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The map label for this gene is rpe [H]

Identifier: 220903759

GI number: 220903759

Start: 590935

End: 591663

Strand: Reverse

Name: rpe [H]

Synonym: Ddes_0481

Alternate gene names: 220903759

Gene position: 591663-590935 (Counterclockwise)

Preceding gene: 220903761

Following gene: 220903758

Centisome position: 20.59

GC content: 62.28

Gene sequence:

>729_bases
ATGATTCTATCACCCTCGCTGCTTTCCGCCGATTTTTCCCGCCTGGCCGAAGAGTTGCAAGCTCTTGAGGCCGCCGGGGT
TACCTGGCTGCACCTTGATGTGATGGACGGGGCCTTTGTACCCAACATCACCTTTGGTCCCCCGCTGATCAAGGCCCTGA
GGCCCGGCAGCGGGCTTTTTTTTGACGTGCATCTCATGGTGGAAAACCCCGCCCGCTATATCCAGGACTTCAGGGACGCG
GGGGCGGATATGCTTGTTATTCATACAGAGGCCGACCGCCACCCGCAGCGCACGCTTGCCGCCATCCGCGACATGGGCTG
CCGCGCGGGCGTGGCGCTGAACCCCGGCACAGACCTTGGCGCCATACGCTGGCTTGTCAATGATCTGGACATGCTGCTCG
TCATGAGCGTCAACCCCGGCTTTTCCGGCCAGGCCTTCATTCCCGCCACCTTTGACAAGGTCCGCAGTGCCCGCCGCCTG
CTGGATGCCTGCGGCGGCGAAGATGTTCTTATTCAGGTGGACGGTGGCGTATGCCCCGAAAATACGGCCCAGCTGGTAGA
AGCCGGGGCCGACGTGCTGGTGTCAGGCTCGGCCTTTTTCGGGCACAAGCCCTATGACGCCCGCCTGGCGGCCTTCATGA
AATCTCTGGACGGCCGCGAGCAGCGCCCCGCGCTGCAAAAGGCCGCCCGGCGTCAGACCTTTGCCCTTACTCATCCCAAG
CAAAAATAG

Upstream 100 bases:

>100_bases
GGGAAGGCGACTCCTTTGCACACGGCGGCCGGGTCAGTCAGACTCTGCGGACGGCCAAGCCCGAAGGCCCTTCCCCATAA
CACAAGACAGAACTACTCCC

Downstream 100 bases:

>100_bases
AGGAATGATCATGCCCACCCGCAGACAGTGCGCCAACGCCATCCGCGCCCTTGCCATGGACGCTATTGAGAAAGCCCGCT
CCGGCCACCCCGGTGCGCCC

Product: Ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MILSPSLLSADFSRLAEELQALEAAGVTWLHLDVMDGAFVPNITFGPPLIKALRPGSGLFFDVHLMVENPARYIQDFRDA
GADMLVIHTEADRHPQRTLAAIRDMGCRAGVALNPGTDLGAIRWLVNDLDMLLVMSVNPGFSGQAFIPATFDKVRSARRL
LDACGGEDVLIQVDGGVCPENTAQLVEAGADVLVSGSAFFGHKPYDARLAAFMKSLDGREQRPALQKAARRQTFALTHPK
QK

Sequences:

>Translated_242_residues
MILSPSLLSADFSRLAEELQALEAAGVTWLHLDVMDGAFVPNITFGPPLIKALRPGSGLFFDVHLMVENPARYIQDFRDA
GADMLVIHTEADRHPQRTLAAIRDMGCRAGVALNPGTDLGAIRWLVNDLDMLLVMSVNPGFSGQAFIPATFDKVRSARRL
LDACGGEDVLIQVDGGVCPENTAQLVEAGADVLVSGSAFFGHKPYDARLAAFMKSLDGREQRPALQKAARRQTFALTHPK
QK
>Mature_242_residues
MILSPSLLSADFSRLAEELQALEAAGVTWLHLDVMDGAFVPNITFGPPLIKALRPGSGLFFDVHLMVENPARYIQDFRDA
GADMLVIHTEADRHPQRTLAAIRDMGCRAGVALNPGTDLGAIRWLVNDLDMLLVMSVNPGFSGQAFIPATFDKVRSARRL
LDACGGEDVLIQVDGGVCPENTAQLVEAGADVLVSGSAFFGHKPYDARLAAFMKSLDGREQRPALQKAARRQTFALTHPK
QK

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=200, Percent_Identity=40.5, Blast_Score=154, Evalue=9e-38,
Organism=Homo sapiens, GI219879828, Length=200, Percent_Identity=38, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI24307923, Length=156, Percent_Identity=32.6923076923077, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1789788, Length=205, Percent_Identity=46.8292682926829, Blast_Score=190, Evalue=7e-50,
Organism=Escherichia coli, GI1790523, Length=204, Percent_Identity=34.8039215686275, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790754, Length=212, Percent_Identity=34.9056603773585, Blast_Score=115, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17552948, Length=203, Percent_Identity=43.8423645320197, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6322341, Length=235, Percent_Identity=39.5744680851064, Blast_Score=166, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24586301, Length=200, Percent_Identity=40.5, Blast_Score=155, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 26237; Mature: 26237

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILSPSLLSADFSRLAEELQALEAAGVTWLHLDVMDGAFVPNITFGPPLIKALRPGSGLF
CCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCE
FDVHLMVENPARYIQDFRDAGADMLVIHTEADRHPQRTLAAIRDMGCRAGVALNPGTDLG
EEEEEEECCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEECCCCCHH
AIRWLVNDLDMLLVMSVNPGFSGQAFIPATFDKVRSARRLLDACGGEDVLIQVDGGVCPE
HHHHHHHHHCEEEEEECCCCCCCCEECCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
NTAQLVEAGADVLVSGSAFFGHKPYDARLAAFMKSLDGREQRPALQKAARRQTFALTHPK
HHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCEEEECCCC
QK
CC
>Mature Secondary Structure
MILSPSLLSADFSRLAEELQALEAAGVTWLHLDVMDGAFVPNITFGPPLIKALRPGSGLF
CCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCE
FDVHLMVENPARYIQDFRDAGADMLVIHTEADRHPQRTLAAIRDMGCRAGVALNPGTDLG
EEEEEEECCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEECCCCCHH
AIRWLVNDLDMLLVMSVNPGFSGQAFIPATFDKVRSARRLLDACGGEDVLIQVDGGVCPE
HHHHHHHHHCEEEEEECCCCCCCCEECCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
NTAQLVEAGADVLVSGSAFFGHKPYDARLAAFMKSLDGREQRPALQKAARRQTFALTHPK
HHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCEEEECCCC
QK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231; 9298645 [H]