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The map label for this gene is xanB [H]

Identifier: 220903691

GI number: 220903691

Start: 503254

End: 504696

Strand: Reverse

Name: xanB [H]

Synonym: Ddes_0413

Alternate gene names: 220903691

Gene position: 504696-503254 (Counterclockwise)

Preceding gene: 220903692

Following gene: 220903690

Centisome position: 17.56

GC content: 60.57

Gene sequence:

>1443_bases
ATGCCAAGCATTGCTCCTGTCATACTCTGCGGCGGCAGCGGTACACGCCTGTGGCCGCTCTCACGCGAGACCTATCCCAA
GCAGTTTGTGGACCTGGGCGAGGGGCGTACCCTGTTCAAAGACACGCTCTTGCGGGCGCAACGTACTCCGGAAAGCCTGG
AACCGGTCATTGTCTGCAATGAGGCCCACCGTTTTTATGTAACGGCCGCATTGTACGAATGTGACGTTCGCGCCACCATT
CTTTTAGAACCCGCACCGCGCAATACCGCGCCGGCCATTGCTCTCGCGGCTCTCACCCTTGCCCGCGACGAAGCGGATCC
GCTCATGCTGGTGTTGCCGTCCGATCATGCCATCGGTAACGAAGCCGCCTTCTTCAAGGGAGTGGAGTCTGCCGCAGCCC
TGGCGGAACAAGGGCATATCGTCACTTTCGGCATCACACCCGCAAGCCCGGAAACAGGCTTTGGCTATATTGAACAGGGT
GAAACTTTGGGCTACGGCGGCTTCCGCGTGGCCCGCTTTGTGGAAAAACCCGATACAGCGGCGGCCCAATCCATGCTGGA
TCAGGGCGGCTTTTTGTGGAACAGCGGCATGTTTCTGTTGCGTGCCTCCGTGTACCTGAAAGAGCTTGAACGCTTCGCCC
CCGAAATACACGCCGCCTGCTGCACCGCCTGGCAAAGACGCGCAGCCGACGGCGCGTTCTGCCGCCCGGACGCGGACGCA
TTTCTGGCCTCGCCGTCCGACTCCATCGACTATGCAGTCATGGAGCAGACGGACCGTGCGGCGGTAGTTCCCCTGTCCAC
AGGCTGGAGCGACCTTGGCTCATGGGAGGCGTTCTATCAGGCGGAAGCGGGGGACGACAGCGGCAACGTCTGCCACGGCG
ACATCATGACCCAAGACGCGGAGAACTGTTATTTCAACGCCCAGCATCGCCTGGTGACGGCCATTGGCGTGCGCGACCTT
GTGGTTGTGGAAACACGCGATGCCGTGCTAGTGGCCCCGCGCGAGCGGGTGCAGGAGGTCAAGACCATGGTCGGCCGCCT
GCAATCAGCCCGGCGAACCGAATGCAGACAGCATCCGCTGGTCTACCGCCCCTGGGGCAGCTACGAAACGCTCGTTATGG
ACGGCCGTTTTCAGGTCAAACGTATCATAGTCAATCCAGGTGCGGAGCTTTCCCTCCAGATGCACCACCACCGCGCCGAG
CACTGGGTAGTTGTCAGCGGCACGGCCGAGGTGACCAACGGCAATGAAACCCGCCTGTATACAGAAAACCAGTCCACCTA
CATTCCCGTGGGAACGCGGCACAGGCTGAAAAACCCCGGCGTCATCCCCTTGGTGCTTATTGAAATCCAGTCCGGCGCAT
ATCTGGGCGAAGACGACATTGTGCGCTTTGCCGATGTGTACGGACGCGAAGATTTACCGGCGCACGGCAACGAAAACAGA
TGA

Upstream 100 bases:

>100_bases
CTGCACCTGCGATTAGTGTATCTTCCGGGCCGTGCGCCACAGCGGACGTACAGGCCCTGTGCGGTATAAAGCGCTTATTT
GAACACCTGTGAGTAATTCC

Downstream 100 bases:

>100_bases
AACCACCGGGTGGACATCGTCCACCATGCAATATAGAATTATAAGTTCACCTTGAGCAATCTGAACGTAAAAAATACTAT
GACAATTTGTCAGGTCAGGA

Product: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MPSIAPVILCGGSGTRLWPLSRETYPKQFVDLGEGRTLFKDTLLRAQRTPESLEPVIVCNEAHRFYVTAALYECDVRATI
LLEPAPRNTAPAIALAALTLARDEADPLMLVLPSDHAIGNEAAFFKGVESAAALAEQGHIVTFGITPASPETGFGYIEQG
ETLGYGGFRVARFVEKPDTAAAQSMLDQGGFLWNSGMFLLRASVYLKELERFAPEIHAACCTAWQRRAADGAFCRPDADA
FLASPSDSIDYAVMEQTDRAAVVPLSTGWSDLGSWEAFYQAEAGDDSGNVCHGDIMTQDAENCYFNAQHRLVTAIGVRDL
VVVETRDAVLVAPRERVQEVKTMVGRLQSARRTECRQHPLVYRPWGSYETLVMDGRFQVKRIIVNPGAELSLQMHHHRAE
HWVVVSGTAEVTNGNETRLYTENQSTYIPVGTRHRLKNPGVIPLVLIEIQSGAYLGEDDIVRFADVYGREDLPAHGNENR

Sequences:

>Translated_480_residues
MPSIAPVILCGGSGTRLWPLSRETYPKQFVDLGEGRTLFKDTLLRAQRTPESLEPVIVCNEAHRFYVTAALYECDVRATI
LLEPAPRNTAPAIALAALTLARDEADPLMLVLPSDHAIGNEAAFFKGVESAAALAEQGHIVTFGITPASPETGFGYIEQG
ETLGYGGFRVARFVEKPDTAAAQSMLDQGGFLWNSGMFLLRASVYLKELERFAPEIHAACCTAWQRRAADGAFCRPDADA
FLASPSDSIDYAVMEQTDRAAVVPLSTGWSDLGSWEAFYQAEAGDDSGNVCHGDIMTQDAENCYFNAQHRLVTAIGVRDL
VVVETRDAVLVAPRERVQEVKTMVGRLQSARRTECRQHPLVYRPWGSYETLVMDGRFQVKRIIVNPGAELSLQMHHHRAE
HWVVVSGTAEVTNGNETRLYTENQSTYIPVGTRHRLKNPGVIPLVLIEIQSGAYLGEDDIVRFADVYGREDLPAHGNENR
>Mature_479_residues
PSIAPVILCGGSGTRLWPLSRETYPKQFVDLGEGRTLFKDTLLRAQRTPESLEPVIVCNEAHRFYVTAALYECDVRATIL
LEPAPRNTAPAIALAALTLARDEADPLMLVLPSDHAIGNEAAFFKGVESAAALAEQGHIVTFGITPASPETGFGYIEQGE
TLGYGGFRVARFVEKPDTAAAQSMLDQGGFLWNSGMFLLRASVYLKELERFAPEIHAACCTAWQRRAADGAFCRPDADAF
LASPSDSIDYAVMEQTDRAAVVPLSTGWSDLGSWEAFYQAEAGDDSGNVCHGDIMTQDAENCYFNAQHRLVTAIGVRDLV
VVETRDAVLVAPRERVQEVKTMVGRLQSARRTECRQHPLVYRPWGSYETLVMDGRFQVKRIIVNPGAELSLQMHHHRAEH
WVVVSGTAEVTNGNETRLYTENQSTYIPVGTRHRLKNPGVIPLVLIEIQSGAYLGEDDIVRFADVYGREDLPAHGNENR

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=474, Percent_Identity=52.7426160337553, Blast_Score=473, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 52865; Mature: 52734

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSIAPVILCGGSGTRLWPLSRETYPKQFVDLGEGRTLFKDTLLRAQRTPESLEPVIVCN
CCCCCEEEEECCCCCEEEECCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEC
EAHRFYVTAALYECDVRATILLEPAPRNTAPAIALAALTLARDEADPLMLVLPSDHAIGN
CCCEEEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCC
EAAFFKGVESAAALAEQGHIVTFGITPASPETGFGYIEQGETLGYGGFRVARFVEKPDTA
CHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCCEECCCCCEEHHHHCCCCHH
AAQSMLDQGGFLWNSGMFLLRASVYLKELERFAPEIHAACCTAWQRRAADGAFCRPDADA
HHHHHHHCCCEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
FLASPSDSIDYAVMEQTDRAAVVPLSTGWSDLGSWEAFYQAEAGDDSGNVCHGDIMTQDA
EEECCCCCCCEEEEECCCCEEEEEECCCCCCCCCCHHEEEECCCCCCCCEEECCCCCCCC
ENCYFNAQHRLVTAIGVRDLVVVETRDAVLVAPRERVQEVKTMVGRLQSARRTECRQHPL
CCCEECCCCEEEEEECCCEEEEEEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCE
VYRPWGSYETLVMDGRFQVKRIIVNPGAELSLQMHHHRAEHWVVVSGTAEVTNGNETRLY
EEECCCCEEEEEECCCEEEEEEEECCCCCEEEEEEECCCCEEEEEECCEEECCCCCEEEE
TENQSTYIPVGTRHRLKNPGVIPLVLIEIQSGAYLGEDDIVRFADVYGREDLPAHGNENR
ECCCCEEEECCCHHHCCCCCEEEEEEEEEECCCEECCCHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PSIAPVILCGGSGTRLWPLSRETYPKQFVDLGEGRTLFKDTLLRAQRTPESLEPVIVCN
CCCCEEEEECCCCCEEEECCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEC
EAHRFYVTAALYECDVRATILLEPAPRNTAPAIALAALTLARDEADPLMLVLPSDHAIGN
CCCEEEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCC
EAAFFKGVESAAALAEQGHIVTFGITPASPETGFGYIEQGETLGYGGFRVARFVEKPDTA
CHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCCEECCCCCEEHHHHCCCCHH
AAQSMLDQGGFLWNSGMFLLRASVYLKELERFAPEIHAACCTAWQRRAADGAFCRPDADA
HHHHHHHCCCEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
FLASPSDSIDYAVMEQTDRAAVVPLSTGWSDLGSWEAFYQAEAGDDSGNVCHGDIMTQDA
EEECCCCCCCEEEEECCCCEEEEEECCCCCCCCCCHHEEEECCCCCCCCEEECCCCCCCC
ENCYFNAQHRLVTAIGVRDLVVVETRDAVLVAPRERVQEVKTMVGRLQSARRTECRQHPL
CCCEECCCCEEEEEECCCEEEEEEECCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCE
VYRPWGSYETLVMDGRFQVKRIIVNPGAELSLQMHHHRAEHWVVVSGTAEVTNGNETRLY
EEECCCCEEEEEECCCEEEEEEEECCCCCEEEEEEECCCCEEEEEECCEEECCCCCEEEE
TENQSTYIPVGTRHRLKNPGVIPLVLIEIQSGAYLGEDDIVRFADVYGREDLPAHGNENR
ECCCCEEEECCCHHHCCCCCEEEEEEEEEECCCEECCCHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]