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The map label for this gene is surA [H]

Identifier: 220904185

GI number: 220904185

Start: 1062389

End: 1063324

Strand: Direct

Name: surA [H]

Synonym: Ddes_0912

Alternate gene names: 220904185

Gene position: 1062389-1063324 (Clockwise)

Preceding gene: 220904184

Following gene: 220904186

Centisome position: 36.97

GC content: 55.88

Gene sequence:

>936_bases
GTGAGGAAGACACTTGTTTTGCTGCTGGCGGTCATACTTGTGGCTGCATGCGGCGTGCAGGCCGCCCAGCTCAATAAAGT
GGCCGCCGTGGTCAATGGGCAGGTCATTACCATGTTTGATCTGCAAAAAAATGCCCTGCCCGATATGGCGCGCGCCAGGC
TTAATCCGGATAATCCCGCTGACGCCAAACAGGTGGATGCTATTTTCCGCAAGGTTCTGGACATGATGATCATGGATATC
CTCATTGCCCAGGAAGCCAGAAGGCTGAAGGTCAGCGTGTCGCCTGCAGACATTGACAATGAGATTGCCAAGCTCATGCA
GGGTCGCAACATGACCAAGCAGCAATTTGAGGAACAGCTTGCCAGACAGAAAAGCAGCGTTGCAGAACTGCGTGGCAATA
TTGAGAAAAGCCTGTTAAGACAGAAGATCATGAGCATGGAGGTTGGCCGCAAGGTGGTGGTCACCCCCGAGGAAATCCGC
GCATACTATGAGGCCCACAAGGACACCATGTATGACCGCAACGGCCTGCACATGGGGGTTATGGTTTATTCTCCCAAGGT
GAACGCCGCCTCCATCGCTGCCCAGATCCGTTCCGGTGCGCTGACGTTTGAAGAAGCCGCGCGCAAGTACTCCATCGCGC
CCAACAAGGAAAAGGGCGGCGATATGGGGCCGGTGGAATGGGACCGCCTGAATCCCGAGTGGGAGGGCCGCCTCACCAAG
ATGAAGCCGGGCGACGTGACGGAGCTTTTTGACTTGCAGGGGCATAAGGCCCAGGTGCATCTCTTCCGCCCCGGAGGGGG
AGGAGTGAAAATGCTCAGCCTTGAAGAGGCCAAGCCGCAGATTGACGCCATATTGCGGCAGCCCAAGGCTATGGAACGTT
TTGACGATTATACTGGCCAGTTGCGCAGCAAGGCCGTGATAGATATTCGCTTGTAG

Upstream 100 bases:

>100_bases
CGGGGACACCTCTGCCGGGCAGACATTGCATGTCGCGTTGTTTTGGGCTAAAAATCTGAGGATAAACAGGCGCACTGCGT
CTTACATGAGGGAGAAACCC

Downstream 100 bases:

>100_bases
CGCGTCTGACCGGGCGCAGCGTGGCCGTGTTTGCCCTGGCCCGCAGCGCCGTTCCGGTTGCGGCCGGGCCTGAAACGGCC
CGCGCCGTGCCGCCGGCAAC

Product: SurA domain-containing protein

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MRKTLVLLLAVILVAACGVQAAQLNKVAAVVNGQVITMFDLQKNALPDMARARLNPDNPADAKQVDAIFRKVLDMMIMDI
LIAQEARRLKVSVSPADIDNEIAKLMQGRNMTKQQFEEQLARQKSSVAELRGNIEKSLLRQKIMSMEVGRKVVVTPEEIR
AYYEAHKDTMYDRNGLHMGVMVYSPKVNAASIAAQIRSGALTFEEAARKYSIAPNKEKGGDMGPVEWDRLNPEWEGRLTK
MKPGDVTELFDLQGHKAQVHLFRPGGGGVKMLSLEEAKPQIDAILRQPKAMERFDDYTGQLRSKAVIDIRL

Sequences:

>Translated_311_residues
MRKTLVLLLAVILVAACGVQAAQLNKVAAVVNGQVITMFDLQKNALPDMARARLNPDNPADAKQVDAIFRKVLDMMIMDI
LIAQEARRLKVSVSPADIDNEIAKLMQGRNMTKQQFEEQLARQKSSVAELRGNIEKSLLRQKIMSMEVGRKVVVTPEEIR
AYYEAHKDTMYDRNGLHMGVMVYSPKVNAASIAAQIRSGALTFEEAARKYSIAPNKEKGGDMGPVEWDRLNPEWEGRLTK
MKPGDVTELFDLQGHKAQVHLFRPGGGGVKMLSLEEAKPQIDAILRQPKAMERFDDYTGQLRSKAVIDIRL
>Mature_311_residues
MRKTLVLLLAVILVAACGVQAAQLNKVAAVVNGQVITMFDLQKNALPDMARARLNPDNPADAKQVDAIFRKVLDMMIMDI
LIAQEARRLKVSVSPADIDNEIAKLMQGRNMTKQQFEEQLARQKSSVAELRGNIEKSLLRQKIMSMEVGRKVVVTPEEIR
AYYEAHKDTMYDRNGLHMGVMVYSPKVNAASIAAQIRSGALTFEEAARKYSIAPNKEKGGDMGPVEWDRLNPEWEGRLTK
MKPGDVTELFDLQGHKAQVHLFRPGGGGVKMLSLEEAKPQIDAILRQPKAMERFDDYTGQLRSKAVIDIRL

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

None

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 34754; Mature: 34754

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKTLVLLLAVILVAACGVQAAQLNKVAAVVNGQVITMFDLQKNALPDMARARLNPDNPA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCHHCCCHHHHHCCCCCCCC
DAKQVDAIFRKVLDMMIMDILIAQEARRLKVSVSPADIDNEIAKLMQGRNMTKQQFEEQL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHH
ARQKSSVAELRGNIEKSLLRQKIMSMEVGRKVVVTPEEIRAYYEAHKDTMYDRNGLHMGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHCCCCCCCEEEE
MVYSPKVNAASIAAQIRSGALTFEEAARKYSIAPNKEKGGDMGPVEWDRLNPEWEGRLTK
EEECCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
MKPGDVTELFDLQGHKAQVHLFRPGGGGVKMLSLEEAKPQIDAILRQPKAMERFDDYTGQ
CCCCCHHHHHHCCCCEEEEEEECCCCCCEEEEECHHCCHHHHHHHHCCHHHHHHHHHHHH
LRSKAVIDIRL
HCCCEEEEEEC
>Mature Secondary Structure
MRKTLVLLLAVILVAACGVQAAQLNKVAAVVNGQVITMFDLQKNALPDMARARLNPDNPA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCHHCCCHHHHHCCCCCCCC
DAKQVDAIFRKVLDMMIMDILIAQEARRLKVSVSPADIDNEIAKLMQGRNMTKQQFEEQL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHH
ARQKSSVAELRGNIEKSLLRQKIMSMEVGRKVVVTPEEIRAYYEAHKDTMYDRNGLHMGV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHCCCCCCCEEEE
MVYSPKVNAASIAAQIRSGALTFEEAARKYSIAPNKEKGGDMGPVEWDRLNPEWEGRLTK
EEECCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
MKPGDVTELFDLQGHKAQVHLFRPGGGGVKMLSLEEAKPQIDAILRQPKAMERFDDYTGQ
CCCCCHHHHHHCCCCEEEEEEECCCCCCEEEEECHHCCHHHHHHHHCCHHHHHHHHHHHH
LRSKAVIDIRL
HCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA