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The map label for this gene is moaC

Identifier: 220903777

GI number: 220903777

Start: 607629

End: 608120

Strand: Reverse

Name: moaC

Synonym: Ddes_0500

Alternate gene names: 220903777

Gene position: 608120-607629 (Counterclockwise)

Preceding gene: 220903778

Following gene: 220903776

Centisome position: 21.16

GC content: 61.18

Gene sequence:

>492_bases
ATGAACAGCAGTTTTTCGCATCTGGATGGGCAGGGCAATGTGACCATGGTGGACGTTGGAGGCAAGCAGGCCACAGAGCG
CGTGGCCATTGCCGAAGCGGTGGTGGAACTGCGCCCCGCAACCCTCGAGCTTCTGCTCAAGGTGGCCCTGCCCAAGGGCG
ACGTACTCACCTGCGCCAAAATCGGCGGCATCATGGCTGCCAAGCGCGTTGGCGAGATTATTCCCCTGTGCCATCCGCTG
AGCCTCACCTATGCCGACATCCGCTTTGAAGTAAGCGAAGCGCCGCCGCGCATCCGCATTGAGGCCGAAACCCGCACCGT
GGGCAATACCGGCGTGGAGATGGAAGCCATCGTGGCCGCGCAAACCGCTGCAGCCGTTATTTACGACATGTGCAAGGCCG
TGCAGCGCGATATCATCATCAGCCGGGTGCGCCTGCTGCACAAGCGCGGCGGCAAAAGCGGCGAATTCAACGCGCCTGAT
ATGGAAGAATGA

Upstream 100 bases:

>100_bases
CACCCGGGATTCTAGACTGGCTGGCCGGGCTGCGCTGAGGCTACCCCGCCGGGCGGCCACAATCGCCCATACACGTTACA
ACAATGCCGACGAGGTGTTT

Downstream 100 bases:

>100_bases
TGCTGCCTTACATTGATCCCGTTGCTTTCAGCATTGGCAACCTGCAGTTGCGCTGGTATGGACTCATGTATCTGGCGGGC
TTTGGCCTGGGCTGGTGGCT

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MNSSFSHLDGQGNVTMVDVGGKQATERVAIAEAVVELRPATLELLLKVALPKGDVLTCAKIGGIMAAKRVGEIIPLCHPL
SLTYADIRFEVSEAPPRIRIEAETRTVGNTGVEMEAIVAAQTAAAVIYDMCKAVQRDIIISRVRLLHKRGGKSGEFNAPD
MEE

Sequences:

>Translated_163_residues
MNSSFSHLDGQGNVTMVDVGGKQATERVAIAEAVVELRPATLELLLKVALPKGDVLTCAKIGGIMAAKRVGEIIPLCHPL
SLTYADIRFEVSEAPPRIRIEAETRTVGNTGVEMEAIVAAQTAAAVIYDMCKAVQRDIIISRVRLLHKRGGKSGEFNAPD
MEE
>Mature_163_residues
MNSSFSHLDGQGNVTMVDVGGKQATERVAIAEAVVELRPATLELLLKVALPKGDVLTCAKIGGIMAAKRVGEIIPLCHPL
SLTYADIRFEVSEAPPRIRIEAETRTVGNTGVEMEAIVAAQTAAAVIYDMCKAVQRDIIISRVRLLHKRGGKSGEFNAPD
MEE

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=155, Percent_Identity=49.6774193548387, Blast_Score=151, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=38.9261744966443, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28574490, Length=150, Percent_Identity=50, Blast_Score=147, Evalue=2e-36,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=50.3649635036496, Blast_Score=135, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_DESDA (B8J4F3)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002479089.1
- GeneID:   7284167
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_0500
- HOGENOM:   HBG605231
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17511; Mature: 17511

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: ACT_SITE 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSFSHLDGQGNVTMVDVGGKQATERVAIAEAVVELRPATLELLLKVALPKGDVLTCAK
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEHHHH
IGGIMAAKRVGEIIPLCHPLSLTYADIRFEVSEAPPRIRIEAETRTVGNTGVEMEAIVAA
HHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCEEEEEECCEECCCCCCCHHHHHHH
QTAAAVIYDMCKAVQRDIIISRVRLLHKRGGKSGEFNAPDMEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNSSFSHLDGQGNVTMVDVGGKQATERVAIAEAVVELRPATLELLLKVALPKGDVLTCAK
CCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEHHHH
IGGIMAAKRVGEIIPLCHPLSLTYADIRFEVSEAPPRIRIEAETRTVGNTGVEMEAIVAA
HHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCEEEEEECCEECCCCCCCHHHHHHH
QTAAAVIYDMCKAVQRDIIISRVRLLHKRGGKSGEFNAPDMEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA