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The map label for this gene is ytnA [H]

Identifier: 220903458

GI number: 220903458

Start: 214362

End: 215768

Strand: Direct

Name: ytnA [H]

Synonym: Ddes_0172

Alternate gene names: 220903458

Gene position: 214362-215768 (Clockwise)

Preceding gene: 220903457

Following gene: 220903459

Centisome position: 7.46

GC content: 55.58

Gene sequence:

>1407_bases
ATGTCGAGCGAAAATAAAGGTGTAACTGGTGAAAATCTAACCCGAGGGCTGGAATCGAGACATATCCAGCTTATTGCCAT
CGGCGGCGCCATTGGCGTGGGGCTGTTTCTGGGGTCGAGCACGGCCATCAGAACTGCCGGTCCTGGCTTGTTGCTGTCCT
ATCTTATCGGCGGCATCATCATCTTCTTTGTCATGCGTGCGCTTGGCGAAGTGGCGGTGGCCTATCCCGTGTCAGGCTCG
TTCAGCGCCTATGCCAATATGTTTATGGGGCCGCGCATGGGCTACATAACAGGCTGGACCTACTGGTTCGTGTGGATCGT
GACCGGCATGGCGGAAATTACGGCGGTCGGCGTGTACTGCACCTTCTGGTGGCCGGACTTGCCACAATGGATACCAGCGT
TGCTGGCGCTGGTATGTATGACCACAGTCAACCTCATCTCGGTCAAGCTGTTCGGCGAGTTCGAGTTCTGGTTTGCTCTC
ATCAAGGTTGTGGTCATCATCGCCATGATTGCCATCGGTCTTGGTATCATTCTGTTCGGTATCGGCCACGGTGGCGTACC
CACGGGCATCAGCAACCTGTACGCCCTTGAAGGCGGCTTTCTGCCCAACGGCATGACCGGCGTATTCATGGCGCTTTCAA
TGGTCATGTTCGCCTTTGTGGGCATTGAGCTTATCGGCGTTACAGCCGGTGAAGCCTGCAACCCCGAAAAGTCCATCCCC
TCGGCCATCAACAAGGTGCTGTGGCGTATTCTGCTGTTCTATATCGGTGCTCTTTTCGTTATCATGAGTATCTTTCCCTG
GAACGAAATCGGCGTACACGGCAGCCCCTTTGTGCTGACCTTCAAGAACATCGGCATCGCCGCCGCTGCGGGCATCATCA
ACTTTGTGGTGGCCACGGCGGCCCTGTCTTCGTGCAACAGCGGCATCTACAGTAACGGCCGCATGCTGTACAACCTTGCT
CTGCAAAAGCGCGCCCCCCAGTATTTTGCACAGACCAGCAGGGCGAACGTGCCCGCGCGCGGCATCTTGGTGTCTTCGTG
CATCATGCTGATCGGCGTGTTTCTGAACTATATCGTTCCCGAAGAAGTCTTCCTTATCGTAACCAGCGTGGCTACCTTCG
CGGTTGTGTGGATTTGGGCAACCATCATCATAGTGCAGATGAAGTCCCGTCAGAGCAAAAGCCCTGAAGAGGCGGCTGCC
GTCAAATACAAGATGCCCTGGTATCCCTACTCCAACTACTTCGCGCTGGCCGGGCTGGTTTGCGTTTACGTGATTCTCAG
CCTCGGTGAGTCCACCCGCATCGCCATGATAGTGGGTCCCATATGGATTATCGGCATTAACGTGGTCTACAACCTGCTCG
GCTGGAACAAAAAAGACGCGCAGCCAGGCCTTGGTGCCGAAAGCTAG

Upstream 100 bases:

>100_bases
ACAACATGCCAAAGAGGAAAAAGGAGGTCCCCCCACTCACAAACCCTCGTTGTCAAAGGATTCGCATTCAAATTCGTTCA
AGGTTTTGCAAGGAGACCAT

Downstream 100 bases:

>100_bases
GGCGCACACAGCAATGCTGCGGCGCGAAATTCGAGTGTGCGTTTCGCATTGCCGGTTTTTTGCAGAGGATCGACTCCGCA
TGAAAATAACGGACGCAGCA

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSSENKGVTGENLTRGLESRHIQLIAIGGAIGVGLFLGSSTAIRTAGPGLLLSYLIGGIIIFFVMRALGEVAVAYPVSGS
FSAYANMFMGPRMGYITGWTYWFVWIVTGMAEITAVGVYCTFWWPDLPQWIPALLALVCMTTVNLISVKLFGEFEFWFAL
IKVVVIIAMIAIGLGIILFGIGHGGVPTGISNLYALEGGFLPNGMTGVFMALSMVMFAFVGIELIGVTAGEACNPEKSIP
SAINKVLWRILLFYIGALFVIMSIFPWNEIGVHGSPFVLTFKNIGIAAAAGIINFVVATAALSSCNSGIYSNGRMLYNLA
LQKRAPQYFAQTSRANVPARGILVSSCIMLIGVFLNYIVPEEVFLIVTSVATFAVVWIWATIIIVQMKSRQSKSPEEAAA
VKYKMPWYPYSNYFALAGLVCVYVILSLGESTRIAMIVGPIWIIGINVVYNLLGWNKKDAQPGLGAES

Sequences:

>Translated_468_residues
MSSENKGVTGENLTRGLESRHIQLIAIGGAIGVGLFLGSSTAIRTAGPGLLLSYLIGGIIIFFVMRALGEVAVAYPVSGS
FSAYANMFMGPRMGYITGWTYWFVWIVTGMAEITAVGVYCTFWWPDLPQWIPALLALVCMTTVNLISVKLFGEFEFWFAL
IKVVVIIAMIAIGLGIILFGIGHGGVPTGISNLYALEGGFLPNGMTGVFMALSMVMFAFVGIELIGVTAGEACNPEKSIP
SAINKVLWRILLFYIGALFVIMSIFPWNEIGVHGSPFVLTFKNIGIAAAAGIINFVVATAALSSCNSGIYSNGRMLYNLA
LQKRAPQYFAQTSRANVPARGILVSSCIMLIGVFLNYIVPEEVFLIVTSVATFAVVWIWATIIIVQMKSRQSKSPEEAAA
VKYKMPWYPYSNYFALAGLVCVYVILSLGESTRIAMIVGPIWIIGINVVYNLLGWNKKDAQPGLGAES
>Mature_467_residues
SSENKGVTGENLTRGLESRHIQLIAIGGAIGVGLFLGSSTAIRTAGPGLLLSYLIGGIIIFFVMRALGEVAVAYPVSGSF
SAYANMFMGPRMGYITGWTYWFVWIVTGMAEITAVGVYCTFWWPDLPQWIPALLALVCMTTVNLISVKLFGEFEFWFALI
KVVVIIAMIAIGLGIILFGIGHGGVPTGISNLYALEGGFLPNGMTGVFMALSMVMFAFVGIELIGVTAGEACNPEKSIPS
AINKVLWRILLFYIGALFVIMSIFPWNEIGVHGSPFVLTFKNIGIAAAAGIINFVVATAALSSCNSGIYSNGRMLYNLAL
QKRAPQYFAQTSRANVPARGILVSSCIMLIGVFLNYIVPEEVFLIVTSVATFAVVWIWATIIIVQMKSRQSKSPEEAAAV
KYKMPWYPYSNYFALAGLVCVYVILSLGESTRIAMIVGPIWIIGINVVYNLLGWNKKDAQPGLGAES

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI110347453, Length=353, Percent_Identity=26.9121813031161, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI181337167, Length=362, Percent_Identity=23.7569060773481, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI48994972, Length=464, Percent_Identity=49.7844827586207, Blast_Score=449, Evalue=1e-127,
Organism=Escherichia coli, GI1786602, Length=468, Percent_Identity=50, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1786302, Length=441, Percent_Identity=45.578231292517, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI1786789, Length=454, Percent_Identity=43.6123348017621, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1790653, Length=464, Percent_Identity=43.1034482758621, Blast_Score=381, Evalue=1e-107,
Organism=Escherichia coli, GI87081915, Length=405, Percent_Identity=42.962962962963, Blast_Score=337, Evalue=1e-93,
Organism=Escherichia coli, GI87081708, Length=439, Percent_Identity=37.5854214123007, Blast_Score=298, Evalue=4e-82,
Organism=Escherichia coli, GI1788480, Length=448, Percent_Identity=38.1696428571429, Blast_Score=272, Evalue=4e-74,
Organism=Escherichia coli, GI1789017, Length=449, Percent_Identity=33.630289532294, Blast_Score=261, Evalue=7e-71,
Organism=Escherichia coli, GI87081869, Length=192, Percent_Identity=22.3958333333333, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324061, Length=437, Percent_Identity=33.4096109839817, Blast_Score=227, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6320772, Length=412, Percent_Identity=35.6796116504854, Blast_Score=220, Evalue=4e-58,
Organism=Saccharomyces cerevisiae, GI6322892, Length=395, Percent_Identity=34.6835443037975, Blast_Score=207, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6324990, Length=443, Percent_Identity=31.6027088036117, Blast_Score=193, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6324059, Length=364, Percent_Identity=35.4395604395604, Blast_Score=185, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6324924, Length=412, Percent_Identity=31.7961165048544, Blast_Score=183, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6324553, Length=399, Percent_Identity=32.5814536340852, Blast_Score=178, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6319824, Length=400, Percent_Identity=27.25, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6321629, Length=414, Percent_Identity=26.3285024154589, Blast_Score=165, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6320717, Length=407, Percent_Identity=26.5356265356265, Blast_Score=163, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6319542, Length=398, Percent_Identity=27.3869346733668, Blast_Score=160, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6321053, Length=417, Percent_Identity=28.2973621103118, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6320251, Length=399, Percent_Identity=25.8145363408521, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6319543, Length=406, Percent_Identity=27.0935960591133, Blast_Score=156, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6319608, Length=359, Percent_Identity=28.133704735376, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6320364, Length=516, Percent_Identity=26.5503875968992, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6322967, Length=418, Percent_Identity=25.1196172248804, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6324981, Length=401, Percent_Identity=25.9351620947631, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24667468, Length=283, Percent_Identity=27.5618374558304, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI221512776, Length=367, Percent_Identity=22.3433242506812, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24666159, Length=367, Percent_Identity=22.3433242506812, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24668806, Length=311, Percent_Identity=23.1511254019293, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21356285, Length=311, Percent_Identity=23.1511254019293, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24668802, Length=311, Percent_Identity=23.1511254019293, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI161077963, Length=424, Percent_Identity=23.1132075471698, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50556; Mature: 50424

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSENKGVTGENLTRGLESRHIQLIAIGGAIGVGLFLGSSTAIRTAGPGLLLSYLIGGII
CCCCCCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCCEEECCCHHHHHHHHHHHHH
IFFVMRALGEVAVAYPVSGSFSAYANMFMGPRMGYITGWTYWFVWIVTGMAEITAVGVYC
HHHHHHHHHHEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEE
TFWWPDLPQWIPALLALVCMTTVNLISVKLFGEFEFWFALIKVVVIIAMIAIGLGIILFG
EEECCCHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGHGGVPTGISNLYALEGGFLPNGMTGVFMALSMVMFAFVGIELIGVTAGEACNPEKSIP
CCCCCCCCCHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHH
SAINKVLWRILLFYIGALFVIMSIFPWNEIGVHGSPFVLTFKNIGIAAAAGIINFVVATA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHH
ALSSCNSGIYSNGRMLYNLALQKRAPQYFAQTSRANVPARGILVSSCIMLIGVFLNYIVP
HHHHHCCCCCCCCEEEEEHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCH
EEVFLIVTSVATFAVVWIWATIIIVQMKSRQSKSPEEAAAVKYKMPWYPYSNYFALAGLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEECCCCCCCHHHHHHHHH
CVYVILSLGESTRIAMIVGPIWIIGINVVYNLLGWNKKDAQPGLGAES
HHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SSENKGVTGENLTRGLESRHIQLIAIGGAIGVGLFLGSSTAIRTAGPGLLLSYLIGGII
CCCCCCCCHHHHHHHHHHCCEEEEEECCHHHHHHHHCCCCEEECCCHHHHHHHHHHHHH
IFFVMRALGEVAVAYPVSGSFSAYANMFMGPRMGYITGWTYWFVWIVTGMAEITAVGVYC
HHHHHHHHHHEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEE
TFWWPDLPQWIPALLALVCMTTVNLISVKLFGEFEFWFALIKVVVIIAMIAIGLGIILFG
EEECCCHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGHGGVPTGISNLYALEGGFLPNGMTGVFMALSMVMFAFVGIELIGVTAGEACNPEKSIP
CCCCCCCCCHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHH
SAINKVLWRILLFYIGALFVIMSIFPWNEIGVHGSPFVLTFKNIGIAAAAGIINFVVATA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHH
ALSSCNSGIYSNGRMLYNLALQKRAPQYFAQTSRANVPARGILVSSCIMLIGVFLNYIVP
HHHHHCCCCCCCCEEEEEHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCH
EEVFLIVTSVATFAVVWIWATIIIVQMKSRQSKSPEEAAAVKYKMPWYPYSNYFALAGLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEECCCCCCCHHHHHHHHH
CVYVILSLGESTRIAMIVGPIWIIGINVVYNLLGWNKKDAQPGLGAES
HHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]