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The map label for this gene is mltB [C]

Identifier: 220904142

GI number: 220904142

Start: 1018661

End: 1019911

Strand: Direct

Name: mltB [C]

Synonym: Ddes_0869

Alternate gene names: 220904142

Gene position: 1018661-1019911 (Clockwise)

Preceding gene: 220904141

Following gene: 220904144

Centisome position: 35.45

GC content: 61.63

Gene sequence:

>1251_bases
ATGACCATAACGCTGGCCGGAAAAGCTTCTTTAGCCACGTTCAGAACGGTCAGCCTGATATGCTGTCTGGTCTGCGGCAT
GCTCGTGGCCGCCTGCGGCGGCGCGCATACCCAGCCGGTTTCAGAACCTGAAAGCGCCGGTCCGGCCCATGGGGTCGTTC
CGGGCAAGGTTGCCGGCCACGATTTGCCCGCAACGGGCGAAGCGGTAACTGGCCGGAGCGGCGGGGGAGACCTCTCCCCC
GTTCGTCCCGGCCTCCAGGCGCAGCCGGAACTACCCGGTAACGAAAATGTCTCGGAGGCGGGTACGTCTGCCATGGCCCC
GGTCTGGCTGCCGCTGGCCATGCGGCTTGCCGCCGATGGGCTTTCCGGACCGCGGGTAGATGCCCTGCTGGGTACGCTGG
CCTCTACGCCCAGTCAGTCACCTATGGGCCGCAAAATGCTTGAGCTTTACAAAAGCCGTTTCATGCCCCGGCCTCCTTCC
GCCAAGCCCACGTCCACAACCTACTACAAAGGGGTCGTAACGGAACAGAATGCCCGCTTGTGCCGCGCGTTCATTGCCGA
GCATAAACAGGCGTTCAGTCAGGCCCAGGCCCGCTACGGAGTCCCTTCGTCCGTGGCAGTGTCTCTGCTTTTTGTGGAAA
CGCGCCTTGGCAAGGTGCTGGCTGATGTGCCGGAAAACGCCCTTTACACCCTGGCTAGTATGGCCGTGAGCCGTGATCCT
TCGCAAATCGATCAATGGCTGCCGCGTATGCCGGGCTATGAAGAACACATGGACTGGCTGCAGGAAACCATGCCGAAACG
TGCCGACTGGGCCTATAAAGAAGTACGGGCTCTTGTGCGCCATATCCTGCAGGATGATCTTGATCCCCAGTACCTGCCCA
GCTCCATTTATGGGGCGGTCGGCCTGTGTCAGTTCATGCCCTCCAATATCGCGGCGTATGGAGCGGACGGTGACGATGAC
GGCAAGGTTGACCTGTTTCATGTGCCGGATGCTGTGGCAAGCCTGTCCAACTATCTGGTACGGCATGGCTGGAAGCCCGG
CATAAGCCGCGCGCAGCAGCACAAGGTGCTCATGACCTATAACCGGTCCACGGTCTATGCCAATACCATTCTTGCCCTGG
CCGATCTCGTGCAAAAGTCCGAAGCTGCGGCAGGCAAGGCCGCTGCACGGGGGCGGCCGGAAAAAAGCGCTGCTTCCGGC
AAAGGCGGCAAGGCCCGCCCTTCCGGTGTGAACGCCGGGCAGGGGTCTTGA

Upstream 100 bases:

>100_bases
GTTCTGATTCTGCGAACTTCCCCGAAACAACACTCACACCCGACCTGCTGACCAGACGTTTGCTGGGCCGGGTGGTGTGG
GTATTTCAGGACTTATAAAC

Downstream 100 bases:

>100_bases
AGCGGCCGGTACTACACGAAGCCATCAGCCTTGCTGTCACGACAGGGGATGACGCGAATATACCCATGCCGTTTGCCTGA
TGTTCCGTTTACGGAATATT

Product: Membrane-bound lytic murein transglycosylase B-like protein

Products: Muramic Acid Residue [C]

Alternate protein names: Membrane-Bound Lytic Murein Transglycosylase B-Like; Membrane-Bound Lytic Murein Transglycosylase B; Transglycosylase Domain Protein; Transglycosylase Domain-Containing Protein; Murein Hydrolase B

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MTITLAGKASLATFRTVSLICCLVCGMLVAACGGAHTQPVSEPESAGPAHGVVPGKVAGHDLPATGEAVTGRSGGGDLSP
VRPGLQAQPELPGNENVSEAGTSAMAPVWLPLAMRLAADGLSGPRVDALLGTLASTPSQSPMGRKMLELYKSRFMPRPPS
AKPTSTTYYKGVVTEQNARLCRAFIAEHKQAFSQAQARYGVPSSVAVSLLFVETRLGKVLADVPENALYTLASMAVSRDP
SQIDQWLPRMPGYEEHMDWLQETMPKRADWAYKEVRALVRHILQDDLDPQYLPSSIYGAVGLCQFMPSNIAAYGADGDDD
GKVDLFHVPDAVASLSNYLVRHGWKPGISRAQQHKVLMTYNRSTVYANTILALADLVQKSEAAAGKAAARGRPEKSAASG
KGGKARPSGVNAGQGS

Sequences:

>Translated_416_residues
MTITLAGKASLATFRTVSLICCLVCGMLVAACGGAHTQPVSEPESAGPAHGVVPGKVAGHDLPATGEAVTGRSGGGDLSP
VRPGLQAQPELPGNENVSEAGTSAMAPVWLPLAMRLAADGLSGPRVDALLGTLASTPSQSPMGRKMLELYKSRFMPRPPS
AKPTSTTYYKGVVTEQNARLCRAFIAEHKQAFSQAQARYGVPSSVAVSLLFVETRLGKVLADVPENALYTLASMAVSRDP
SQIDQWLPRMPGYEEHMDWLQETMPKRADWAYKEVRALVRHILQDDLDPQYLPSSIYGAVGLCQFMPSNIAAYGADGDDD
GKVDLFHVPDAVASLSNYLVRHGWKPGISRAQQHKVLMTYNRSTVYANTILALADLVQKSEAAAGKAAARGRPEKSAASG
KGGKARPSGVNAGQGS
>Mature_415_residues
TITLAGKASLATFRTVSLICCLVCGMLVAACGGAHTQPVSEPESAGPAHGVVPGKVAGHDLPATGEAVTGRSGGGDLSPV
RPGLQAQPELPGNENVSEAGTSAMAPVWLPLAMRLAADGLSGPRVDALLGTLASTPSQSPMGRKMLELYKSRFMPRPPSA
KPTSTTYYKGVVTEQNARLCRAFIAEHKQAFSQAQARYGVPSSVAVSLLFVETRLGKVLADVPENALYTLASMAVSRDPS
QIDQWLPRMPGYEEHMDWLQETMPKRADWAYKEVRALVRHILQDDLDPQYLPSSIYGAVGLCQFMPSNIAAYGADGDDDG
KVDLFHVPDAVASLSNYLVRHGWKPGISRAQQHKVLMTYNRSTVYANTILALADLVQKSEAAAGKAAARGRPEKSAASGK
GGKARPSGVNAGQGS

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG2951

COG function: function code M; Membrane-bound lytic murein transglycosylase B

Gene ontology:

Cell location: Attached To The Outer Membrane By A Lipid Anchor And Exposed To The Periplasmic Protein Side [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 44006; Mature: 43874

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITLAGKASLATFRTVSLICCLVCGMLVAACGGAHTQPVSEPESAGPAHGVVPGKVAGH
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DLPATGEAVTGRSGGGDLSPVRPGLQAQPELPGNENVSEAGTSAMAPVWLPLAMRLAADG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHCCHHHHHHHHHHHHCC
LSGPRVDALLGTLASTPSQSPMGRKMLELYKSRFMPRPPSAKPTSTTYYKGVVTEQNARL
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECEEECCHHHH
CRAFIAEHKQAFSQAQARYGVPSSVAVSLLFVETRLGKVLADVPENALYTLASMAVSRDP
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCH
SQIDQWLPRMPGYEEHMDWLQETMPKRADWAYKEVRALVRHILQDDLDPQYLPSSIYGAV
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHH
GLCQFMPSNIAAYGADGDDDGKVDLFHVPDAVASLSNYLVRHGWKPGISRAQQHKVLMTY
HHHHHCCCCCEEECCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEE
NRSTVYANTILALADLVQKSEAAAGKAAARGRPEKSAASGKGGKARPSGVNAGQGS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TITLAGKASLATFRTVSLICCLVCGMLVAACGGAHTQPVSEPESAGPAHGVVPGKVAGH
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DLPATGEAVTGRSGGGDLSPVRPGLQAQPELPGNENVSEAGTSAMAPVWLPLAMRLAADG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHCCHHHHHHHHHHHHCC
LSGPRVDALLGTLASTPSQSPMGRKMLELYKSRFMPRPPSAKPTSTTYYKGVVTEQNARL
CCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECEEECCHHHH
CRAFIAEHKQAFSQAQARYGVPSSVAVSLLFVETRLGKVLADVPENALYTLASMAVSRDP
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCH
SQIDQWLPRMPGYEEHMDWLQETMPKRADWAYKEVRALVRHILQDDLDPQYLPSSIYGAV
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHH
GLCQFMPSNIAAYGADGDDDGKVDLFHVPDAVASLSNYLVRHGWKPGISRAQQHKVLMTY
HHHHHCCCCCEEECCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHCCEEEEE
NRSTVYANTILALADLVQKSEAAAGKAAARGRPEKSAASGKGGKARPSGVNAGQGS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA