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The map label for this gene is yaeL [C]

Identifier: 220903792

GI number: 220903792

Start: 625019

End: 626209

Strand: Reverse

Name: yaeL [C]

Synonym: Ddes_0515

Alternate gene names: 220903792

Gene position: 626209-625019 (Counterclockwise)

Preceding gene: 220903793

Following gene: 220903791

Centisome position: 21.79

GC content: 61.8

Gene sequence:

>1191_bases
ATGCTGACGACCATTATAGCAGTCACCCTTGTTCTTGGCGGCCTCATCTTTTTTCACGAGCTGGGGCATTTTGCCGTGGC
CCGTGGATTCGGCATGGGTGTTTCCACTTTTTCCCTTGGTTTCGGACCCAAAATTCTCAAACGCAAATGGGGCAAAACAG
AGTATGCCCTGTCCCTGATTCCCCTGGGCGGCTACGTGGCCCTGGTGGGCGAACAGGACGACAGCGAACTGCCCGAGGGC
TTTACCCGTGAAGAAAGTTTTTCTCTGCGCCCCGCGTGGCAACGCCTGCTGGTGGTGGCTGCCGGCCCTGTAGCCAACAT
GCTGCTGGCCTGGCTGCTGTGCTGGATACTGGCTTTCGGCTGGGGCACGCCCCAGTTGCTGCCCCAGGTGGGCGGCCTTG
TGGAGGACGGCCCCGCCGCCAGAGCCGGCGTTGAGGCCGGCGACACCATCGTGAGCATCAATGGTCAGCCCATTGTGGAT
TGGGAAGACATGACCCGCGCCATTGCCGCCAGCGACGGGCAGGCCATGCTCGTGAAGCTCAAGCGGCCCCACAGGGCGGA
AAGCGTCGCTCCCCAGGCGGATGAAGGCGCCACCGCGCAAGGCAGCCATGCCCAGACAGCGGCCAACGGCGACGCCATCG
CGCCCGCAAGCCTGCTGACGGTGGAAATCAGGCCTGAAATGGCCGTGCGCAAAACCATATTCGGTGAGGATGAAAAAGCC
TGGCTTGTGGGGATACGCAATACCGGCGCTGTACGCCTTGTGGAGCACGGCTTCTGGGGCGCTGCTGTGGCCGGGGCAAG
CCAGACTTCAAACATGCTTGCCCTGACCTGGAAAAGTTTTGTAAAGCTGGTTGAACGGGTGGTTCCCCTTGATCAGGTGG
GCGGTCCCATCATGATCATGCAGATGGTGGGCAAACAGGCCCATGAAGGCATGGCCGGGCTGCTGGCCCTGGCCGCGCTT
ATCAGCATCAACCTCGGGGTACTCAACCTCCTGCCCATTCCCGTGCTTGACGGCGGCCAGATCGTCTTTTGCCTGTGGGA
AATGATCTTCCGCCGCCCGGTCAACGCCAGGGTGCAGGACTATGCCATGCGGGCCGGGCTGGCCCTGCTGGTCACACTCA
TGCTGCTGGCCACCTACAATGACATCTGGCGCATAGTAAAGGGGGCCGGCTGGTTCGGGAGCGGATCATGA

Upstream 100 bases:

>100_bases
CCCTGCAAAGCGAGGCCCATACCCTGGCGGAGCGCATCACGCAGCTTGACAGCCAGAGCCGCGAGCTGGTGCGCAAGCTG
GCCCGCGACGGAGAATCCGC

Downstream 100 bases:

>100_bases
GCGCATATTCCACCGGGCTTGAGCTTATTCTCAATGCGGCCGAGGGCGTGTTGCAGATCATTGTCACGGATGACGAAAAA
CTGCTCTGCGCCCAGGAATG

Product: membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MLTTIIAVTLVLGGLIFFHELGHFAVARGFGMGVSTFSLGFGPKILKRKWGKTEYALSLIPLGGYVALVGEQDDSELPEG
FTREESFSLRPAWQRLLVVAAGPVANMLLAWLLCWILAFGWGTPQLLPQVGGLVEDGPAARAGVEAGDTIVSINGQPIVD
WEDMTRAIAASDGQAMLVKLKRPHRAESVAPQADEGATAQGSHAQTAANGDAIAPASLLTVEIRPEMAVRKTIFGEDEKA
WLVGIRNTGAVRLVEHGFWGAAVAGASQTSNMLALTWKSFVKLVERVVPLDQVGGPIMIMQMVGKQAHEGMAGLLALAAL
ISINLGVLNLLPIPVLDGGQIVFCLWEMIFRRPVNARVQDYAMRAGLALLVTLMLLATYNDIWRIVKGAGWFGSGS

Sequences:

>Translated_396_residues
MLTTIIAVTLVLGGLIFFHELGHFAVARGFGMGVSTFSLGFGPKILKRKWGKTEYALSLIPLGGYVALVGEQDDSELPEG
FTREESFSLRPAWQRLLVVAAGPVANMLLAWLLCWILAFGWGTPQLLPQVGGLVEDGPAARAGVEAGDTIVSINGQPIVD
WEDMTRAIAASDGQAMLVKLKRPHRAESVAPQADEGATAQGSHAQTAANGDAIAPASLLTVEIRPEMAVRKTIFGEDEKA
WLVGIRNTGAVRLVEHGFWGAAVAGASQTSNMLALTWKSFVKLVERVVPLDQVGGPIMIMQMVGKQAHEGMAGLLALAAL
ISINLGVLNLLPIPVLDGGQIVFCLWEMIFRRPVNARVQDYAMRAGLALLVTLMLLATYNDIWRIVKGAGWFGSGS
>Mature_396_residues
MLTTIIAVTLVLGGLIFFHELGHFAVARGFGMGVSTFSLGFGPKILKRKWGKTEYALSLIPLGGYVALVGEQDDSELPEG
FTREESFSLRPAWQRLLVVAAGPVANMLLAWLLCWILAFGWGTPQLLPQVGGLVEDGPAARAGVEAGDTIVSINGQPIVD
WEDMTRAIAASDGQAMLVKLKRPHRAESVAPQADEGATAQGSHAQTAANGDAIAPASLLTVEIRPEMAVRKTIFGEDEKA
WLVGIRNTGAVRLVEHGFWGAAVAGASQTSNMLALTWKSFVKLVERVVPLDQVGGPIMIMQMVGKQAHEGMAGLLALAAL
ISINLGVLNLLPIPVLDGGQIVFCLWEMIFRRPVNARVQDYAMRAGLALLVTLMLLATYNDIWRIVKGAGWFGSGS

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=450, Percent_Identity=29.3333333333333, Blast_Score=115, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 42343; Mature: 42343

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTTIIAVTLVLGGLIFFHELGHFAVARGFGMGVSTFSLGFGPKILKRKWGKTEYALSLI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEECCCCHHHHHHHCCCCEEEEEEE
PLGGYVALVGEQDDSELPEGFTREESFSLRPAWQRLLVVAAGPVANMLLAWLLCWILAFG
ECCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
WGTPQLLPQVGGLVEDGPAARAGVEAGDTIVSINGQPIVDWEDMTRAIAASDGQAMLVKL
CCCHHHHHHHCCCCCCCCCHHCCCCCCCEEEEECCCEEECHHHHHHHHHCCCCCEEEEEE
KRPHRAESVAPQADEGATAQGSHAQTAANGDAIAPASLLTVEIRPEMAVRKTIFGEDEKA
CCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCCCE
WLVGIRNTGAVRLVEHGFWGAAVAGASQTSNMLALTWKSFVKLVERVVPLDQVGGPIMIM
EEEEECCCCEEEEEECCCCHHHHCCCCCCCCEEEHHHHHHHHHHHHHCCHHHCCCHHHHH
QMVGKQAHEGMAGLLALAALISINLGVLNLLPIPVLDGGQIVFCLWEMIFRRPVNARVQD
HHHHHHHHCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHH
YAMRAGLALLVTLMLLATYNDIWRIVKGAGWFGSGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLTTIIAVTLVLGGLIFFHELGHFAVARGFGMGVSTFSLGFGPKILKRKWGKTEYALSLI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEECCCCHHHHHHHCCCCEEEEEEE
PLGGYVALVGEQDDSELPEGFTREESFSLRPAWQRLLVVAAGPVANMLLAWLLCWILAFG
ECCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
WGTPQLLPQVGGLVEDGPAARAGVEAGDTIVSINGQPIVDWEDMTRAIAASDGQAMLVKL
CCCHHHHHHHCCCCCCCCCHHCCCCCCCEEEEECCCEEECHHHHHHHHHCCCCCEEEEEE
KRPHRAESVAPQADEGATAQGSHAQTAANGDAIAPASLLTVEIRPEMAVRKTIFGEDEKA
CCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCCCE
WLVGIRNTGAVRLVEHGFWGAAVAGASQTSNMLALTWKSFVKLVERVVPLDQVGGPIMIM
EEEEECCCCEEEEEECCCCHHHHCCCCCCCCEEEHHHHHHHHHHHHHCCHHHCCCHHHHH
QMVGKQAHEGMAGLLALAALISINLGVLNLLPIPVLDGGQIVFCLWEMIFRRPVNARVQD
HHHHHHHHCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHHH
YAMRAGLALLVTLMLLATYNDIWRIVKGAGWFGSGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]