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The map label for this gene is cutA [H]

Identifier: 220903481

GI number: 220903481

Start: 250642

End: 250965

Strand: Direct

Name: cutA [H]

Synonym: Ddes_0199

Alternate gene names: 220903481

Gene position: 250642-250965 (Clockwise)

Preceding gene: 220903476

Following gene: 220903482

Centisome position: 8.72

GC content: 62.04

Gene sequence:

>324_bases
ATGTCCTATCTGGTTTATGTCACCGCGCCCGATGAAGAGCTTGCCCTTGATCTTGCCCGCATGCTGGTAGAGCAAAGCCT
TGCCGCCGGGGTGAACATCGTGCCTGGCGCGCGTTCCATTTATCGCTGGCGCGGCCAGGTGCATGATGCCGCGGAATGCC
TGCTGATGGCCCAGGTAAGCCATGAGGCGCTGCCCGCCTTTGAGGCCGCCGTGAAAAGCATGCACAGCTACGAGGTTCCC
TGTATCGTGGCCCTGCCCATAGAGGCCGGGCATGAGCCGTATCTGCGCTGGATCAGGGAAAACAGCCGTCCGCCCTCGGC
CTGA

Upstream 100 bases:

>100_bases
GGCAGCCTGCAAGCCGTGGCGGGCGCGGTTCGCGGCCTCTTTGTTTTTTGCGGGTTTGGGTATAAGCTGCCTCGCAACGA
CATGCTGTAGGGGAGAAATC

Downstream 100 bases:

>100_bases
CATTGCCGCGCCGTGGAGATTCCGGCATGATTATCTGCCCTTGCGGCGTCCGGTGCGAACCGAAAATGCGCGGGCCTGCG
CCGGGGCGCAGCGGCAATTA

Product: CutA1 divalent ion tolerance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 107; Mature: 106

Protein sequence:

>107_residues
MSYLVYVTAPDEELALDLARMLVEQSLAAGVNIVPGARSIYRWRGQVHDAAECLLMAQVSHEALPAFEAAVKSMHSYEVP
CIVALPIEAGHEPYLRWIRENSRPPSA

Sequences:

>Translated_107_residues
MSYLVYVTAPDEELALDLARMLVEQSLAAGVNIVPGARSIYRWRGQVHDAAECLLMAQVSHEALPAFEAAVKSMHSYEVP
CIVALPIEAGHEPYLRWIRENSRPPSA
>Mature_106_residues
SYLVYVTAPDEELALDLARMLVEQSLAAGVNIVPGARSIYRWRGQVHDAAECLLMAQVSHEALPAFEAAVKSMHSYEVPC
IVALPIEAGHEPYLRWIRENSRPPSA

Specific function: Involved in resistance toward heavy metals [H]

COG id: COG1324

COG function: function code P; Uncharacterized protein involved in tolerance to divalent cations

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutA family [H]

Homologues:

Organism=Homo sapiens, GI62526024, Length=95, Percent_Identity=43.1578947368421, Blast_Score=98, Evalue=1e-21,
Organism=Homo sapiens, GI62526022, Length=95, Percent_Identity=43.1578947368421, Blast_Score=98, Evalue=1e-21,
Organism=Homo sapiens, GI7706244, Length=95, Percent_Identity=43.1578947368421, Blast_Score=98, Evalue=1e-21,
Organism=Homo sapiens, GI62198241, Length=95, Percent_Identity=43.1578947368421, Blast_Score=98, Evalue=2e-21,
Organism=Homo sapiens, GI62526026, Length=95, Percent_Identity=43.1578947368421, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790579, Length=104, Percent_Identity=37.5, Blast_Score=70, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32565476, Length=104, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641937, Length=100, Percent_Identity=40, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004323
- InterPro:   IPR011322 [H]

Pfam domain/function: PF03091 CutA1 [H]

EC number: NA

Molecular weight: Translated: 11846; Mature: 11715

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYLVYVTAPDEELALDLARMLVEQSLAAGVNIVPGARSIYRWRGQVHDAAECLLMAQVS
CCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
HEALPAFEAAVKSMHSYEVPCIVALPIEAGHEPYLRWIRENSRPPSA
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SYLVYVTAPDEELALDLARMLVEQSLAAGVNIVPGARSIYRWRGQVHDAAECLLMAQVS
CEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
HEALPAFEAAVKSMHSYEVPCIVALPIEAGHEPYLRWIRENSRPPSA
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA