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The map label for this gene is dksA [H]

Identifier: 220903574

GI number: 220903574

Start: 351112

End: 351474

Strand: Direct

Name: dksA [H]

Synonym: Ddes_0293

Alternate gene names: 220903574

Gene position: 351112-351474 (Clockwise)

Preceding gene: 220903573

Following gene: 220903575

Centisome position: 12.22

GC content: 53.72

Gene sequence:

>363_bases
ATGGATCACAAGGATTTGGAATATTTCCGTAAACTTCTTTCAGGTATGCTTGAAGAAGCCCAGCAAAAGGGCGACAGCAC
CATTGAAGAGCTGACTGACAGTAACGAAGTGTTCGCTGACCCTGCCGACAGGGCCACTGCCGAATCCGATCGCGCTTTTA
CCCTGCGTATTCGTGACCGGGAGCGACGGCTTATCCGCAAGATTCAGGCCGCATTGACCCGTATAGATGATGGAACCTAT
GGCATCTGCGAGGATTGCGGCGATGATATCAGCATTCCGCGCCTCAAGGCCCGCCCTGTGACCAGGCTTTGCATCAACTG
CAAGGCCAAGCAGGAAGAAGACGAACACCTCAGGGGAGACTAG

Upstream 100 bases:

>100_bases
GTTGGGAGACGTCTTTACAAAGACTTCGCTTGAAGATATAGGGGTCCATTGCGTTAATAGTTTGTGTTTGCGCCCCCAGC
GGCGTCCGCCGGAGGATTAC

Downstream 100 bases:

>100_bases
GCACCCCGGGCGCAGGCCCGCCGCCCCCGTATCCGGTTTGTCCGGCGCCCTTCGGGGCGCCTCTCGCGGGGGTGCCGCCG
CATGCGGCCTGCCGGTAACA

Product: TraR/DksA family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MDHKDLEYFRKLLSGMLEEAQQKGDSTIEELTDSNEVFADPADRATAESDRAFTLRIRDRERRLIRKIQAALTRIDDGTY
GICEDCGDDISIPRLKARPVTRLCINCKAKQEEDEHLRGD

Sequences:

>Translated_120_residues
MDHKDLEYFRKLLSGMLEEAQQKGDSTIEELTDSNEVFADPADRATAESDRAFTLRIRDRERRLIRKIQAALTRIDDGTY
GICEDCGDDISIPRLKARPVTRLCINCKAKQEEDEHLRGD
>Mature_120_residues
MDHKDLEYFRKLLSGMLEEAQQKGDSTIEELTDSNEVFADPADRATAESDRAFTLRIRDRERRLIRKIQAALTRIDDGTY
GICEDCGDDISIPRLKARPVTRLCINCKAKQEEDEHLRGD

Specific function: Dosage-Dependent Suppressor Of A Dnak Deletion Mutation. It Suppressed Not Only The Temperature-Sensitive Growth But Also The Filamentous Phenotype Of The Dnak Deletion Strain, While The Defect Of Lambda Growth Is Not Suppressed. [C]

COG id: COG1734

COG function: function code T; DnaK suppressor protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 dksA C4-type zinc finger [H]

Homologues:

Organism=Escherichia coli, GI1786338, Length=108, Percent_Identity=41.6666666666667, Blast_Score=95, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012784
- InterPro:   IPR000962
- InterPro:   IPR020458 [H]

Pfam domain/function: PF01258 zf-dskA_traR [H]

EC number: NA

Molecular weight: Translated: 13785; Mature: 13785

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS01102 ZF_DKSA_1 ; PS51128 ZF_DKSA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHKDLEYFRKLLSGMLEEAQQKGDSTIEELTDSNEVFADPADRATAESDRAFTLRIRDR
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECHH
ERRLIRKIQAALTRIDDGTYGICEDCGDDISIPRLKARPVTRLCINCKAKQEEDEHLRGD
HHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDHKDLEYFRKLLSGMLEEAQQKGDSTIEELTDSNEVFADPADRATAESDRAFTLRIRDR
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECHH
ERRLIRKIQAALTRIDDGTYGICEDCGDDISIPRLKARPVTRLCINCKAKQEEDEHLRGD
HHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 8063112 [H]