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The map label for this gene is ssb [H]

Identifier: 220903733

GI number: 220903733

Start: 550814

End: 551338

Strand: Reverse

Name: ssb [H]

Synonym: Ddes_0455

Alternate gene names: 220903733

Gene position: 551338-550814 (Counterclockwise)

Preceding gene: 220903734

Following gene: 220903732

Centisome position: 19.19

GC content: 61.9

Gene sequence:

>525_bases
ATGCTTAATAAAGTCATGATCATCGGCCGCCTGGGGCGCGACCCCGAATTGCGCTACACCCAGAGCGGCTCGCCTGTGGC
TAGCCTCAATATAGCCACCGACGAATCCTATACCGACCGCGACGGCAACAAGGTGGACCGCACCGAATGGCATCGCGTAT
CCGTTTTTCAGCGCCAGGCCGAAAACTGTGCCAACTACCTGACCAAAGGCAGCCTTGTGTACGTGGAAGGTAGCCTGCAG
ACTCGCAAATGGCAGGATCAGCAGGGGCAGGACCGCTATACCACAGAAATCAAGGCCCAGCGCGTGCAGTTTCTTGACCG
CAAAGGCGATGCCCCGCGCGGTGAAGGCAGCGGCGGACGCGGCTATGAGGACGATTACGGCGCTGCTGCGCCCCGCGGCA
ATGCCCCCCGTGGCGGCCAGGGTGCTCCGCGCCAGCAGAGCCAGGGCAACCGCAGACCTGCGGATGACGACCTTGGCCCG
GCCTTTCCTTCTGAGGCCTCCAATATGGATGAAGTCCCCTTCTAG

Upstream 100 bases:

>100_bases
AATATTTTAAGTGACAAACTTGAAGACGTGCTGGATACTCTTGAAAAGGCCTTTGTGGCCTGAGATATCCGGAACAAGCA
GTATTATCGGAGACTTTCAC

Downstream 100 bases:

>100_bases
AGCATTCAGCCTTTGAGAATATACGTTCTTAAGGTTAAGGCACGCTCTTACGGCGGACGGCAGATCACGCAGCCATCGGC
GCAATCTGCCTTTGAGCGCA

Product: single-strand binding protein

Products: NA

Alternate protein names: SSB; Helix-destabilizing protein [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MLNKVMIIGRLGRDPELRYTQSGSPVASLNIATDESYTDRDGNKVDRTEWHRVSVFQRQAENCANYLTKGSLVYVEGSLQ
TRKWQDQQGQDRYTTEIKAQRVQFLDRKGDAPRGEGSGGRGYEDDYGAAAPRGNAPRGGQGAPRQQSQGNRRPADDDLGP
AFPSEASNMDEVPF

Sequences:

>Translated_174_residues
MLNKVMIIGRLGRDPELRYTQSGSPVASLNIATDESYTDRDGNKVDRTEWHRVSVFQRQAENCANYLTKGSLVYVEGSLQ
TRKWQDQQGQDRYTTEIKAQRVQFLDRKGDAPRGEGSGGRGYEDDYGAAAPRGNAPRGGQGAPRQQSQGNRRPADDDLGP
AFPSEASNMDEVPF
>Mature_174_residues
MLNKVMIIGRLGRDPELRYTQSGSPVASLNIATDESYTDRDGNKVDRTEWHRVSVFQRQAENCANYLTKGSLVYVEGSLQ
TRKWQDQQGQDRYTTEIKAQRVQFLDRKGDAPRGEGSGGRGYEDDYGAAAPRGNAPRGGQGAPRQQSQGNRRPADDDLGP
AFPSEASNMDEVPF

Specific function: This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair [H]

COG id: COG0629

COG function: function code L; Single-stranded DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SSB domain [H]

Homologues:

Organism=Homo sapiens, GI4507231, Length=111, Percent_Identity=35.1351351351351, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1790494, Length=97, Percent_Identity=54.639175257732, Blast_Score=116, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17554374, Length=108, Percent_Identity=38.8888888888889, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI85725234, Length=105, Percent_Identity=38.0952380952381, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24647376, Length=105, Percent_Identity=38.0952380952381, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: 1622 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000424
- InterPro:   IPR011344 [H]

Pfam domain/function: PF00436 SSB [H]

EC number: NA

Molecular weight: Translated: 19297; Mature: 19297

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50935 SSB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNKVMIIGRLGRDPELRYTQSGSPVASLNIATDESYTDRDGNKVDRTEWHRVSVFQRQA
CCCCEEEEEECCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ENCANYLTKGSLVYVEGSLQTRKWQDQQGQDRYTTEIKAQRVQFLDRKGDAPRGEGSGGR
HHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GYEDDYGAAAPRGNAPRGGQGAPRQQSQGNRRPADDDLGPAFPSEASNMDEVPF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLNKVMIIGRLGRDPELRYTQSGSPVASLNIATDESYTDRDGNKVDRTEWHRVSVFQRQA
CCCCEEEEEECCCCCCEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ENCANYLTKGSLVYVEGSLQTRKWQDQQGQDRYTTEIKAQRVQFLDRKGDAPRGEGSGGR
HHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GYEDDYGAAAPRGNAPRGGQGAPRQQSQGNRRPADDDLGPAFPSEASNMDEVPF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]