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The map label for this gene is yicO [C]

Identifier: 220903562

GI number: 220903562

Start: 333003

End: 334313

Strand: Direct

Name: yicO [C]

Synonym: Ddes_0281

Alternate gene names: 220903562

Gene position: 333003-334313 (Clockwise)

Preceding gene: 220903561

Following gene: 220903563

Centisome position: 11.59

GC content: 57.44

Gene sequence:

>1311_bases
ATGAGTGTGCTGGAAAAACTGTTTAATCCCGCTGCAAGGGGCAGCACGGTCAAAAGGGAAATGCTGGCAGGACTCACCAG
CTTCATGGCCATGTGCTACCTTATTTTTGTGGTTCCCGGCATGCTGGCTGACGCGGGCATGCCCAAAGATTCCGCCGTGG
CTTCCACCATATGGGTGACCATTATCGCCACCCTGGTTATGGGCCTGTGGGCCAGATTTCCTGTGGGGGTGGCTCCGGGA
CTCGGTATCACGGCATTTTTCGCCTACTATGTGTGTGGCCCGGCCGGATATTCCTGGCAGACGGGGCTGGGAGCCGTGTT
TATTTCCGGTGTGGTTTTTCTGCTGCTCACGGTCACACGCATACGCCAGCTCATCATCAATGCCGTGCCTATGGATCTCA
AATACGCCATTGTGGTGGGTATCGGGGCTTTTATCGCCTTTATCGGCATGAAAAGCTGCGGCATTGTGGCGGCTGACCCC
GCCACCTTTGTGACGCTGGGCAATCTGGGCAATCCCGGAACCCTGCTTTCCATTGTGGGCATCTTTCTTATTGGCGGCCT
GCTGGCCCTGCGCGTGCGCGGAGCCATGATCATAGGCATTCTGGTCATCACGGTGGCCGGCATAGCCCTTGGCGTGTCGC
CCCTGCCCAAAGGGCCCATATTTTCTACCAGCCTGCCCATGCCCACTGAAACCTTCATGCAGATGGACATCAAGGGTGCG
CTGCATCACGGGCTTATTTCCATTATCTTTACCCTGACGATGGTGGACCTTTTCGACAATATGGGCGTACTCATCGGGCT
TTCGCAGAAGGCCGGGTTCATCCGCGAAGACGGCCATATCGAAAACCTCGACAAGGCCCTTATTACCGACTCTATGGCTA
CCATGGCCAGCGCCGTCATGGGCGCTACCACGGCCACGAGCTACCTCGAAAGCGCCGCCGGTGTTGCAGAGGGTGGCCGC
ACGGGGCTTACCGCCGTGACCATTGCCGTACTGTTTTTTCTGGCGCTCTTTTTCTCGCCTCTGGTGGGCATGGTTCCCGC
CTACGCCACCGCGCCGGTGCTTATCATCGTGGGTGCCATGATGATGCAGGAAGTGGGGCGTATCTGCTTCAAGGACTTTA
CCGTGGCGCTGCCCGCGTTTTTGACCATCATCAGCATGCCGCTGACCTTCAACATTGCTACCGGCTTTGGTTTCGGCTTT
GTGAGCTGGGTGGGCATCAAGGCCCTGGCCGGACGCTTCAAGGACCTGAACCTGGTCATGCTCTGCATTGCGCTGTGCTT
CATCATCAACTTTGCCTTGCGCTTGCCGTAG

Upstream 100 bases:

>100_bases
GCGCCGGGTATATCGGATATGTTTTGCATTTTTGCTTTGCGGGCAGGGAAGGTCTGGGCTTCCATGCTCCGGTCGGCGTC
GCACATAAGGAGGAAACGCC

Downstream 100 bases:

>100_bases
GGACCAGTTCCCGGAACTGCCGGCAGTATTGCCCCGGCGCCTGTGACACAGGCGCCGGGGCTGTTTGTTTGTCCGCCTGT
CTGGCCTGCTTTATGAGCGT

Product: Xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MSVLEKLFNPAARGSTVKREMLAGLTSFMAMCYLIFVVPGMLADAGMPKDSAVASTIWVTIIATLVMGLWARFPVGVAPG
LGITAFFAYYVCGPAGYSWQTGLGAVFISGVVFLLLTVTRIRQLIINAVPMDLKYAIVVGIGAFIAFIGMKSCGIVAADP
ATFVTLGNLGNPGTLLSIVGIFLIGGLLALRVRGAMIIGILVITVAGIALGVSPLPKGPIFSTSLPMPTETFMQMDIKGA
LHHGLISIIFTLTMVDLFDNMGVLIGLSQKAGFIREDGHIENLDKALITDSMATMASAVMGATTATSYLESAAGVAEGGR
TGLTAVTIAVLFFLALFFSPLVGMVPAYATAPVLIIVGAMMMQEVGRICFKDFTVALPAFLTIISMPLTFNIATGFGFGF
VSWVGIKALAGRFKDLNLVMLCIALCFIINFALRLP

Sequences:

>Translated_436_residues
MSVLEKLFNPAARGSTVKREMLAGLTSFMAMCYLIFVVPGMLADAGMPKDSAVASTIWVTIIATLVMGLWARFPVGVAPG
LGITAFFAYYVCGPAGYSWQTGLGAVFISGVVFLLLTVTRIRQLIINAVPMDLKYAIVVGIGAFIAFIGMKSCGIVAADP
ATFVTLGNLGNPGTLLSIVGIFLIGGLLALRVRGAMIIGILVITVAGIALGVSPLPKGPIFSTSLPMPTETFMQMDIKGA
LHHGLISIIFTLTMVDLFDNMGVLIGLSQKAGFIREDGHIENLDKALITDSMATMASAVMGATTATSYLESAAGVAEGGR
TGLTAVTIAVLFFLALFFSPLVGMVPAYATAPVLIIVGAMMMQEVGRICFKDFTVALPAFLTIISMPLTFNIATGFGFGF
VSWVGIKALAGRFKDLNLVMLCIALCFIINFALRLP
>Mature_435_residues
SVLEKLFNPAARGSTVKREMLAGLTSFMAMCYLIFVVPGMLADAGMPKDSAVASTIWVTIIATLVMGLWARFPVGVAPGL
GITAFFAYYVCGPAGYSWQTGLGAVFISGVVFLLLTVTRIRQLIINAVPMDLKYAIVVGIGAFIAFIGMKSCGIVAADPA
TFVTLGNLGNPGTLLSIVGIFLIGGLLALRVRGAMIIGILVITVAGIALGVSPLPKGPIFSTSLPMPTETFMQMDIKGAL
HHGLISIIFTLTMVDLFDNMGVLIGLSQKAGFIREDGHIENLDKALITDSMATMASAVMGATTATSYLESAAGVAEGGRT
GLTAVTIAVLFFLALFFSPLVGMVPAYATAPVLIIVGAMMMQEVGRICFKDFTVALPAFLTIISMPLTFNIATGFGFGFV
SWVGIKALAGRFKDLNLVMLCIALCFIINFALRLP

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=430, Percent_Identity=40.9302325581395, Blast_Score=328, Evalue=5e-91,
Organism=Escherichia coli, GI1790150, Length=427, Percent_Identity=38.6416861826698, Blast_Score=304, Evalue=9e-84,
Organism=Escherichia coli, GI1790499, Length=438, Percent_Identity=36.986301369863, Blast_Score=254, Evalue=7e-69,
Organism=Escherichia coli, GI48994909, Length=424, Percent_Identity=36.5566037735849, Blast_Score=236, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45856; Mature: 45725

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLEKLFNPAARGSTVKREMLAGLTSFMAMCYLIFVVPGMLADAGMPKDSAVASTIWVT
CCHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IIATLVMGLWARFPVGVAPGLGITAFFAYYVCGPAGYSWQTGLGAVFISGVVFLLLTVTR
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IRQLIINAVPMDLKYAIVVGIGAFIAFIGMKSCGIVAADPATFVTLGNLGNPGTLLSIVG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEECCCCCCHHHHHHHH
IFLIGGLLALRVRGAMIIGILVITVAGIALGVSPLPKGPIFSTSLPMPTETFMQMDIKGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LHHGLISIIFTLTMVDLFDNMGVLIGLSQKAGFIREDGHIENLDKALITDSMATMASAVM
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GATTATSYLESAAGVAEGGRTGLTAVTIAVLFFLALFFSPLVGMVPAYATAPVLIIVGAM
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMQEVGRICFKDFTVALPAFLTIISMPLTFNIATGFGFGFVSWVGIKALAGRFKDLNLVM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHCCHHHHHHHHHHHHHHHCCCHHHHH
LCIALCFIINFALRLP
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVLEKLFNPAARGSTVKREMLAGLTSFMAMCYLIFVVPGMLADAGMPKDSAVASTIWVT
CHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IIATLVMGLWARFPVGVAPGLGITAFFAYYVCGPAGYSWQTGLGAVFISGVVFLLLTVTR
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IRQLIINAVPMDLKYAIVVGIGAFIAFIGMKSCGIVAADPATFVTLGNLGNPGTLLSIVG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEECCCCCCHHHHHHHH
IFLIGGLLALRVRGAMIIGILVITVAGIALGVSPLPKGPIFSTSLPMPTETFMQMDIKGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
LHHGLISIIFTLTMVDLFDNMGVLIGLSQKAGFIREDGHIENLDKALITDSMATMASAVM
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GATTATSYLESAAGVAEGGRTGLTAVTIAVLFFLALFFSPLVGMVPAYATAPVLIIVGAM
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMQEVGRICFKDFTVALPAFLTIISMPLTFNIATGFGFGFVSWVGIKALAGRFKDLNLVM
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHCCHHHHHHHHHHHHHHHCCCHHHHH
LCIALCFIINFALRLP
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]