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The map label for this gene is pyrR [H]

Identifier: 220904179

GI number: 220904179

Start: 1055789

End: 1056328

Strand: Reverse

Name: pyrR [H]

Synonym: Ddes_0906

Alternate gene names: 220904179

Gene position: 1056328-1055789 (Counterclockwise)

Preceding gene: 220904192

Following gene: 220904178

Centisome position: 36.76

GC content: 63.89

Gene sequence:

>540_bases
ATGGCTACAACCCTGCTGCTTGAAGAACATGAAATGACCCGCATGCTGGAGCGCCTGGCGTCCCAGATTATGGAACGCCA
CGCAGACTGCGGGCATGTCATGCTTGTAGGCATCGAGCGGCGCGGCGCGGACCTTGCCCACCGCTTGGCAGGCCTGCTGC
AGGAGCGCCTCGGTCACCCGGTGCTGCTGGGTACGCTGGATATCAATCTTTACCGTGACGACTGGACAAGCCTTGAGGCC
CAGCCGCATATCGGCCAGTCGCGCATACCCGCAAGCGTGGACGGGCGCGTGATCGTTCTTGTGGATGACGTGCTCTATAC
GGGCCGAACCATCCGCGCCGCCCTTGAGGCCCTGCTGGACTATGGCCGCCCCAGGGCTGTGGAACTGCTGGCCCTTATAG
ACCGGGGTCATCGCGAACTGCCCATACATGCCGACTATGTGGGCCGCACGGTCAACACCAGCCGCCAGGAGCGCGTGGAC
GTGCTGCTCACCGAAAGGGACGGGCAGGACGCGGTTCACCTTACAGCCAGCCCCGCCTGA

Upstream 100 bases:

>100_bases
GTAACTAAGGCCATGCACCGGGCTTGTCAATTACCGGGGGACTTTTCTTCAGCCACAAAAAGCGTTAACCTGCTTTCAGC
GAGACGTTACGGGAGGAAAG

Downstream 100 bases:

>100_bases
TTTCAGGGGCAACCTGCCGGGACCGGATTTGCCTGAAGCATCTCCCGGCTGTAACCCTGCCGGGCGGCCACGCCGCCCCT
GCCCACGGCCCAGGGCCGTG

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MATTLLLEEHEMTRMLERLASQIMERHADCGHVMLVGIERRGADLAHRLAGLLQERLGHPVLLGTLDINLYRDDWTSLEA
QPHIGQSRIPASVDGRVIVLVDDVLYTGRTIRAALEALLDYGRPRAVELLALIDRGHRELPIHADYVGRTVNTSRQERVD
VLLTERDGQDAVHLTASPA

Sequences:

>Translated_179_residues
MATTLLLEEHEMTRMLERLASQIMERHADCGHVMLVGIERRGADLAHRLAGLLQERLGHPVLLGTLDINLYRDDWTSLEA
QPHIGQSRIPASVDGRVIVLVDDVLYTGRTIRAALEALLDYGRPRAVELLALIDRGHRELPIHADYVGRTVNTSRQERVD
VLLTERDGQDAVHLTASPA
>Mature_178_residues
ATTLLLEEHEMTRMLERLASQIMERHADCGHVMLVGIERRGADLAHRLAGLLQERLGHPVLLGTLDINLYRDDWTSLEAQ
PHIGQSRIPASVDGRVIVLVDDVLYTGRTIRAALEALLDYGRPRAVELLALIDRGHRELPIHADYVGRTVNTSRQERVDV
LLTERDGQDAVHLTASPA

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 20003; Mature: 19872

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTLLLEEHEMTRMLERLASQIMERHADCGHVMLVGIERRGADLAHRLAGLLQERLGHP
CCCEEEECHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCC
VLLGTLDINLYRDDWTSLEAQPHIGQSRIPASVDGRVIVLVDDVLYTGRTIRAALEALLD
EEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHCCHHHHHHHHHHHH
YGRPRAVELLALIDRGHRELPIHADYVGRTVNTSRQERVDVLLTERDGQDAVHLTASPA
CCCCHHHHHHHHHHCCCCCCCEEHHHHCCCCCCCCHHHEEEEEECCCCCCEEEEEECCC
>Mature Secondary Structure 
ATTLLLEEHEMTRMLERLASQIMERHADCGHVMLVGIERRGADLAHRLAGLLQERLGHP
CCEEEECHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCC
VLLGTLDINLYRDDWTSLEAQPHIGQSRIPASVDGRVIVLVDDVLYTGRTIRAALEALLD
EEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHCCHHHHHHHHHHHH
YGRPRAVELLALIDRGHRELPIHADYVGRTVNTSRQERVDVLLTERDGQDAVHLTASPA
CCCCHHHHHHHHHHCCCCCCCEEHHHHCCCCCCCCHHHEEEEEECCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA