Click here to switch to the map view.

The map label for this gene is yciR [C]

Identifier: 220903473

GI number: 220903473

Start: 238508

End: 239965

Strand: Direct

Name: yciR [C]

Synonym: Ddes_0189

Alternate gene names: 220903473

Gene position: 238508-239965 (Clockwise)

Preceding gene: 220903472

Following gene: 220903475

Centisome position: 8.3

GC content: 55.9

Gene sequence:

>1458_bases
ATGCATTTTCTGGGGGATGGAACGGAAGACCGCGCCGGGGGGTACATGCGGCTTTCCGGCGACTGGGGCGTGGAGTCCTT
TTTTCCCGAACTGGACCTCAAAAGTCGGGAAAGCTGCCGGATACGGCGCCTGCTGGGTTGTATGGAGCAGTATGACCGCA
CCACATGGCTTTTGCAGTTTGAATCTTTTTTGCAAGAAGCCCTGCGGGTTGTGCGTTCAGATCTGACGGGACGGCGATTT
GCTGTTCTGCATGCGGATATGCAGGGTTTTCAGGTGCTCAACCGTCTTTACGGCGAGCAGGCGGGCAACAGCATGTTGCG
CGCCTTTGCCGCATTTTTGCGGCACCTGGATTGCTATGTGTGCGCCAGCCGCATTTTTGCGGACCAGTTTACCATGCTTT
TTACGGTTCCCGAGGGAACGAGCCTTGAAGTCGCAGCCGGAAAGATTGTGGCCAAGGGCGAACTGTTTCTTGCAAAAAAG
CGCAATCTGCACCCACGCAGCCATCTGGCCTTTGTGGGAGGGGTCTGCCCTGTAGAAGGTACGCCCGCCAGCCTGCACCC
GCACGTAAGCCGGGCGGACCAGGCGCGGCGCGCGCTCAAGCCCACCCTGCGCTCCCGCGGGGGAATTTTTACCGATGCGA
TGGAAGTGCGCCGCCTGCAGCGGCAGAGCCTGTATGAAGACGTGATCAAGTCGCTGGAATGCGGCGGCGTTTTCTTTCTG
CTGCAACCGCAAATAGATATTGCCACCGGCGCAGTGGTGGGGGCCGAGGCCCTGGCAAGAATGCGCACTCCTGACGGCAG
GGATATCATGCCCGCCAGTTTTGTGCCTCTGCTTGAAGAGTCGGGCGACATCATCAGCCTGGATTTTCTCGTTTACGAGC
AGGTTTGCCGCTACCTGCGGCAATGTCTTGATACGGGCAGACCGTTTGTTCCCGTAACCGTCAATATTTCCCGCGAAAAT
TTTAAAAATCCTGCCTTTGCCGAAGAATTTCATGCCCTGGTCTGCGCGCACGGTCTTGAACCGCGGCATGTGGGACTGGA
GATAACTGAAAGCGTTTTTATCAAAAACCTTACAGAAATACGCGACAGCGTGCGCCAGTTCAAGCAGTATGGGTATTCCA
TCTGGCTTGACGATTTCGGCGCGGGCTATTCAAGCCTCAATGTGCTCAAGGAAGTGCCTTTCGATGTCATAAAGATTGAC
AGAAGTCTGCTTGGTTCCGGTGAAATAGCGTCGGTCAACAAAAGCATCATCAGCAGTATCATCAGTCTTTCCGGTGACCT
GCATATGGAAGTGTTGTGCGAAGGGGTGGAAAACGCCACGCAGCGCAATTTTCTTCTCGGTTTTGGCGGCATCCAGGCGC
AGGGATTTTTTTATGCCCGCCCCATGTCGTGTCAGGACTTTGAAGCACTCATGGAAGGCGGGGCCACGCTCAATCCTCCG
CAGGGCGGCGTACGCTGA

Upstream 100 bases:

>100_bases
CTTTACAAAATATTCAAATATACGCTAGTTTCGTTCTGTCCAGAATTGTAGGAAAATGCCGTTGTGGCGTCTTCTCGCCG
GGCCGTAGAAAGGGGGAGGC

Downstream 100 bases:

>100_bases
GGGCGCAGCCGCGGGCAGGCCATGCAAAAGAATATCCGCGCCGCAAGCGGCGCGGATGGCAAAAGACCGCCCAAGGGCTT
CTGTTTCAGGCGTGCCGCGC

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MHFLGDGTEDRAGGYMRLSGDWGVESFFPELDLKSRESCRIRRLLGCMEQYDRTTWLLQFESFLQEALRVVRSDLTGRRF
AVLHADMQGFQVLNRLYGEQAGNSMLRAFAAFLRHLDCYVCASRIFADQFTMLFTVPEGTSLEVAAGKIVAKGELFLAKK
RNLHPRSHLAFVGGVCPVEGTPASLHPHVSRADQARRALKPTLRSRGGIFTDAMEVRRLQRQSLYEDVIKSLECGGVFFL
LQPQIDIATGAVVGAEALARMRTPDGRDIMPASFVPLLEESGDIISLDFLVYEQVCRYLRQCLDTGRPFVPVTVNISREN
FKNPAFAEEFHALVCAHGLEPRHVGLEITESVFIKNLTEIRDSVRQFKQYGYSIWLDDFGAGYSSLNVLKEVPFDVIKID
RSLLGSGEIASVNKSIISSIISLSGDLHMEVLCEGVENATQRNFLLGFGGIQAQGFFYARPMSCQDFEALMEGGATLNPP
QGGVR

Sequences:

>Translated_485_residues
MHFLGDGTEDRAGGYMRLSGDWGVESFFPELDLKSRESCRIRRLLGCMEQYDRTTWLLQFESFLQEALRVVRSDLTGRRF
AVLHADMQGFQVLNRLYGEQAGNSMLRAFAAFLRHLDCYVCASRIFADQFTMLFTVPEGTSLEVAAGKIVAKGELFLAKK
RNLHPRSHLAFVGGVCPVEGTPASLHPHVSRADQARRALKPTLRSRGGIFTDAMEVRRLQRQSLYEDVIKSLECGGVFFL
LQPQIDIATGAVVGAEALARMRTPDGRDIMPASFVPLLEESGDIISLDFLVYEQVCRYLRQCLDTGRPFVPVTVNISREN
FKNPAFAEEFHALVCAHGLEPRHVGLEITESVFIKNLTEIRDSVRQFKQYGYSIWLDDFGAGYSSLNVLKEVPFDVIKID
RSLLGSGEIASVNKSIISSIISLSGDLHMEVLCEGVENATQRNFLLGFGGIQAQGFFYARPMSCQDFEALMEGGATLNPP
QGGVR
>Mature_485_residues
MHFLGDGTEDRAGGYMRLSGDWGVESFFPELDLKSRESCRIRRLLGCMEQYDRTTWLLQFESFLQEALRVVRSDLTGRRF
AVLHADMQGFQVLNRLYGEQAGNSMLRAFAAFLRHLDCYVCASRIFADQFTMLFTVPEGTSLEVAAGKIVAKGELFLAKK
RNLHPRSHLAFVGGVCPVEGTPASLHPHVSRADQARRALKPTLRSRGGIFTDAMEVRRLQRQSLYEDVIKSLECGGVFFL
LQPQIDIATGAVVGAEALARMRTPDGRDIMPASFVPLLEESGDIISLDFLVYEQVCRYLRQCLDTGRPFVPVTVNISREN
FKNPAFAEEFHALVCAHGLEPRHVGLEITESVFIKNLTEIRDSVRQFKQYGYSIWLDDFGAGYSSLNVLKEVPFDVIKID
RSLLGSGEIASVNKSIISSIISLSGDLHMEVLCEGVENATQRNFLLGFGGIQAQGFFYARPMSCQDFEALMEGGATLNPP
QGGVR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=394, Percent_Identity=29.6954314720812, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI226510982, Length=255, Percent_Identity=32.5490196078431, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI87081743, Length=261, Percent_Identity=30.2681992337165, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1790496, Length=256, Percent_Identity=32.421875, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87081921, Length=273, Percent_Identity=28.5714285714286, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787055, Length=258, Percent_Identity=29.0697674418605, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI87081845, Length=256, Percent_Identity=26.5625, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1786507, Length=236, Percent_Identity=29.2372881355932, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788502, Length=244, Percent_Identity=26.2295081967213, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI87081980, Length=241, Percent_Identity=29.045643153527, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788849, Length=242, Percent_Identity=29.3388429752066, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87082096, Length=213, Percent_Identity=28.6384976525822, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 54060; Mature: 54060

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFLGDGTEDRAGGYMRLSGDWGVESFFPELDLKSRESCRIRRLLGCMEQYDRTTWLLQF
CCCCCCCCCCCCCCEEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHH
ESFLQEALRVVRSDLTGRRFAVLHADMQGFQVLNRLYGEQAGNSMLRAFAAFLRHLDCYV
HHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
CASRIFADQFTMLFTVPEGTSLEVAAGKIVAKGELFLAKKRNLHPRSHLAFVGGVCPVEG
HHHHHHHHCEEEEEECCCCCEEEEECCEEEECCCEEEECCCCCCCHHHHHHHCCCCCCCC
TPASLHPHVSRADQARRALKPTLRSRGGIFTDAMEVRRLQRQSLYEDVIKSLECGGVFFL
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LQPQIDIATGAVVGAEALARMRTPDGRDIMPASFVPLLEESGDIISLDFLVYEQVCRYLR
ECCCCCHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHH
QCLDTGRPFVPVTVNISRENFKNPAFAEEFHALVCAHGLEPRHVGLEITESVFIKNLTEI
HHHHCCCCEEEEEEEECHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
RDSVRQFKQYGYSIWLDDFGAGYSSLNVLKEVPFDVIKIDRSLLGSGEIASVNKSIISSI
HHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
ISLSGDLHMEVLCEGVENATQRNFLLGFGGIQAQGFFYARPMSCQDFEALMEGGATLNPP
HHHCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEECCCCHHHHHHHHHCCCCCCCC
QGGVR
CCCCC
>Mature Secondary Structure
MHFLGDGTEDRAGGYMRLSGDWGVESFFPELDLKSRESCRIRRLLGCMEQYDRTTWLLQF
CCCCCCCCCCCCCCEEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHH
ESFLQEALRVVRSDLTGRRFAVLHADMQGFQVLNRLYGEQAGNSMLRAFAAFLRHLDCYV
HHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
CASRIFADQFTMLFTVPEGTSLEVAAGKIVAKGELFLAKKRNLHPRSHLAFVGGVCPVEG
HHHHHHHHCEEEEEECCCCCEEEEECCEEEECCCEEEECCCCCCCHHHHHHHCCCCCCCC
TPASLHPHVSRADQARRALKPTLRSRGGIFTDAMEVRRLQRQSLYEDVIKSLECGGVFFL
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
LQPQIDIATGAVVGAEALARMRTPDGRDIMPASFVPLLEESGDIISLDFLVYEQVCRYLR
ECCCCCHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHH
QCLDTGRPFVPVTVNISRENFKNPAFAEEFHALVCAHGLEPRHVGLEITESVFIKNLTEI
HHHHCCCCEEEEEEEECHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
RDSVRQFKQYGYSIWLDDFGAGYSSLNVLKEVPFDVIKIDRSLLGSGEIASVNKSIISSI
HHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
ISLSGDLHMEVLCEGVENATQRNFLLGFGGIQAQGFFYARPMSCQDFEALMEGGATLNPP
HHHCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEECCCCHHHHHHHHHCCCCCCCC
QGGVR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]