Click here to switch to the map view.

The map label for this gene is cidA [H]

Identifier: 220903493

GI number: 220903493

Start: 262112

End: 262501

Strand: Direct

Name: cidA [H]

Synonym: Ddes_0211

Alternate gene names: 220903493

Gene position: 262112-262501 (Clockwise)

Preceding gene: 220903491

Following gene: 220903494

Centisome position: 9.12

GC content: 51.03

Gene sequence:

>390_bases
ATGAAAGAGACATGGAAGTTTTTGTGGCAGATGGCCTTTCTTATGGCCCTCTTTTTGGCGTCAAACTGGCTGGTGGGCGT
TACTGGTCTGCCCATGCCGGGAAACGTGCTTGGCATTATTGTGCTTTTTCTTCTTTTGCTCACAGGTGTTGTTAAAGAAG
ACCACATCAGCACGGCAGCCAATTTTTTGCTCAAGCATATGGTTTTTTTCTTTGTGCCTGTGGCTGTGGGCCTGATGCAG
TGGGGCGGCGTTTTTTATGATTACGGCTGGATTTTGCTGGCAGCCATTGTTGTGGGGGCCATTTTACCCCTGCTGACAGT
GGGGCTTCTGGGCAGGGCTTTGCGCCGTCGCACGCGCCGGAAGGAGGAAGAATCATGCAGTCCTATGTAA

Upstream 100 bases:

>100_bases
TTATTCAGTTGTCATGAACATCTTTACCATTATATAGTCCCCTGCAAATGGCAAGCACCGAAATTGTTCGCGCGGCGGCC
CAAATGTGGTGGTAGCGGTA

Downstream 100 bases:

>100_bases
GCATAAGCACGGTTCTTTGCATTCTGGGCACGTTGCTGGCCTACATGGCGGTGCGCGCCCTGTACATGCGCTACAGGCAT
CCGTTGATCAATATTGTGGC

Product: LrgA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MKETWKFLWQMAFLMALFLASNWLVGVTGLPMPGNVLGIIVLFLLLLTGVVKEDHISTAANFLLKHMVFFFVPVAVGLMQ
WGGVFYDYGWILLAAIVVGAILPLLTVGLLGRALRRRTRRKEEESCSPM

Sequences:

>Translated_129_residues
MKETWKFLWQMAFLMALFLASNWLVGVTGLPMPGNVLGIIVLFLLLLTGVVKEDHISTAANFLLKHMVFFFVPVAVGLMQ
WGGVFYDYGWILLAAIVVGAILPLLTVGLLGRALRRRTRRKEEESCSPM
>Mature_129_residues
MKETWKFLWQMAFLMALFLASNWLVGVTGLPMPGNVLGIIVLFLLLLTGVVKEDHISTAANFLLKHMVFFFVPVAVGLMQ
WGGVFYDYGWILLAAIVVGAILPLLTVGLLGRALRRRTRRKEEESCSPM

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 14454; Mature: 14454

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKETWKFLWQMAFLMALFLASNWLVGVTGLPMPGNVLGIIVLFLLLLTGVVKEDHISTAA
CCHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NFLLKHMVFFFVPVAVGLMQWGGVFYDYGWILLAAIVVGAILPLLTVGLLGRALRRRTRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEEESCSPM
HHHHCCCCC
>Mature Secondary Structure
MKETWKFLWQMAFLMALFLASNWLVGVTGLPMPGNVLGIIVLFLLLLTGVVKEDHISTAA
CCHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NFLLKHMVFFFVPVAVGLMQWGGVFYDYGWILLAAIVVGAILPLLTVGLLGRALRRRTRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEEESCSPM
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA