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The map label for this gene is gcvR [C]

Identifier: 220903896

GI number: 220903896

Start: 750911

End: 751474

Strand: Direct

Name: gcvR [C]

Synonym: Ddes_0621

Alternate gene names: 220903896

Gene position: 750911-751474 (Clockwise)

Preceding gene: 220903894

Following gene: 220903897

Centisome position: 26.13

GC content: 59.93

Gene sequence:

>564_bases
ATGCACAAGTATACCGCCTCTTTTCTGGGGCGCGACTGCCCCGGAGTGGTGGCCGCAGTCAGCCGCATTCTTGAAGAAAA
CGGCTGCAACATTGAAGAAGTGACCCAGAGCATCCTTTCCGGCGAATTTGCCGCCATTTTTGTGGTGGCCGCCCCCGATG
CCCTGGATGCCCAAAACCTGCACCAGAGGCTGAGCGCCAGCCTGGCCGAGGCCAAAGTGGATCTTTCGGTGCTGGTACGG
CCCGCCATTCAGGGGCAGTGGGGCCAGAGTCTGCACTGCGAACCATTTGTGATCACCGCCGACGGCCCGGACAAGCCCGG
CCTTATCGCGGCCATGAGCCGCGTGTTTGCCCGGCATGATGTGAATATCGAAAGCCTCAAGGCTATTCTGGGCGAAGGCG
GGGCCAATCATGCCCTTTTTGTCTTTGAGGTTATGGTTCCCGATGCCGTTGACCTTGGGCGTCTGCGCCGCGAGCTTTCC
TGCGAGGGCCAGAGCCGCGACCTGAGGGTCAGCGTGCAGCACAGGGATATTTTTGAAGCCGTTCACCGCGTCAGCTCTTT
TTAG

Upstream 100 bases:

>100_bases
GTTTGGCCTTGAAGTTCGCGAGGGTTGCGTATATAGATTTTCTTTCCTGTGACACCTTCCCGTGGCCCTGCCACGGATCA
TTTCCGTAAGGATACGCGTC

Downstream 100 bases:

>100_bases
GGCAGTACAGCTTTTGTATTGCTCTGGCGACCACACGCACGGACCTGCGCGGGCAAACGCCGTAGCGAGTGAGTCTTCAC
CTTGAGAACGCATATCATCA

Product: amino acid-binding ACT domain-containing protein

Products: NA

Alternate protein names: Glycine Cleavage System Transcriptional Repressor; ACT Domain Protein; Glycine Cleavage System Regulatory Protein-Like; Glycine Cleavage System Regulatory Protein

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MHKYTASFLGRDCPGVVAAVSRILEENGCNIEEVTQSILSGEFAAIFVVAAPDALDAQNLHQRLSASLAEAKVDLSVLVR
PAIQGQWGQSLHCEPFVITADGPDKPGLIAAMSRVFARHDVNIESLKAILGEGGANHALFVFEVMVPDAVDLGRLRRELS
CEGQSRDLRVSVQHRDIFEAVHRVSSF

Sequences:

>Translated_187_residues
MHKYTASFLGRDCPGVVAAVSRILEENGCNIEEVTQSILSGEFAAIFVVAAPDALDAQNLHQRLSASLAEAKVDLSVLVR
PAIQGQWGQSLHCEPFVITADGPDKPGLIAAMSRVFARHDVNIESLKAILGEGGANHALFVFEVMVPDAVDLGRLRRELS
CEGQSRDLRVSVQHRDIFEAVHRVSSF
>Mature_187_residues
MHKYTASFLGRDCPGVVAAVSRILEENGCNIEEVTQSILSGEFAAIFVVAAPDALDAQNLHQRLSASLAEAKVDLSVLVR
PAIQGQWGQSLHCEPFVITADGPDKPGLIAAMSRVFARHDVNIESLKAILGEGGANHALFVFEVMVPDAVDLGRLRRELS
CEGQSRDLRVSVQHRDIFEAVHRVSSF

Specific function: Negative Transcriptional Regulator Of The Glycine Cleavage System Operon (Gcv). Does Not Autoregulate Its Own Expression. It Is Not Yet Known How Gcvr Acts As A Repressor. It Does Not Seem To Bind DNA. It Could Interact With Gcva And Suppress Its Activat

COG id: COG3830

COG function: function code T; ACT domain-containing protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 20287; Mature: 20287

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKYTASFLGRDCPGVVAAVSRILEENGCNIEEVTQSILSGEFAAIFVVAAPDALDAQNL
CCCCCHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEEECCCCCCHHHH
HQRLSASLAEAKVDLSVLVRPAIQGQWGQSLHCEPFVITADGPDKPGLIAAMSRVFARHD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCC
VNIESLKAILGEGGANHALFVFEVMVPDAVDLGRLRRELSCEGQSRDLRVSVQHRDIFEA
CCHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHH
VHRVSSF
HHHHHCC
>Mature Secondary Structure
MHKYTASFLGRDCPGVVAAVSRILEENGCNIEEVTQSILSGEFAAIFVVAAPDALDAQNL
CCCCCHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEEECCCCCCHHHH
HQRLSASLAEAKVDLSVLVRPAIQGQWGQSLHCEPFVITADGPDKPGLIAAMSRVFARHD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHCC
VNIESLKAILGEGGANHALFVFEVMVPDAVDLGRLRRELSCEGQSRDLRVSVQHRDIFEA
CCHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHH
VHRVSSF
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA