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The map label for this gene is tsr [C]

Identifier: 220903566

GI number: 220903566

Start: 338817

End: 340970

Strand: Reverse

Name: tsr [C]

Synonym: Ddes_0285

Alternate gene names: 220903566

Gene position: 340970-338817 (Counterclockwise)

Preceding gene: 220903567

Following gene: 220903565

Centisome position: 11.87

GC content: 58.96

Gene sequence:

>2154_bases
ATGAATATGTCAGTCCGCTACAAGGCGTTACTGCTGATCGGTGTTACCATCATAATTGCGCTGATCAGCTATGCCATCCT
GCTGCGTAACATGAATGATATGGAAGAACGCTACAGCGACAAGACACGCCTTGCTGTGGAACGGCTCATCGCCACAGAAG
CTGAAAAAATCAATACCTATATGACTGTCACACAGGACGGCGCGGCGGGTATTGCCATTGCCGGCGAGGCCCTGTGGATG
GTGCGGGGGCAGGATACGGCCGGGGCCGCCCAGGCCGTCAAGGATTACCTCAAGCTCAATATTGCCCGGTACCCCAAGGC
CGTGGGGTGCGGCATGTGGTACGAGCCCTACGTTTTTTCTCCCGGTGAAGCCTACTTCGGCTCCTATGCCCGTTGGGAAA
ACGGCAAAGTGGCCCTGACCATGGAATATAACGAAGCTGACTACGACTACCACAAACAGGACTGGTACACCCAGGCCATC
CCTGCCCAGTGGGACCGCAACAAACAACGCCCCGACCGGGTATACTGGTCAGCCCCGTATCTGGATGAGGCCTCAAACAC
GCTCATGATCACCGTGGGCGGCGTCATGTACAGCCCGCACGGGCGTATCATCGGCATGTCCACCCTGGACGTAAGCATTG
AAGACCTGCGCAAGACCGTAGGCAGCATAAAAATCACTCCGGCGTCCACCGCCTTCGCCGTAGACATGCGCAGCGGCCTG
ATCGCCGCCTACCCCGCCGACAACGCCTTGCTGCTCAAGCCAATGGAAAAGCTGCCCTTCAGTGATGCTCAAAAACTGCT
GGGTTCTGTGCCGCCCAACGGGCAAATCCGTTTTGCCGCAAGCATCAACGGGCAACCAAACACGATTTTTTACAGTGTTT
CCCCTACAGGTATGGGGCTTGGCATTGCCATTCCCGATGCGGAACTTTACGCCGAAGTGCACGCACTGGCGGCGTTCAAC
CGCAACACCGCTCTGGGCGCGGCAGGGGCCTTGCTGATATTTTTTGTCATCATTGGCCTTGCGTTGAACAGGATCATCAT
CAACCCCATCCTGTCCCTGTCGGCCTTTTCACGCTCGGTGGCCGAGGGCAGGCTTGATACACCCGTGGCCGAAAACTATA
AAAGTGAATTCGCCGTGCTGCGCAACGCCATGGTCGCCATGCTGGATACCCTGAAAAACAAGATGCAGGAGGCGGAACGC
CGCACTGAAGAGGCACGCGTCAACGCCCAGAATGCCGAAGCCTCACGCCACGCGGCGGAAGAAGCCACCGCACAGGCGCA
AAAAGCCCGCAGCGAAGGCATGCGGCAAGCCGCGGGCAGCCTGCGCACCGTGGTGGCCGTGACGGAAAGCGCCTCCGCGG
AGCTTGCGCAAAAAATCAATGCCTCCAGCCAGCGGGCTGAAAGCCAGTCCCGCCGCGTGGCAGAAACAGCTACCGCCATG
GAACAGCTGAGTGCCGCCGTACTGGAAATCTCGCATAATTCTGGTACGGCAGCCAACCTTTCAGAAGAATCCCGCGCGGC
AGCCGAACAGGGTACGGAACGGGTCTACCGTGTTCTGCGTGACGTAACCACGGTGCATCGCGACTTTCAGTCCGCCTACG
GCTCCGTTGACGACCTGAGCGGCAAGGCCAATGCCATCGGAACCATCGCCCGCACCATTGAAGACATTGCGGACCAGACC
AACCTGCTTGCCCTCAATGCCGCCATTGAAGCCGCCCGCGCCGGAGACGCCGGACGCGGCTTTGCTGTGGTAGCCGACGA
AGTGCGCAAACTGGCAGAAAAAACCATGACGGCCACCAAGGAAGTGGGGCAGTCCATCACAGACATCCAGCAGGCTGCCG
GAAGCACCCTGGTCAGCATGGACAATACAAAAAATCTTCTGGGTCAGGCCATGCAGGATGTGCAGGGGGCAGAAGACATA
TTGCGCCGCATCTCGGCCCTGATTATGGATTCCACCGACCAGATCCGCGCCATCGCCACAGCTGCCGAGCAGCAGTCTGC
CGCCACGGAAGAGGTCAATGCCTCCATCGTGGACATCAACCGCATTTCTGAAGAAACAGCGACTGCCATGCAGGAGGCCG
CCGCCGCTGTGGACGAACTGGGCAGACAGACCGCCGCGCTCCACAACCTGACCGACCAGCTGGAACGGAGTTAA

Upstream 100 bases:

>100_bases
ATAGTACTGATGGCAATAGCAACTACACAACACATCCATAACAGACAGGACACATTGCAAAAATAAAAGCAATAATCATT
ACCATTGCAGGAGTGTTCCC

Downstream 100 bases:

>100_bases
AGAATCGTAGCGGAGATCGTCCTGTGCAGGGGCTGTTTCTAAACCGGATTTGTGCCACAGGCAGAAAAATTTTTTGGTCT
GGCCGCTGGCAACATGTTTT

Product: Cache sensor-containing methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 717; Mature: 717

Protein sequence:

>717_residues
MNMSVRYKALLLIGVTIIIALISYAILLRNMNDMEERYSDKTRLAVERLIATEAEKINTYMTVTQDGAAGIAIAGEALWM
VRGQDTAGAAQAVKDYLKLNIARYPKAVGCGMWYEPYVFSPGEAYFGSYARWENGKVALTMEYNEADYDYHKQDWYTQAI
PAQWDRNKQRPDRVYWSAPYLDEASNTLMITVGGVMYSPHGRIIGMSTLDVSIEDLRKTVGSIKITPASTAFAVDMRSGL
IAAYPADNALLLKPMEKLPFSDAQKLLGSVPPNGQIRFAASINGQPNTIFYSVSPTGMGLGIAIPDAELYAEVHALAAFN
RNTALGAAGALLIFFVIIGLALNRIIINPILSLSAFSRSVAEGRLDTPVAENYKSEFAVLRNAMVAMLDTLKNKMQEAER
RTEEARVNAQNAEASRHAAEEATAQAQKARSEGMRQAAGSLRTVVAVTESASAELAQKINASSQRAESQSRRVAETATAM
EQLSAAVLEISHNSGTAANLSEESRAAAEQGTERVYRVLRDVTTVHRDFQSAYGSVDDLSGKANAIGTIARTIEDIADQT
NLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTMTATKEVGQSITDIQQAAGSTLVSMDNTKNLLGQAMQDVQGAEDI
LRRISALIMDSTDQIRAIATAAEQQSAATEEVNASIVDINRISEETATAMQEAAAAVDELGRQTAALHNLTDQLERS

Sequences:

>Translated_717_residues
MNMSVRYKALLLIGVTIIIALISYAILLRNMNDMEERYSDKTRLAVERLIATEAEKINTYMTVTQDGAAGIAIAGEALWM
VRGQDTAGAAQAVKDYLKLNIARYPKAVGCGMWYEPYVFSPGEAYFGSYARWENGKVALTMEYNEADYDYHKQDWYTQAI
PAQWDRNKQRPDRVYWSAPYLDEASNTLMITVGGVMYSPHGRIIGMSTLDVSIEDLRKTVGSIKITPASTAFAVDMRSGL
IAAYPADNALLLKPMEKLPFSDAQKLLGSVPPNGQIRFAASINGQPNTIFYSVSPTGMGLGIAIPDAELYAEVHALAAFN
RNTALGAAGALLIFFVIIGLALNRIIINPILSLSAFSRSVAEGRLDTPVAENYKSEFAVLRNAMVAMLDTLKNKMQEAER
RTEEARVNAQNAEASRHAAEEATAQAQKARSEGMRQAAGSLRTVVAVTESASAELAQKINASSQRAESQSRRVAETATAM
EQLSAAVLEISHNSGTAANLSEESRAAAEQGTERVYRVLRDVTTVHRDFQSAYGSVDDLSGKANAIGTIARTIEDIADQT
NLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTMTATKEVGQSITDIQQAAGSTLVSMDNTKNLLGQAMQDVQGAEDI
LRRISALIMDSTDQIRAIATAAEQQSAATEEVNASIVDINRISEETATAMQEAAAAVDELGRQTAALHNLTDQLERS
>Mature_717_residues
MNMSVRYKALLLIGVTIIIALISYAILLRNMNDMEERYSDKTRLAVERLIATEAEKINTYMTVTQDGAAGIAIAGEALWM
VRGQDTAGAAQAVKDYLKLNIARYPKAVGCGMWYEPYVFSPGEAYFGSYARWENGKVALTMEYNEADYDYHKQDWYTQAI
PAQWDRNKQRPDRVYWSAPYLDEASNTLMITVGGVMYSPHGRIIGMSTLDVSIEDLRKTVGSIKITPASTAFAVDMRSGL
IAAYPADNALLLKPMEKLPFSDAQKLLGSVPPNGQIRFAASINGQPNTIFYSVSPTGMGLGIAIPDAELYAEVHALAAFN
RNTALGAAGALLIFFVIIGLALNRIIINPILSLSAFSRSVAEGRLDTPVAENYKSEFAVLRNAMVAMLDTLKNKMQEAER
RTEEARVNAQNAEASRHAAEEATAQAQKARSEGMRQAAGSLRTVVAVTESASAELAQKINASSQRAESQSRRVAETATAM
EQLSAAVLEISHNSGTAANLSEESRAAAEQGTERVYRVLRDVTTVHRDFQSAYGSVDDLSGKANAIGTIARTIEDIADQT
NLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTMTATKEVGQSITDIQQAAGSTLVSMDNTKNLLGQAMQDVQGAEDI
LRRISALIMDSTDQIRAIATAAEQQSAATEEVNASIVDINRISEETATAMQEAAAAVDELGRQTAALHNLTDQLERS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=264, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1788194, Length=364, Percent_Identity=29.3956043956044, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1787690, Length=250, Percent_Identity=32.8, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788195, Length=226, Percent_Identity=34.5132743362832, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1789453, Length=250, Percent_Identity=29.6, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 77491; Mature: 77491

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMSVRYKALLLIGVTIIIALISYAILLRNMNDMEERYSDKTRLAVERLIATEAEKINTY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHCCEE
MTVTQDGAAGIAIAGEALWMVRGQDTAGAAQAVKDYLKLNIARYPKAVGCGMWYEPYVFS
EEEECCCCCCEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEEEC
PGEAYFGSYARWENGKVALTMEYNEADYDYHKQDWYTQAIPAQWDRNKQRPDRVYWSAPY
CCHHHHCCCCEECCCCEEEEEECCCCCCCCCHHCCHHHCCCCHHCCCCCCCCCEEECCCC
LDEASNTLMITVGGVMYSPHGRIIGMSTLDVSIEDLRKTVGSIKITPASTAFAVDMRSGL
CCCCCCEEEEEECCEEECCCCCEEEEEECCCCHHHHHHHHCCEEECCCCCEEEEECCCCE
IAAYPADNALLLKPMEKLPFSDAQKLLGSVPPNGQIRFAASINGQPNTIFYSVSPTGMGL
EEEECCCCCEEECCHHHCCCHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCCCCEE
GIAIPDAELYAEVHALAAFNRNTALGAAGALLIFFVIIGLALNRIIINPILSLSAFSRSV
EEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEGRLDTPVAENYKSEFAVLRNAMVAMLDTLKNKMQEAERRTEEARVNAQNAEASRHAAE
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
EATAQAQKARSEGMRQAAGSLRTVVAVTESASAELAQKINASSQRAESQSRRVAETATAM
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
EQLSAAVLEISHNSGTAANLSEESRAAAEQGTERVYRVLRDVTTVHRDFQSAYGSVDDLS
HHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCC
GKANAIGTIARTIEDIADQTNLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTMTATK
CCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
EVGQSITDIQQAAGSTLVSMDNTKNLLGQAMQDVQGAEDILRRISALIMDSTDQIRAIAT
HHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHH
AAEQQSAATEEVNASIVDINRISEETATAMQEAAAAVDELGRQTAALHNLTDQLERS
HHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNMSVRYKALLLIGVTIIIALISYAILLRNMNDMEERYSDKTRLAVERLIATEAEKINTY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHCCEE
MTVTQDGAAGIAIAGEALWMVRGQDTAGAAQAVKDYLKLNIARYPKAVGCGMWYEPYVFS
EEEECCCCCCEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCCCEEEC
PGEAYFGSYARWENGKVALTMEYNEADYDYHKQDWYTQAIPAQWDRNKQRPDRVYWSAPY
CCHHHHCCCCEECCCCEEEEEECCCCCCCCCHHCCHHHCCCCHHCCCCCCCCCEEECCCC
LDEASNTLMITVGGVMYSPHGRIIGMSTLDVSIEDLRKTVGSIKITPASTAFAVDMRSGL
CCCCCCEEEEEECCEEECCCCCEEEEEECCCCHHHHHHHHCCEEECCCCCEEEEECCCCE
IAAYPADNALLLKPMEKLPFSDAQKLLGSVPPNGQIRFAASINGQPNTIFYSVSPTGMGL
EEEECCCCCEEECCHHHCCCHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCCCCEE
GIAIPDAELYAEVHALAAFNRNTALGAAGALLIFFVIIGLALNRIIINPILSLSAFSRSV
EEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEGRLDTPVAENYKSEFAVLRNAMVAMLDTLKNKMQEAERRTEEARVNAQNAEASRHAAE
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
EATAQAQKARSEGMRQAAGSLRTVVAVTESASAELAQKINASSQRAESQSRRVAETATAM
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
EQLSAAVLEISHNSGTAANLSEESRAAAEQGTERVYRVLRDVTTVHRDFQSAYGSVDDLS
HHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCC
GKANAIGTIARTIEDIADQTNLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTMTATK
CCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
EVGQSITDIQQAAGSTLVSMDNTKNLLGQAMQDVQGAEDILRRISALIMDSTDQIRAIAT
HHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHH
AAEQQSAATEEVNASIVDINRISEETATAMQEAAAAVDELGRQTAALHNLTDQLERS
HHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA