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The map label for this gene is hycD [H]

Identifier: 220904051

GI number: 220904051

Start: 910029

End: 910970

Strand: Reverse

Name: hycD [H]

Synonym: Ddes_0777

Alternate gene names: 220904051

Gene position: 910970-910029 (Counterclockwise)

Preceding gene: 220904052

Following gene: 220904050

Centisome position: 31.7

GC content: 61.78

Gene sequence:

>942_bases
ATGAGACAAGACATAGCCGTCTATTTCGTGCAGTTTGCGCTGGCCCTTGTTCTGGCTCCGCTGCTGCCCGGCATTATCAA
CAGGGTCAAGGCCAAGTTTGCAGGCAGGCATGGCAAACCCCTCCTGCAAACCTATTATGACCTCGCGCGGCTCATGCGCA
AGGGCGAGGTCATCAGCCGCACAACCACCTGGGTTTTTGCCTGCGGTCCGGCGGTAGCGCTGGCCACAGCCCTTTGCGCC
ATTGCCCTGCTGCCGCTAGGCGGAGCGGCCTCGCCCCTGGCTTTCGGCGGCGATTTTATTCTGGCAGCCTATCTGCTCGG
CATGGGCCGCTTTGCCATCATGCTTTCGGCCCTTGATACCGGCTCGGCCTTCGAGGGCATGGGCGCAAGCCGTGAGGCCA
CCTTTGCGGCACTGGCGGAACCGCTCTTTTTTCTGGCGTTGCTGGTGCTTACCAGCGTCACCCTGGATATGGGACGCGGC
CCGCACGCGGCCTTTTCGCTTTCATCCATGTTTGGGGGGCAGATTGCCGGAGCCTGGGCCATGGGCCGGGGCGAACTTCT
GCTTTTGCCGTGCATTTTCTTTATTCTGCTGCTGGTGGAAAACTGCCGCATTCCTGTGGATGATCCCAACACCCACCTGG
AACTGACGATGATCCACGAGGTTATGGTGCTGGACCATTCCGGTCCCAACCTGGCCATGATCGTCTACGGTGCAGCGCTC
AAACTGTGGTTTTTCGCGGCGCTTATCGCCGGACTGGTTACCCCCGCCCTGCCCCTGTGGCAGCAGGCTGGGCTGCGCGT
ACTCATCGTGCTGCTGCTGGCCGTGGTGGTGGGCATTGTGGAATCTGTCATGGCGCGTCTGCGCATGGACCGTGTGCCTT
ACCTGCTCGGCGGCGCATCGGCCATGGCTGCGCTGGCGCTCATCCTGACCCAGGCGAGGTAG

Upstream 100 bases:

>100_bases
TGTGCAATGCCTGCAAGATCATGCAACACGGCAAAATACATCTTTATATTCTTTACATTCTGGCCACAGTTGTGGGTCTG
CTTGTATGGGGGCTGAGCGC

Downstream 100 bases:

>100_bases
AAGCATGGAATCCCTTTTGCAATCCTGCCTGTTCCTGCTCATGCTGAACAACCTGCTCATGCTGGGCACAACACGGCTTA
TGTGGCTCATACGTCTTACC

Product: respiratory-chain NADH dehydrogenase, subunit 1

Products: NA

Alternate protein names: FHL subunit 4; Hydrogenase 3 component D [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MRQDIAVYFVQFALALVLAPLLPGIINRVKAKFAGRHGKPLLQTYYDLARLMRKGEVISRTTTWVFACGPAVALATALCA
IALLPLGGAASPLAFGGDFILAAYLLGMGRFAIMLSALDTGSAFEGMGASREATFAALAEPLFFLALLVLTSVTLDMGRG
PHAAFSLSSMFGGQIAGAWAMGRGELLLLPCIFFILLLVENCRIPVDDPNTHLELTMIHEVMVLDHSGPNLAMIVYGAAL
KLWFFAALIAGLVTPALPLWQQAGLRVLIVLLLAVVVGIVESVMARLRMDRVPYLLGGASAMAALALILTQAR

Sequences:

>Translated_313_residues
MRQDIAVYFVQFALALVLAPLLPGIINRVKAKFAGRHGKPLLQTYYDLARLMRKGEVISRTTTWVFACGPAVALATALCA
IALLPLGGAASPLAFGGDFILAAYLLGMGRFAIMLSALDTGSAFEGMGASREATFAALAEPLFFLALLVLTSVTLDMGRG
PHAAFSLSSMFGGQIAGAWAMGRGELLLLPCIFFILLLVENCRIPVDDPNTHLELTMIHEVMVLDHSGPNLAMIVYGAAL
KLWFFAALIAGLVTPALPLWQQAGLRVLIVLLLAVVVGIVESVMARLRMDRVPYLLGGASAMAALALILTQAR
>Mature_313_residues
MRQDIAVYFVQFALALVLAPLLPGIINRVKAKFAGRHGKPLLQTYYDLARLMRKGEVISRTTTWVFACGPAVALATALCA
IALLPLGGAASPLAFGGDFILAAYLLGMGRFAIMLSALDTGSAFEGMGASREATFAALAEPLFFLALLVLTSVTLDMGRG
PHAAFSLSSMFGGQIAGAWAMGRGELLLLPCIFFILLLVENCRIPVDDPNTHLELTMIHEVMVLDHSGPNLAMIVYGAAL
KLWFFAALIAGLVTPALPLWQQAGLRVLIVLLLAVVVGIVESVMARLRMDRVPYLLGGASAMAALALILTQAR

Specific function: Hydrogen metabolism; FHL pathway. [C]

COG id: COG0650

COG function: function code C; Formate hydrogenlyase subunit 4

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI1789077, Length=312, Percent_Identity=29.4871794871795, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082115, Length=270, Percent_Identity=35.1851851851852, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: NA

Molecular weight: Translated: 33308; Mature: 33308

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQDIAVYFVQFALALVLAPLLPGIINRVKAKFAGRHGKPLLQTYYDLARLMRKGEVISR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHH
TTTWVFACGPAVALATALCAIALLPLGGAASPLAFGGDFILAAYLLGMGRFAIMLSALDT
HHHEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
GSAFEGMGASREATFAALAEPLFFLALLVLTSVTLDMGRGPHAAFSLSSMFGGQIAGAWA
CCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHC
MGRGELLLLPCIFFILLLVENCRIPVDDPNTHLELTMIHEVMVLDHSGPNLAMIVYGAAL
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHEEECCCCCEEEHHHHHHH
KLWFFAALIAGLVTPALPLWQQAGLRVLIVLLLAVVVGIVESVMARLRMDRVPYLLGGAS
HHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHH
AMAALALILTQAR
HHHHHHHHHHCCC
>Mature Secondary Structure
MRQDIAVYFVQFALALVLAPLLPGIINRVKAKFAGRHGKPLLQTYYDLARLMRKGEVISR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHH
TTTWVFACGPAVALATALCAIALLPLGGAASPLAFGGDFILAAYLLGMGRFAIMLSALDT
HHHEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
GSAFEGMGASREATFAALAEPLFFLALLVLTSVTLDMGRGPHAAFSLSSMFGGQIAGAWA
CCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHC
MGRGELLLLPCIFFILLLVENCRIPVDDPNTHLELTMIHEVMVLDHSGPNLAMIVYGAAL
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHEEECCCCCEEEHHHHHHH
KLWFFAALIAGLVTPALPLWQQAGLRVLIVLLLAVVVGIVESVMARLRMDRVPYLLGGAS
HHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHH
AMAALALILTQAR
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2187144; 9278503 [H]