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The map label for this gene is crp [C]

Identifier: 220903805

GI number: 220903805

Start: 636186

End: 636920

Strand: Reverse

Name: crp [C]

Synonym: Ddes_0528

Alternate gene names: 220903805

Gene position: 636920-636186 (Counterclockwise)

Preceding gene: 220903806

Following gene: 220903804

Centisome position: 22.17

GC content: 60.68

Gene sequence:

>735_bases
ATGACAAACCGACAATATGCCGCCAACACGGATTCTCTTATGAACGAAGAAAGCCTGCAAGCCGCCCCCACCGTGGCCGA
TGCCCTGTGTACCGGCCTGCTGGCGGGCCTGAACCATCACGAAAGGGATGTGCTTGCCCGGCACGCCCGCCTGCAAAGCT
TTGCTCCCGGCGTGGCGCTTTTTCAGGAAGGCGACGAAAGCGCAGACGCCATGCTGCTGCTTTCTGGTCTGGTCAAACTG
TGCCGCCACAGCAGCCAGGGCAAGGAATGTGTACTCCACCTCGTGCATTCCGGCAAATTTATCGACGCGGGCGTACTTTT
TTATGAGGGGGGGCTGCCCATTTCAGCCGTGGCTCTGCAGCACACCACCGTGCTGAGCCTGAACAGGCGCGCGTTTCTGC
ACACCCTTGAAAACAATGCTCCGCTGGCCGTCAGCCTTCTGGGGGCCATGAGCCTGCGCCAGCGCCTGCTTATTACCAAA
ATTGCCGGTTCACAGGGGCGCATATCCGTGGCCGGGCGCGTGGCCGCATGGCTTTTGCACCGGGCAAAAATGGAAAAGAG
CGCCACACTGCGCCTTGGTGTTACACAAGAAATTCTGGCCCGCCTCATGGGCATCAGCCGGGAGAGCCTCAGCCGCGAAC
TTTCGGCCCTTTCGGCCGCAGGCATCATAGAGCATCAGCGGCGCAGCATCACCCTGCTGGACCACGAAGCCCTGAAACTG
CGGGCGCAAGGCTAG

Upstream 100 bases:

>100_bases
CACTGCCGCTGCCGCGCGCGTACACCGGAAGGTTTCGGCTGCTGCCGTACCGCCTCCGAAGTCCGGCATTCCTGAAGCCG
AAAGCCCGGGAGATTGTACT

Downstream 100 bases:

>100_bases
AGCTGTTCATGCGCGCGGCAAGCGCCGGGGCAACGGCCTTCACACCGCGAAACAACATTTTTTCAAAGCTGAAAATCCGT
AAAGGGCAACTATGCGCGTC

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; DnrE Protein; Transcription Regulator

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MTNRQYAANTDSLMNEESLQAAPTVADALCTGLLAGLNHHERDVLARHARLQSFAPGVALFQEGDESADAMLLLSGLVKL
CRHSSQGKECVLHLVHSGKFIDAGVLFYEGGLPISAVALQHTTVLSLNRRAFLHTLENNAPLAVSLLGAMSLRQRLLITK
IAGSQGRISVAGRVAAWLLHRAKMEKSATLRLGVTQEILARLMGISRESLSRELSALSAAGIIEHQRRSITLLDHEALKL
RAQG

Sequences:

>Translated_244_residues
MTNRQYAANTDSLMNEESLQAAPTVADALCTGLLAGLNHHERDVLARHARLQSFAPGVALFQEGDESADAMLLLSGLVKL
CRHSSQGKECVLHLVHSGKFIDAGVLFYEGGLPISAVALQHTTVLSLNRRAFLHTLENNAPLAVSLLGAMSLRQRLLITK
IAGSQGRISVAGRVAAWLLHRAKMEKSATLRLGVTQEILARLMGISRESLSRELSALSAAGIIEHQRRSITLLDHEALKL
RAQG
>Mature_243_residues
TNRQYAANTDSLMNEESLQAAPTVADALCTGLLAGLNHHERDVLARHARLQSFAPGVALFQEGDESADAMLLLSGLVKLC
RHSSQGKECVLHLVHSGKFIDAGVLFYEGGLPISAVALQHTTVLSLNRRAFLHTLENNAPLAVSLLGAMSLRQRLLITKI
AGSQGRISVAGRVAAWLLHRAKMEKSATLRLGVTQEILARLMGISRESLSRELSALSAAGIIEHQRRSITLLDHEALKLR
AQG

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 26362; Mature: 26231

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNRQYAANTDSLMNEESLQAAPTVADALCTGLLAGLNHHERDVLARHARLQSFAPGVAL
CCCCCCCCCCHHHHCHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHH
FQEGDESADAMLLLSGLVKLCRHSSQGKECVLHLVHSGKFIDAGVLFYEGGLPISAVALQ
HHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEECCEEEEECCCCHHHHHHH
HTTVLSLNRRAFLHTLENNAPLAVSLLGAMSLRQRLLITKIAGSQGRISVAGRVAAWLLH
HHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHH
RAKMEKSATLRLGVTQEILARLMGISRESLSRELSALSAAGIIEHQRRSITLLDHEALKL
HHHHCCCCEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHEE
RAQG
ECCC
>Mature Secondary Structure 
TNRQYAANTDSLMNEESLQAAPTVADALCTGLLAGLNHHERDVLARHARLQSFAPGVAL
CCCCCCCCCHHHHCHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHH
FQEGDESADAMLLLSGLVKLCRHSSQGKECVLHLVHSGKFIDAGVLFYEGGLPISAVALQ
HHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEECCEEEEECCCCHHHHHHH
HTTVLSLNRRAFLHTLENNAPLAVSLLGAMSLRQRLLITKIAGSQGRISVAGRVAAWLLH
HHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHH
RAKMEKSATLRLGVTQEILARLMGISRESLSRELSALSAAGIIEHQRRSITLLDHEALKL
HHHHCCCCEEEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHEE
RAQG
ECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA