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The map label for this gene is sat

Identifier: 220903732

GI number: 220903732

Start: 548418

End: 549689

Strand: Reverse

Name: sat

Synonym: Ddes_0454

Alternate gene names: 220903732

Gene position: 549689-548418 (Counterclockwise)

Preceding gene: 220903733

Following gene: 220903731

Centisome position: 19.13

GC content: 58.81

Gene sequence:

>1272_bases
ATGTCCAAGTTGGTAGCTCCTCACGGCGGTAAGGGTCTGGTCTGTTGCCTGCTTGAAGGCAAGGCCCTGGAAGATGAAAA
GAAAAAGGCCGCTGGCCTCAAGCAGATCGAAATTTCTTCCCGCGCCAAGGGCGACCTCATCATGATGGGCATTGGCGGCT
TTTCGCCTCTGAACGGTTTCATGAACAAGGCCGACTGGAAGAGCGTGTGCGAAAAAATGACCCTCACCGACGGCACCTTC
TGGCCCGTGCCCGTAACCCTTGACGTCTCCGCTGCCGAAGCCAAGAGCATCAAGGCCGGTGAAGAAGTGGCCCTGGTCCG
CAAGGGCGAAGTCATGGCCACCATGAAGGTCGAAGAAATCTATGAAATGACCGAAGCCGACAAAAAGATGGAGTGCGAGC
TGGTCTTCAAGGGCGAAGGCCCTGACTCTGAAAAATTCTGGGAAGTGGCCCCCGAAGACCATCCCGGCGTGAAAATGGTT
CTGGCCCAGAAAGAATACAATATCGCCGGTCCCGTCAAAGTGCTCTCGCAGGGCGAATTCCCCGAGAAATTCCCCGGCGT
GTACATGACCCCCGCCCAGCTGCGCGCCAAGATGGACGAACGCGGCTGGCAGAAGGTTGCCGCCCTGCAGCTGCGCAACC
CCATGCACCGCTCGCATGAATACCTTGCCAAAATCGGCGTGGAAGTGTGCGACGGCGTGGTCATCCACTCCCTGGTCGGC
TCCCTGAAGCCCGGCGACATCCCGGCCGAAGTGCGCGTGAAGTGCATCGACACCCTGGTGGACAAGTACTTTGTGAAAGA
CTTTGTCATCCAGGCCGGTTACCCCCTGGACATGCGCTATGCCGGCCCGCGTGAAGCCCTGCTGCACGCCACCTTCCGTC
AGAACTACGGCATCAACAACCTGCTGGTGGGTCGCGACCACGCCGGTGTGGGCGACTTCTACGGCATGTTTGAAGCCCAG
GAAATCTTCCGCAAGATGCCTACCCCCGCAGATTCCGGCAAGCGCCTGCTCTGCGAACCCCTGAACATTGACTGGACCTT
CTACTGCAAGAAGTGCGACGGCATGGCCAGCATGCGCACCTGCCCGCACGGCAAGGAAGACCGCGTCATCCTGTCCGGCA
CCAAGCTGCGCAAGATGCTTTCTGAAGGCGCGGATGTACCGGATCACTTTGGCCGCGATGAAGTGCTCGCCATCCTGCGC
GAATACTACTCCGGTCTTACCGAAAAAGTCGAAGTCAAGATGCAGCGTGCCGCCTCTGGTTCCACCATGTAA

Upstream 100 bases:

>100_bases
ATTATTCACAAGATGGATTTCGAAAGAAGCCCTCCCCATTTCGGCTGTGCGTGCTGCCGTTGCGGGAGGCTGTCATAACC
AAAACACGGAGGATTTCGCG

Downstream 100 bases:

>100_bases
GGTTGCCGCAGTCACAACGCGAAAGGACGTCCGCAAGGGCGTCCTTTTGTTTTGCCCTGCATGCCTTGCAGCCACACCAT
GCTTTACCTGAAGGCAAAAA

Product: sulfate adenylyltransferase

Products: NA

Alternate protein names: ATP-sulfurylase; Sulfate adenylate transferase; SAT

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MSKLVAPHGGKGLVCCLLEGKALEDEKKKAAGLKQIEISSRAKGDLIMMGIGGFSPLNGFMNKADWKSVCEKMTLTDGTF
WPVPVTLDVSAAEAKSIKAGEEVALVRKGEVMATMKVEEIYEMTEADKKMECELVFKGEGPDSEKFWEVAPEDHPGVKMV
LAQKEYNIAGPVKVLSQGEFPEKFPGVYMTPAQLRAKMDERGWQKVAALQLRNPMHRSHEYLAKIGVEVCDGVVIHSLVG
SLKPGDIPAEVRVKCIDTLVDKYFVKDFVIQAGYPLDMRYAGPREALLHATFRQNYGINNLLVGRDHAGVGDFYGMFEAQ
EIFRKMPTPADSGKRLLCEPLNIDWTFYCKKCDGMASMRTCPHGKEDRVILSGTKLRKMLSEGADVPDHFGRDEVLAILR
EYYSGLTEKVEVKMQRAASGSTM

Sequences:

>Translated_423_residues
MSKLVAPHGGKGLVCCLLEGKALEDEKKKAAGLKQIEISSRAKGDLIMMGIGGFSPLNGFMNKADWKSVCEKMTLTDGTF
WPVPVTLDVSAAEAKSIKAGEEVALVRKGEVMATMKVEEIYEMTEADKKMECELVFKGEGPDSEKFWEVAPEDHPGVKMV
LAQKEYNIAGPVKVLSQGEFPEKFPGVYMTPAQLRAKMDERGWQKVAALQLRNPMHRSHEYLAKIGVEVCDGVVIHSLVG
SLKPGDIPAEVRVKCIDTLVDKYFVKDFVIQAGYPLDMRYAGPREALLHATFRQNYGINNLLVGRDHAGVGDFYGMFEAQ
EIFRKMPTPADSGKRLLCEPLNIDWTFYCKKCDGMASMRTCPHGKEDRVILSGTKLRKMLSEGADVPDHFGRDEVLAILR
EYYSGLTEKVEVKMQRAASGSTM
>Mature_422_residues
SKLVAPHGGKGLVCCLLEGKALEDEKKKAAGLKQIEISSRAKGDLIMMGIGGFSPLNGFMNKADWKSVCEKMTLTDGTFW
PVPVTLDVSAAEAKSIKAGEEVALVRKGEVMATMKVEEIYEMTEADKKMECELVFKGEGPDSEKFWEVAPEDHPGVKMVL
AQKEYNIAGPVKVLSQGEFPEKFPGVYMTPAQLRAKMDERGWQKVAALQLRNPMHRSHEYLAKIGVEVCDGVVIHSLVGS
LKPGDIPAEVRVKCIDTLVDKYFVKDFVIQAGYPLDMRYAGPREALLHATFRQNYGINNLLVGRDHAGVGDFYGMFEAQE
IFRKMPTPADSGKRLLCEPLNIDWTFYCKKCDGMASMRTCPHGKEDRVILSGTKLRKMLSEGADVPDHFGRDEVLAILRE
YYSGLTEKVEVKMQRAASGSTM

Specific function: Unknown

COG id: COG2046

COG function: function code P; ATP sulfurylase (sulfate adenylyltransferase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfate adenylyltransferase family

Homologues:

Organism=Homo sapiens, GI62912492, Length=406, Percent_Identity=25.8620689655172, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI34447231, Length=401, Percent_Identity=25.6857855361596, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI46094058, Length=397, Percent_Identity=25.4408060453401, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17542422, Length=413, Percent_Identity=25.4237288135593, Blast_Score=108, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6322469, Length=413, Percent_Identity=34.6246973365617, Blast_Score=221, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24667040, Length=414, Percent_Identity=26.8115942028986, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24667032, Length=414, Percent_Identity=26.8115942028986, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24667028, Length=414, Percent_Identity=26.8115942028986, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24667036, Length=414, Percent_Identity=26.8115942028986, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI116007838, Length=414, Percent_Identity=26.8115942028986, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24667044, Length=414, Percent_Identity=26.8115942028986, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SAT_DESDA (B8J4A8)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002479044.1
- GeneID:   7284119
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_0454
- HOGENOM:   HBG480761
- ProtClustDB:   CLSK904027
- HAMAP:   MF_00066
- InterPro:   IPR015947
- InterPro:   IPR014729
- InterPro:   IPR020792
- InterPro:   IPR002650
- Gene3D:   G3DSA:3.40.50.620
- TIGRFAMs:   TIGR00339

Pfam domain/function: PF01747 ATP-sulfurylase; SSF88697 PUA-like

EC number: =2.7.7.4

Molecular weight: Translated: 46913; Mature: 46782

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLVAPHGGKGLVCCLLEGKALEDEKKKAAGLKQIEISSRAKGDLIMMGIGGFSPLNGF
CCCCCCCCCCCEEEEEEECCCCCCHHHHHHCCCEEEEECCCCCCCEEEEECCCCCHHHHH
MNKADWKSVCEKMTLTDGTFWPVPVTLDVSAAEAKSIKAGEEVALVRKGEVMATMKVEEI
HCCCHHHHHHHHHCCCCCCEECEEEEEECCHHHHHHCCCCCEEEEEECCCEEEEEEHHHH
YEMTEADKKMECELVFKGEGPDSEKFWEVAPEDHPGVKMVLAQKEYNIAGPVKVLSQGEF
HHHHHCCCCEEEEEEEECCCCCCCCCEECCCCCCCCEEEEEEECCCCCCCCHHHHCCCCC
PEKFPGVYMTPAQLRAKMDERGWQKVAALQLRNPMHRSHEYLAKIGVEVCDGVVIHSLVG
CCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLKPGDIPAEVRVKCIDTLVDKYFVKDFVIQAGYPLDMRYAGPREALLHATFRQNYGINN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCCCE
LLVGRDHAGVGDFYGMFEAQEIFRKMPTPADSGKRLLCEPLNIDWTFYCKKCDGMASMRT
EEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEECCCCCHHHHC
CPHGKEDRVILSGTKLRKMLSEGADVPDHFGRDEVLAILREYYSGLTEKVEVKMQRAASG
CCCCCCCCEEECCHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
STM
CCC
>Mature Secondary Structure 
SKLVAPHGGKGLVCCLLEGKALEDEKKKAAGLKQIEISSRAKGDLIMMGIGGFSPLNGF
CCCCCCCCCCEEEEEEECCCCCCHHHHHHCCCEEEEECCCCCCCEEEEECCCCCHHHHH
MNKADWKSVCEKMTLTDGTFWPVPVTLDVSAAEAKSIKAGEEVALVRKGEVMATMKVEEI
HCCCHHHHHHHHHCCCCCCEECEEEEEECCHHHHHHCCCCCEEEEEECCCEEEEEEHHHH
YEMTEADKKMECELVFKGEGPDSEKFWEVAPEDHPGVKMVLAQKEYNIAGPVKVLSQGEF
HHHHHCCCCEEEEEEEECCCCCCCCCEECCCCCCCCEEEEEEECCCCCCCCHHHHCCCCC
PEKFPGVYMTPAQLRAKMDERGWQKVAALQLRNPMHRSHEYLAKIGVEVCDGVVIHSLVG
CCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLKPGDIPAEVRVKCIDTLVDKYFVKDFVIQAGYPLDMRYAGPREALLHATFRQNYGINN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCCCE
LLVGRDHAGVGDFYGMFEAQEIFRKMPTPADSGKRLLCEPLNIDWTFYCKKCDGMASMRT
EEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEEEECCCCCHHHHC
CPHGKEDRVILSGTKLRKMLSEGADVPDHFGRDEVLAILREYYSGLTEKVEVKMQRAASG
CCCCCCCCEEECCHHHHHHHHCCCCCCHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
STM
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA