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The map label for this gene is alr

Identifier: 220903457

GI number: 220903457

Start: 213021

End: 214136

Strand: Direct

Name: alr

Synonym: Ddes_0171

Alternate gene names: 220903457

Gene position: 213021-214136 (Clockwise)

Preceding gene: 220903456

Following gene: 220903458

Centisome position: 7.41

GC content: 59.95

Gene sequence:

>1116_bases
GTGGTCAGTTTTGACAGGCCCGTGTGGGCAGAAATAGATCTTTCGGCCTTTCGCCATAATATGCGGCAGATCAAGTCGCT
TCTTCAGCCAGGCACAATCTTTTGCCCCATTATCAAGGCTGACGGCTACGGCCACGGAGCCGTGCCTCTGGCGCATGAGG
CAGTAGCCATGGGGGCGGGCTACCTCGGCGTGGCTATTCTGGACGAGGCCGCGGCCCTGCGCGCGGCGGGCATAACCCTG
CCCATTCTCATTCTCGGCTATACGCCGCCCCAGGCTGCTGCCTTTGTGGTCAGTAACCACATTACCCAGACCATTTTCAG
CAAGGAACAGGCCGATGCCCTGTCTGCCGCGGCCAGTAACCTGGGCATCACCGTCAAGGTTCACGTCAAGGTGGATACCG
GCATGACCAGAATCGGCGTGCGGCCCGAAGAGGCTGCGGCGTTCTGCTCATATGTGGCCGGACTTGAAAACGTGCATCTT
GAAGGCATGTTCACGCACTTTGCCAGTTCCGACAGCGCCGACCATGCGTACTGTCTTGAGCAGTTCGGGCGGTTTACGGC
GGCCATTGCCGCTGTGGAGGCCTCGGGCATTCGACTAGGCATCCGGCACTGTGCCAACAGCGCCGCCATATTGTCCCTGC
CTGAAGGTCATCTTGATATGGTCCGGGCAGGGATAATTCTTTATGGCCTCAAGCCGTCCGACGAATGCCCCATGCCCATT
GATCTGCGTCCCGTCATGCGCCTCAAGGCGCGGCTGGCCATGGTCAAGCAGGTTCCGCCCGGCGTGGGCGTGAGCTACGG
CAGCATCTATCACACGCAGAAAGAAAGCAGCCTTGCCACCATCCCCATTGGCTATGCTGACGGATACACGCGCATGCTGA
GCCGCAAGGCGCAGGTGCTGCTGCGTGGGCAGCGTGCCCCGGTGGTGGGCCGTATATGTATGGACCAGTGCATGGTGGAT
GTGAGCCATGTGCCGCAGGCCGCCGTGGGCGACGAGGTGCTTCTTTTCGGCGGGCCTGATCTGCCCGCAGATGAAATTGC
CGCCCATCTGGGTACTATCAACTATGAAGTTGTCTGCATGGTGGGCAAACGTGTGCCAAGGGTATACGTGGAGTAA

Upstream 100 bases:

>100_bases
GATTTTTGTATTCTATTTTGATGTTTCTGACGGTCTTGCACGGGCAAAAAGCCCGTATGCCGGGGCGGTTGCAGTGAGCC
TGCCCGGCACAGGAGGAAAC

Downstream 100 bases:

>100_bases
CGCTTTTCCCCCTTTTGTTGATGCCGCTTGCAATATCTTGCCCGAGGAGAATGCCGCTGCTTGTCGCGGTCATGAAACTT
ACGGTCATATGCGGATGACC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MVSFDRPVWAEIDLSAFRHNMRQIKSLLQPGTIFCPIIKADGYGHGAVPLAHEAVAMGAGYLGVAILDEAAALRAAGITL
PILILGYTPPQAAAFVVSNHITQTIFSKEQADALSAAASNLGITVKVHVKVDTGMTRIGVRPEEAAAFCSYVAGLENVHL
EGMFTHFASSDSADHAYCLEQFGRFTAAIAAVEASGIRLGIRHCANSAAILSLPEGHLDMVRAGIILYGLKPSDECPMPI
DLRPVMRLKARLAMVKQVPPGVGVSYGSIYHTQKESSLATIPIGYADGYTRMLSRKAQVLLRGQRAPVVGRICMDQCMVD
VSHVPQAAVGDEVLLFGGPDLPADEIAAHLGTINYEVVCMVGKRVPRVYVE

Sequences:

>Translated_371_residues
MVSFDRPVWAEIDLSAFRHNMRQIKSLLQPGTIFCPIIKADGYGHGAVPLAHEAVAMGAGYLGVAILDEAAALRAAGITL
PILILGYTPPQAAAFVVSNHITQTIFSKEQADALSAAASNLGITVKVHVKVDTGMTRIGVRPEEAAAFCSYVAGLENVHL
EGMFTHFASSDSADHAYCLEQFGRFTAAIAAVEASGIRLGIRHCANSAAILSLPEGHLDMVRAGIILYGLKPSDECPMPI
DLRPVMRLKARLAMVKQVPPGVGVSYGSIYHTQKESSLATIPIGYADGYTRMLSRKAQVLLRGQRAPVVGRICMDQCMVD
VSHVPQAAVGDEVLLFGGPDLPADEIAAHLGTINYEVVCMVGKRVPRVYVE
>Mature_371_residues
MVSFDRPVWAEIDLSAFRHNMRQIKSLLQPGTIFCPIIKADGYGHGAVPLAHEAVAMGAGYLGVAILDEAAALRAAGITL
PILILGYTPPQAAAFVVSNHITQTIFSKEQADALSAAASNLGITVKVHVKVDTGMTRIGVRPEEAAAFCSYVAGLENVHL
EGMFTHFASSDSADHAYCLEQFGRFTAAIAAVEASGIRLGIRHCANSAAILSLPEGHLDMVRAGIILYGLKPSDECPMPI
DLRPVMRLKARLAMVKQVPPGVGVSYGSIYHTQKESSLATIPIGYADGYTRMLSRKAQVLLRGQRAPVVGRICMDQCMVD
VSHVPQAAVGDEVLLFGGPDLPADEIAAHLGTINYEVVCMVGKRVPRVYVE

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

Organism=Escherichia coli, GI1790487, Length=364, Percent_Identity=34.3406593406593, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1787439, Length=369, Percent_Identity=32.7913279132791, Blast_Score=178, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR_DESDA (B8J2K3)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002478769.1
- GeneID:   7283825
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_0171
- HOGENOM:   HBG712172
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992
- TIGRFAMs:   TIGR00492

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 39628; Mature: 39628

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 39-39 ACT_SITE 266-266

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSFDRPVWAEIDLSAFRHNMRQIKSLLQPGTIFCPIIKADGYGHGAVPLAHEAVAMGAG
CCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCC
YLGVAILDEAAALRAAGITLPILILGYTPPQAAAFVVSNHITQTIFSKEQADALSAAASN
HHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LGITVKVHVKVDTGMTRIGVRPEEAAAFCSYVAGLENVHLEGMFTHFASSDSADHAYCLE
CCEEEEEEEEEECCCEEECCCHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCHHHHHH
QFGRFTAAIAAVEASGIRLGIRHCANSAAILSLPEGHLDMVRAGIILYGLKPSDECPMPI
HHHHHHHHHHHHHHCCEEEEHHHCCCCCEEEECCCCHHHHHHHCEEEEECCCCCCCCCCC
DLRPVMRLKARLAMVKQVPPGVGVSYGSIYHTQKESSLATIPIGYADGYTRMLSRKAQVL
CCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEEEECCCHHHHHHHHHHHHH
LRGQRAPVVGRICMDQCMVDVSHVPQAAVGDEVLLFGGPDLPADEIAAHLGTINYEVVCM
HCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEE
VGKRVPRVYVE
ECCCCCEEECC
>Mature Secondary Structure
MVSFDRPVWAEIDLSAFRHNMRQIKSLLQPGTIFCPIIKADGYGHGAVPLAHEAVAMGAG
CCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHCCC
YLGVAILDEAAALRAAGITLPILILGYTPPQAAAFVVSNHITQTIFSKEQADALSAAASN
HHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LGITVKVHVKVDTGMTRIGVRPEEAAAFCSYVAGLENVHLEGMFTHFASSDSADHAYCLE
CCEEEEEEEEEECCCEEECCCHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCHHHHHH
QFGRFTAAIAAVEASGIRLGIRHCANSAAILSLPEGHLDMVRAGIILYGLKPSDECPMPI
HHHHHHHHHHHHHHCCEEEEHHHCCCCCEEEECCCCHHHHHHHCEEEEECCCCCCCCCCC
DLRPVMRLKARLAMVKQVPPGVGVSYGSIYHTQKESSLATIPIGYADGYTRMLSRKAQVL
CCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEEEECCCHHHHHHHHHHHHH
LRGQRAPVVGRICMDQCMVDVSHVPQAAVGDEVLLFGGPDLPADEIAAHLGTINYEVVCM
HCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEE
VGKRVPRVYVE
ECCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA