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The map label for this gene is modE [H]

Identifier: 220903453

GI number: 220903453

Start: 208332

End: 209456

Strand: Reverse

Name: modE [H]

Synonym: Ddes_0167

Alternate gene names: 220903453

Gene position: 209456-208332 (Counterclockwise)

Preceding gene: 220903462

Following gene: 220903452

Centisome position: 7.29

GC content: 63.2

Gene sequence:

>1125_bases
ATGGAAAAAAACAAAAACCGTGAGGAAATGGCCGCGCTTTTGCGTACGCTCTCTTCCGCGGACCGGGCGTGGCTGCGCCA
GCGGCTTATGCGCCGCGACTCCGCCGCCCTGTTGCAGGATACCGGCCGCATCAGTCCCAGAGAACTGCTGGCAGTGGAAT
CATGGCTGTGGGAACGGGCCGCGGCAGCGCGCGGCCCGCGCGAAAAGCGCCCAAGACTGCGCATGTGGCTCATCTTCATG
CTCTTGCGCTATGCCGCCCTGCGGCTGGTGGAAATTTTCAGCCTCAAGCCGGGCCATATGGATCTGCAGGAAGGCATCAT
CCGCCTGCCTGACAATAACGGCAGCCCGGGCCGTGAGGTTCCCCTGCCCCTTACCGTGAGCCGCCGCCTGCGGCGCGTGC
TGGAAGATCCCGCTCTTTTTCCTGAAAGCCACGATCTTCTGCGCTGCGATGCAAGCTATGTGCGTCGCTGCCTGCAGCAG
TGCGGAGCCGCCTGCGGACTGCCCAAAGGCCTGCTGAGCGCGCGTGCCCTGCGCCACAGCCGCGCTCTGGAACTGGGGCG
GCAGGGCCTGCCCCTGCCCGTGGTGGATATTTTTCTGGGGCGCCGCGCCGCGCCGGGACAGAGCGGCATTGTACGCTGCG
ACCTGCAGGAGGCGAGACGCCTTCTGCGAGAACAACTGCAAAGGGAGCGGCCGATGAAAACCAGCGCCAGAAACGTTTTT
CAAGGTCGCATCACGTCGCTGCGCCAGACCGGCATTATGGTGGAAGTAGCCATGCGCACGGCGGGCGGCCTGCGAATTGT
ATCGCTTATTACGGATGAAAGCTGTCGCACGCTGGCTCTGGCCGAAGGCAAGCTGGTCAATGCCAGCGTAAAGGCCCCCT
GGGTGCTGGTCGCGCCGGGGGAAATGCCAAAAAACACGGCTCCTCCGGCGGAAAACTGCTTTGTGGGCGTGGTGGAACGC
GTGCGTGAAGACCAGATGGTGGCCGAGGTGCTGGTGGCCCTGCCGGAAGGCAGTCTGGTATGCGCCATCCAGAGCGGCGG
GCAGAACCCCGCCTGCGGGCTGAAGGCCGGACAGAAAGCCACTGTGCTTTTCAAATCTTTTTCTGTCATCCTCAATCTGG
ACTAA

Upstream 100 bases:

>100_bases
CTTGTCCGGGCAAGGAGATCACGATTTACATAAAAAGCGTGAACACTATACAACCCGGCATATTTTTATGTATAAGACCT
AAAAAATGACAGGATACGGC

Downstream 100 bases:

>100_bases
CGGCTGTTCCCAAACCTGCCCGATATATTCCGGCGCGGCAGTGTCCACACGCTGCCGCGTCCTGAAATATTTTACCTTTG
ATAATCTGCCTTCTTAAAGG

Product: TOBE domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MEKNKNREEMAALLRTLSSADRAWLRQRLMRRDSAALLQDTGRISPRELLAVESWLWERAAAARGPREKRPRLRMWLIFM
LLRYAALRLVEIFSLKPGHMDLQEGIIRLPDNNGSPGREVPLPLTVSRRLRRVLEDPALFPESHDLLRCDASYVRRCLQQ
CGAACGLPKGLLSARALRHSRALELGRQGLPLPVVDIFLGRRAAPGQSGIVRCDLQEARRLLREQLQRERPMKTSARNVF
QGRITSLRQTGIMVEVAMRTAGGLRIVSLITDESCRTLALAEGKLVNASVKAPWVLVAPGEMPKNTAPPAENCFVGVVER
VREDQMVAEVLVALPEGSLVCAIQSGGQNPACGLKAGQKATVLFKSFSVILNLD

Sequences:

>Translated_374_residues
MEKNKNREEMAALLRTLSSADRAWLRQRLMRRDSAALLQDTGRISPRELLAVESWLWERAAAARGPREKRPRLRMWLIFM
LLRYAALRLVEIFSLKPGHMDLQEGIIRLPDNNGSPGREVPLPLTVSRRLRRVLEDPALFPESHDLLRCDASYVRRCLQQ
CGAACGLPKGLLSARALRHSRALELGRQGLPLPVVDIFLGRRAAPGQSGIVRCDLQEARRLLREQLQRERPMKTSARNVF
QGRITSLRQTGIMVEVAMRTAGGLRIVSLITDESCRTLALAEGKLVNASVKAPWVLVAPGEMPKNTAPPAENCFVGVVER
VREDQMVAEVLVALPEGSLVCAIQSGGQNPACGLKAGQKATVLFKSFSVILNLD
>Mature_374_residues
MEKNKNREEMAALLRTLSSADRAWLRQRLMRRDSAALLQDTGRISPRELLAVESWLWERAAAARGPREKRPRLRMWLIFM
LLRYAALRLVEIFSLKPGHMDLQEGIIRLPDNNGSPGREVPLPLTVSRRLRRVLEDPALFPESHDLLRCDASYVRRCLQQ
CGAACGLPKGLLSARALRHSRALELGRQGLPLPVVDIFLGRRAAPGQSGIVRCDLQEARRLLREQLQRERPMKTSARNVF
QGRITSLRQTGIMVEVAMRTAGGLRIVSLITDESCRTLALAEGKLVNASVKAPWVLVAPGEMPKNTAPPAENCFVGVVER
VREDQMVAEVLVALPEGSLVCAIQSGGQNPACGLKAGQKATVLFKSFSVILNLD

Specific function: Involved in the transport of molybdenum into the cell. May have a role in the early intracellular capture or metabolism of molybdenum [H]

COG id: COG2005

COG function: function code R; N-terminal domain of molybdenum-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the modE family [H]

Homologues:

Organism=Escherichia coli, GI1786976, Length=141, Percent_Identity=35.4609929078014, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR004606
- InterPro:   IPR008995
- InterPro:   IPR003725
- InterPro:   IPR016462
- InterPro:   IPR005116
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03459 TOBE [H]

EC number: NA

Molecular weight: Translated: 41552; Mature: 41552

Theoretical pI: Translated: 10.95; Mature: 10.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNKNREEMAALLRTLSSADRAWLRQRLMRRDSAALLQDTGRISPRELLAVESWLWERA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AAARGPREKRPRLRMWLIFMLLRYAALRLVEIFSLKPGHMDLQEGIIRLPDNNGSPGREV
HHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCEEECCCCCCCCCCCC
PLPLTVSRRLRRVLEDPALFPESHDLLRCDASYVRRCLQQCGAACGLPKGLLSARALRHS
CCCHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHCHHCCCCHHHHHHHHHHHH
RALELGRQGLPLPVVDIFLGRRAAPGQSGIVRCDLQEARRLLREQLQRERPMKTSARNVF
HHHHHCCCCCCCHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCHHHHHHHH
QGRITSLRQTGIMVEVAMRTAGGLRIVSLITDESCRTLALAEGKLVNASVKAPWVLVAPG
HHHHHHHHHCCCEEEEEHHCCCCEEEEEEEECCCCCEEEEECCCEEECCCCCCEEEECCC
EMPKNTAPPAENCFVGVVERVREDQMVAEVLVALPEGSLVCAIQSGGQNPACGLKAGQKA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCC
TVLFKSFSVILNLD
EEHEEEEEEEEECC
>Mature Secondary Structure
MEKNKNREEMAALLRTLSSADRAWLRQRLMRRDSAALLQDTGRISPRELLAVESWLWERA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
AAARGPREKRPRLRMWLIFMLLRYAALRLVEIFSLKPGHMDLQEGIIRLPDNNGSPGREV
HHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCEEECCCCCCCCCCCC
PLPLTVSRRLRRVLEDPALFPESHDLLRCDASYVRRCLQQCGAACGLPKGLLSARALRHS
CCCHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHCHHCCCCHHHHHHHHHHHH
RALELGRQGLPLPVVDIFLGRRAAPGQSGIVRCDLQEARRLLREQLQRERPMKTSARNVF
HHHHHCCCCCCCHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCHHHHHHHH
QGRITSLRQTGIMVEVAMRTAGGLRIVSLITDESCRTLALAEGKLVNASVKAPWVLVAPG
HHHHHHHHHCCCEEEEEHHCCCCEEEEEEEECCCCCEEEEECCCEEECCCCCCEEEECCC
EMPKNTAPPAENCFVGVVERVREDQMVAEVLVALPEGSLVCAIQSGGQNPACGLKAGQKA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCC
TVLFKSFSVILNLD
EEHEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8384683; 7665518 [H]