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The map label for this gene is panD

Identifier: 220904255

GI number: 220904255

Start: 1148739

End: 1149164

Strand: Direct

Name: panD

Synonym: Ddes_0982

Alternate gene names: 220904255

Gene position: 1148739-1149164 (Clockwise)

Preceding gene: 220904254

Following gene: 220904269

Centisome position: 39.98

GC content: 53.29

Gene sequence:

>426_bases
ATGCTGAAGATTTTACGCGCCAAATTGCACGGCATACGCGTAACGGAGTGTGTGCTGGACTATCACGGCTCTATCACCCT
TGATCCGGAAATATGCGGGCTGGCAGGTATCATGCCGCTGGAGTTCGTTTATATCTGGAACAAACACAGCGGGCAGCGTA
TTTCCACCTACGTCATTTACGGCGAGGCCGGGTCGCGCTGCTGCATTCTCAACGGAGCGGCCGCGCGCACATGCCAGAAA
GGGGATGAAGTTATCATCAGCGCTTTTGAGTATGTCGCCGGACCGGGGGATATTTCTCAACGCAGCCCGGTTGTTTTGAC
TTTTGACGCTCACAACAGGGTGCAGGAACGTTTACGTTATATAGTGGAACAGAAGGATGGCGGCATGTCTTTCAATATTG
CCGATGATCCCCTGCCGGAGGCATGA

Upstream 100 bases:

>100_bases
AGCCAAAGGTGTTTGCAGGTTGTGCGATGCTCGCCTGCAAAAGCAGCCCGCGCGGGGGCGGCAGCCTGTTTGTGCGGCAT
GTTTTGAAAGAGAGAGAAAA

Downstream 100 bases:

>100_bases
CCTGCCACCGCTGAAAGCATATAACAAAAGGCCCGGTATATCCGGGCCTTTTGTTATATGGAGTCTGTCACGGAACTGTT
AGTTGTTGGCGCCGTTCTGA

Product: aspartate alpha-decarboxylase

Products: NA

Alternate protein names: Aspartate alpha-decarboxylase

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MLKILRAKLHGIRVTECVLDYHGSITLDPEICGLAGIMPLEFVYIWNKHSGQRISTYVIYGEAGSRCCILNGAAARTCQK
GDEVIISAFEYVAGPGDISQRSPVVLTFDAHNRVQERLRYIVEQKDGGMSFNIADDPLPEA

Sequences:

>Translated_141_residues
MLKILRAKLHGIRVTECVLDYHGSITLDPEICGLAGIMPLEFVYIWNKHSGQRISTYVIYGEAGSRCCILNGAAARTCQK
GDEVIISAFEYVAGPGDISQRSPVVLTFDAHNRVQERLRYIVEQKDGGMSFNIADDPLPEA
>Mature_141_residues
MLKILRAKLHGIRVTECVLDYHGSITLDPEICGLAGIMPLEFVYIWNKHSGQRISTYVIYGEAGSRCCILNGAAARTCQK
GDEVIISAFEYVAGPGDISQRSPVVLTFDAHNRVQERLRYIVEQKDGGMSFNIADDPLPEA

Specific function: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine

COG id: COG0853

COG function: function code H; Aspartate 1-decarboxylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the panD family

Homologues:

Organism=Escherichia coli, GI1786323, Length=119, Percent_Identity=38.655462184874, Blast_Score=78, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAND_DESDA (B8IZG2)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002479567.1
- GeneID:   7284662
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_0982
- HOGENOM:   HBG302821
- ProtClustDB:   PRK05449
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00446
- InterPro:   IPR009010
- InterPro:   IPR003190
- Gene3D:   G3DSA:2.40.40.20
- PANTHER:   PTHR21012
- PIRSF:   PIRSF006246
- ProDom:   PD009294

Pfam domain/function: PF02261 Asp_decarbox; SSF50692 Asp_decarb_fold

EC number: =4.1.1.11

Molecular weight: Translated: 15585; Mature: 15585

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: ACT_SITE 24-24 ACT_SITE 57-57 BINDING 56-56

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKILRAKLHGIRVTECVLDYHGSITLDPEICGLAGIMPLEFVYIWNKHSGQRISTYVIY
CCEEEEHHHCCEEEEEEEECCCCCEEECHHHHCCCCCCEEEEEEEEECCCCCEEEEEEEE
GEAGSRCCILNGAAARTCQKGDEVIISAFEYVAGPGDISQRSPVVLTFDAHNRVQERLRY
CCCCCEEEEEECCHHHHHCCCCHHEEEHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHH
IVEQKDGGMSFNIADDPLPEA
HHHCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MLKILRAKLHGIRVTECVLDYHGSITLDPEICGLAGIMPLEFVYIWNKHSGQRISTYVIY
CCEEEEHHHCCEEEEEEEECCCCCEEECHHHHCCCCCCEEEEEEEEECCCCCEEEEEEEE
GEAGSRCCILNGAAARTCQKGDEVIISAFEYVAGPGDISQRSPVVLTFDAHNRVQERLRY
CCCCCEEEEEECCHHHHHCCCCHHEEEHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHH
IVEQKDGGMSFNIADDPLPEA
HHHCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA