39508; Mature: 39508

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x252590a8)-; HASH(0x271bc5f4)-; HASH(0x272fd6c8)-; HASH(0x40513768)-; HASH(0x2502f674)-; HASH(0x405138e8)-; HASH(0x2744a9f0)-; HASH(0x2705741c)-; HASH(0x40513ec4)-; HASH(0x26ac1898)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYNFLSPLASEWTFFNVFRYITFRSMAALMTALLISIILGPRFITWLRRLKCGQYIHED
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAAHACKAGTPTMGGLLMLFSLSVSLLLWADLTNIYIWQAFFVFAGFGAVGFWDDITKLR
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
HHKNRGISGKAKMGGQLAVACVAMLLLFVNPDYSSKLTIPFFKEVTFDLGWFYLPFGVFV
HHHCCCCCCCHHCCCHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHH
MVAASNAVNLTDGLDGLAIGPSIVACIVFSIFIYITGNARFAGYLLVPYMPGVGEVTIFC
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHH
AALVGAGLGFLWFNAYPAQVFMGDVGSLSIGGVLGYLALLCKQELVLAVVGGLFVAETLS
HHHHHCCHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIVQVGYFRWTGGKRFFRMAPLHHHFELKGVPESKIIIRFWITSILLGLMALSVLKLR
HHHHHHCEEECCCCCEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MFYNFLSPLASEWTFFNVFRYITFRSMAALMTALLISIILGPRFITWLRRLKCGQYIHED
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAAHACKAGTPTMGGLLMLFSLSVSLLLWADLTNIYIWQAFFVFAGFGAVGFWDDITKLR
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
HHKNRGISGKAKMGGQLAVACVAMLLLFVNPDYSSKLTIPFFKEVTFDLGWFYLPFGVFV
HHHCCCCCCCHHCCCHHHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHH
MVAASNAVNLTDGLDGLAIGPSIVACIVFSIFIYITGNARFAGYLLVPYMPGVGEVTIFC
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHH
AALVGAGLGFLWFNAYPAQVFMGDVGSLSIGGVLGYLALLCKQELVLAVVGGLFVAETLS
HHHHHCCHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIVQVGYFRWTGGKRFFRMAPLHHHFELKGVPESKIIIRFWITSILLGLMALSVLKLR
HHHHHHCEEECCCCCEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA