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The map label for this gene is clpX [H]

Identifier: 220903966

GI number: 220903966

Start: 821384

End: 822676

Strand: Direct

Name: clpX [H]

Synonym: Ddes_0692

Alternate gene names: 220903966

Gene position: 821384-822676 (Clockwise)

Preceding gene: 220903965

Following gene: 220903967

Centisome position: 28.59

GC content: 57.77

Gene sequence:

>1293_bases
ATGGCCAAGAACGATAAGAACAAGGTCAGCGAACCTTTGAGCTGCTCCTTCTGCGGGCGCAGCGAACTGGAGGTGCGCAA
CCTCATCGTGCAGGACGGCGCGAGCATTTGCGACAAATGCGTCAAGGCCTGCAACGACATCATTGTGCGCGACCAGATGG
AAGTTACCGAGGACGACGGGCCGCTGCTCTCGCCTCAGGAAATCAAGGACAGGCTCGACCAGTACGTCATAGGGCAGCAC
GAAGCCAAGAAAATTCTTTCCGTGGCCGTGCACAATCACTATAAACGCGTGTTCTATGCCGACGCCCTGGGCGACGACGT
GGAACTGGAAAAAAGCAATATCCTGCTGGTGGGGCCTTCGGGCAGCGGCAAAACGCTGCTGGCAAAAACTCTGGCCCGTG
TGCTGCGCGTACCCTTTGCCATAGCCGACGCCACCACCCTTACAGAGGCGGGTTATGTGGGCGAGGATGTGGAAAACATT
CTGGTCCAGCTGCTGCAGAATGCCGACTATGACCTTGAAGCCGCCAGCAAGGGTATCATCTACGTGGACGAAATCGACAA
GATTTCCCGCAAGGGCGACGGCCCCTCCATTACGCGCGACGTGTCGGGCGAAGGCGTGCAGCAGGCCCTGCTGAAAATCA
TTGAAGGCACCGAGGCCAACATTCCTCCCAAGGGCGGGCGCAAGCACCCGCAGCAGGAATTTATCCGCATGGATACGCGG
AATATCCTGTTTATCGTAGGCGGAGCCTTTGTGGGCCTGGACAAGATTGTGGAATCGCGCATGAGCGGCGGGGCTATGGG
CTTCGGGGCCAAAGTCCGCTCCAGCAAGGAACTGCCCCTGGGCGAACTGCTGGACAGGATACATCCTCAGGACCTGGTCA
AATTCGGCCTGATTCCCGAATTTGTGGGGCGTATTCCCATCATCACCCACGTGGATGAGCTGGACGAAGCGGACCTGGTG
CGCATCCTTACCGAGCCGAAAAATGCCCTGGTGCGTCAGTACCAGAAGCTGTTCGGCCTTGAAAATGTGACCCTGCGTTT
CACGCCCAATGCCCTCAAATCCATTGCTTCCAAGGCCATTGAGCGCAAAACCGGCGCGCGCGGCCTGCGCAACGTGATGG
AGCGCATTATGCTTGATATCATGTTCAGGCTGCCCTCCATGCCCAATGTGCGTGAATGCCTCATCAACCGCGCCGTGATC
GAAAAGGGCAAGGAACCTGTGCTCCTGTTCGGTGAGGCGGACGAAAACCTTGTGCAGGAAAAAAAGCAGGCAGGTGGCGA
CCGGGCATCCTAG

Upstream 100 bases:

>100_bases
GCGATAACTTTTTGACTCCTGAAGAAGCCAAAGACCTGGGCATTATCGACCGCGTACTGGTTTCGCGCCAGGACATGGCT
CAGGAAAAGAGCGAATAATC

Downstream 100 bases:

>100_bases
GGCATTTTTATTGTAAAATGCTTGGATGGCGGTGTGACATGGTTCCTGCTTCTGGCTGCCTGTCTTTGCCGCAACGGTTG
AAGACGGTTTTGGGCGGGCA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MAKNDKNKVSEPLSCSFCGRSELEVRNLIVQDGASICDKCVKACNDIIVRDQMEVTEDDGPLLSPQEIKDRLDQYVIGQH
EAKKILSVAVHNHYKRVFYADALGDDVELEKSNILLVGPSGSGKTLLAKTLARVLRVPFAIADATTLTEAGYVGEDVENI
LVQLLQNADYDLEAASKGIIYVDEIDKISRKGDGPSITRDVSGEGVQQALLKIIEGTEANIPPKGGRKHPQQEFIRMDTR
NILFIVGGAFVGLDKIVESRMSGGAMGFGAKVRSSKELPLGELLDRIHPQDLVKFGLIPEFVGRIPIITHVDELDEADLV
RILTEPKNALVRQYQKLFGLENVTLRFTPNALKSIASKAIERKTGARGLRNVMERIMLDIMFRLPSMPNVRECLINRAVI
EKGKEPVLLFGEADENLVQEKKQAGGDRAS

Sequences:

>Translated_430_residues
MAKNDKNKVSEPLSCSFCGRSELEVRNLIVQDGASICDKCVKACNDIIVRDQMEVTEDDGPLLSPQEIKDRLDQYVIGQH
EAKKILSVAVHNHYKRVFYADALGDDVELEKSNILLVGPSGSGKTLLAKTLARVLRVPFAIADATTLTEAGYVGEDVENI
LVQLLQNADYDLEAASKGIIYVDEIDKISRKGDGPSITRDVSGEGVQQALLKIIEGTEANIPPKGGRKHPQQEFIRMDTR
NILFIVGGAFVGLDKIVESRMSGGAMGFGAKVRSSKELPLGELLDRIHPQDLVKFGLIPEFVGRIPIITHVDELDEADLV
RILTEPKNALVRQYQKLFGLENVTLRFTPNALKSIASKAIERKTGARGLRNVMERIMLDIMFRLPSMPNVRECLINRAVI
EKGKEPVLLFGEADENLVQEKKQAGGDRAS
>Mature_429_residues
AKNDKNKVSEPLSCSFCGRSELEVRNLIVQDGASICDKCVKACNDIIVRDQMEVTEDDGPLLSPQEIKDRLDQYVIGQHE
AKKILSVAVHNHYKRVFYADALGDDVELEKSNILLVGPSGSGKTLLAKTLARVLRVPFAIADATTLTEAGYVGEDVENIL
VQLLQNADYDLEAASKGIIYVDEIDKISRKGDGPSITRDVSGEGVQQALLKIIEGTEANIPPKGGRKHPQQEFIRMDTRN
ILFIVGGAFVGLDKIVESRMSGGAMGFGAKVRSSKELPLGELLDRIHPQDLVKFGLIPEFVGRIPIITHVDELDEADLVR
ILTEPKNALVRQYQKLFGLENVTLRFTPNALKSIASKAIERKTGARGLRNVMERIMLDIMFRLPSMPNVRECLINRAVIE
KGKEPVLLFGEADENLVQEKKQAGGDRAS

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=331, Percent_Identity=49.2447129909366, Blast_Score=303, Evalue=2e-82,
Organism=Escherichia coli, GI1786642, Length=431, Percent_Identity=57.3085846867749, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1790366, Length=212, Percent_Identity=33.4905660377358, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71982908, Length=312, Percent_Identity=46.7948717948718, Blast_Score=265, Evalue=4e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=292, Percent_Identity=48.6301369863014, Blast_Score=264, Evalue=6e-71,
Organism=Caenorhabditis elegans, GI71988663, Length=393, Percent_Identity=37.6590330788804, Blast_Score=242, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI71988660, Length=251, Percent_Identity=39.0438247011952, Blast_Score=161, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6319704, Length=428, Percent_Identity=41.1214953271028, Blast_Score=272, Evalue=6e-74,
Organism=Drosophila melanogaster, GI24648291, Length=302, Percent_Identity=49.6688741721854, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24648289, Length=302, Percent_Identity=49.6688741721854, Blast_Score=292, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 47408; Mature: 47277

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKNDKNKVSEPLSCSFCGRSELEVRNLIVQDGASICDKCVKACNDIIVRDQMEVTEDDG
CCCCCCHHCCCCCEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
PLLSPQEIKDRLDQYVIGQHEAKKILSVAVHNHYKRVFYADALGDDVELEKSNILLVGPS
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCEECCCCEEEECCC
GSGKTLLAKTLARVLRVPFAIADATTLTEAGYVGEDVENILVQLLQNADYDLEAASKGII
CCCCHHHHHHHHHHHHCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHCCCCCE
YVDEIDKISRKGDGPSITRDVSGEGVQQALLKIIEGTEANIPPKGGRKHPQQEFIRMDTR
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCC
NILFIVGGAFVGLDKIVESRMSGGAMGFGAKVRSSKELPLGELLDRIHPQDLVKFGLIPE
CEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHCCCHH
FVGRIPIITHVDELDEADLVRILTEPKNALVRQYQKLFGLENVTLRFTPNALKSIASKAI
HHCCCCEEECHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHH
ERKTGARGLRNVMERIMLDIMFRLPSMPNVRECLINRAVIEKGKEPVLLFGEADENLVQE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHH
KKQAGGDRAS
HHHCCCCCCC
>Mature Secondary Structure 
AKNDKNKVSEPLSCSFCGRSELEVRNLIVQDGASICDKCVKACNDIIVRDQMEVTEDDG
CCCCCHHCCCCCEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
PLLSPQEIKDRLDQYVIGQHEAKKILSVAVHNHYKRVFYADALGDDVELEKSNILLVGPS
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEECCCCCCCCEECCCCEEEECCC
GSGKTLLAKTLARVLRVPFAIADATTLTEAGYVGEDVENILVQLLQNADYDLEAASKGII
CCCCHHHHHHHHHHHHCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHCCCCCE
YVDEIDKISRKGDGPSITRDVSGEGVQQALLKIIEGTEANIPPKGGRKHPQQEFIRMDTR
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCC
NILFIVGGAFVGLDKIVESRMSGGAMGFGAKVRSSKELPLGELLDRIHPQDLVKFGLIPE
CEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHCCCHH
FVGRIPIITHVDELDEADLVRILTEPKNALVRQYQKLFGLENVTLRFTPNALKSIASKAI
HHCCCCEEECHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHH
ERKTGARGLRNVMERIMLDIMFRLPSMPNVRECLINRAVIEKGKEPVLLFGEADENLVQE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHH
KKQAGGDRAS
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA