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The map label for this gene is mcp4 [H]

Identifier: 220903452

GI number: 220903452

Start: 205832

End: 207637

Strand: Reverse

Name: mcp4 [H]

Synonym: Ddes_0166

Alternate gene names: 220903452

Gene position: 207637-205832 (Counterclockwise)

Preceding gene: 220903453

Following gene: 220903450

Centisome position: 7.23

GC content: 59.3

Gene sequence:

>1806_bases
ATGAACGTAAAAGCGTGGCTTGTTACACTTTGTCTGGCTTTCACCCTGGGTATGGGAATACTGTTTTTCAGCAACATGTA
CATCTCAAAGCTGGTGCTCGACGATATAACCCTGCCGCAGATATCCGCGGCGCTGAAAGCAAAATACGAATATGGACTCA
AGCATACGGTGGAACTTGCCGCGCAGACCCTTGCCCGCAGTCTTGAAGATGCGGCCAGCCCGGAAGAAAAATACGCCCTC
ATCGGAGAACTTACAGACTTTCAGCGTTTTTTCCCCGATGAAGAAGGCTACCTGTTTACCTACAAGACAGACGGAACGCG
CATAAACGTGCCGATCAACAAATCCCAGAACGGAAAAAACTTTATTGACCTGAAAGATCCCAACGGGGTTCCCTTTATCC
GCGATCTTATTGATGCTGCCCGGAAAGGCGGCGGTTTTGTCCTTTACCATTTTGAAAAAGCGGGAGCGGGCGTACAGCCC
AAGCTGAGCTACGCGCAGCTTGTTCCGGGTACGGATGTCATTATCGGCACGGGCGTATACATTGACGGCGTTGACAAGGA
ACGCAGCCGCATAACCAGCCTGGTCACTGAAAGCCAGAATCACTACAGCCGGGTGCAGGCCGCGCTTGGCGCGGGCATTC
TTGCGCTGATCCTGTGTATTGCCTGGGGCGTGACCCGCCGCATCTGTCCTCCGCTGCTCCAGCTTACCGCCGAGGCCGAA
GAGGTGGCCGCCGGGCGCCTGGATCACCTCACAACCATAAAGCCTTCAAGCCCTCTGGAAATCCGCGCCCTGCACGCTTC
GCTCAAAATCATGATAACAAACCTGCACAGCCGTGTGCAGGAGGCAGCGCAAAAAACCCTTGAGGCCGCAGAAGCGCTGG
AGCAGGCCAAAACCGCGCAGGATCGGGCCGAAAAGGCGCAGGCGCAGGCTGAAACCGCGCGCAGGGACGGCATGCTGGCC
GCTGCCGGACAGCTTGAAGGTATTGCCGGGGTGCTCTCTTCGGCATCTACCGAGCTTTCGGCACAGATTGAGCAGTCTGA
CAAGGGCGCGGCAGAATCGTCGCAGCGCCTTGCGGAGGCAGCCACCGCCATGAACGAAATGAACGCCACCGTGCAGGAAG
TAGCCCAAAACGCCGGCATGGCTTCCGGAGCATCCATGGATACCCGCGACAAGGCCCTGACGGGCGCGCGCATCGTGCAT
GACGCCATGAACAGCATCGCCCGTGTGCAGGAACACTCCCTGGCGCTCAAGGACGATATGGCCCGGCTCAACGAGCATGC
CCTGGCTATCAGCAGAATCATGAACGTCATTTCAGACATCGCGGACCAGACCAACCTGCTGGCCCTCAACGCCGCCATCG
AGGCTGCCCGCGCCGGTGACGCCGGACGCGGCTTCGCCGTGGTGGCCGACGAGGTGCGCAAGCTGGCCGAAAAAACCATG
ACGTCCACCAGCGACGTGGCGGAAGCCATACGCGCCATTCAGGAAAGCACGCGGCAAAGCATGACCGGGGTGGAAAACGC
CGTCAACGCCATCGGTGAGGCCACGGGCCTGGCCGGGCAGTCCGGCGCGGCCCTCGAGGGAATTGTGACCACTATCGAGG
AAACCACAGACCAGATTAACGCCATCGCCGCCGCCAGCGAAGAGCAGTCCGCCGCCAGCGAAGAGATCAACAGAAGCATT
GTGGAAGTAAACGACATGTCACGCCACACCGCCATAGCCATGGGCGAGGCCGCCAGTGCCGTGACCGGCCTTGCGGCGCA
GGCGCAAAAACTTGCGGAGCTTATCCAGGACATGAAGCGGGCCTAG

Upstream 100 bases:

>100_bases
TACAGATTTCCTGCAGCATCCGGCCGCACCGCCATTTCTGCGGCCCGCTGCTTTTTTTACCCGCGACATATTGTCACACA
TCACACGTCGAGGCATCAAC

Downstream 100 bases:

>100_bases
AGGGCCGTTTTTAAGCCGCCCTCAACCACCGTACCATTCCGGGCGCATGTCCGGCACATCTGCCGCCTTGCCCTGCCAGA
GGTCACGGGCGGTCAGGGCG

Product: Cache sensor-containing methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 601; Mature: 601

Protein sequence:

>601_residues
MNVKAWLVTLCLAFTLGMGILFFSNMYISKLVLDDITLPQISAALKAKYEYGLKHTVELAAQTLARSLEDAASPEEKYAL
IGELTDFQRFFPDEEGYLFTYKTDGTRINVPINKSQNGKNFIDLKDPNGVPFIRDLIDAARKGGGFVLYHFEKAGAGVQP
KLSYAQLVPGTDVIIGTGVYIDGVDKERSRITSLVTESQNHYSRVQAALGAGILALILCIAWGVTRRICPPLLQLTAEAE
EVAAGRLDHLTTIKPSSPLEIRALHASLKIMITNLHSRVQEAAQKTLEAAEALEQAKTAQDRAEKAQAQAETARRDGMLA
AAGQLEGIAGVLSSASTELSAQIEQSDKGAAESSQRLAEAATAMNEMNATVQEVAQNAGMASGASMDTRDKALTGARIVH
DAMNSIARVQEHSLALKDDMARLNEHALAISRIMNVISDIADQTNLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTM
TSTSDVAEAIRAIQESTRQSMTGVENAVNAIGEATGLAGQSGAALEGIVTTIEETTDQINAIAAASEEQSAASEEINRSI
VEVNDMSRHTAIAMGEAASAVTGLAAQAQKLAELIQDMKRA

Sequences:

>Translated_601_residues
MNVKAWLVTLCLAFTLGMGILFFSNMYISKLVLDDITLPQISAALKAKYEYGLKHTVELAAQTLARSLEDAASPEEKYAL
IGELTDFQRFFPDEEGYLFTYKTDGTRINVPINKSQNGKNFIDLKDPNGVPFIRDLIDAARKGGGFVLYHFEKAGAGVQP
KLSYAQLVPGTDVIIGTGVYIDGVDKERSRITSLVTESQNHYSRVQAALGAGILALILCIAWGVTRRICPPLLQLTAEAE
EVAAGRLDHLTTIKPSSPLEIRALHASLKIMITNLHSRVQEAAQKTLEAAEALEQAKTAQDRAEKAQAQAETARRDGMLA
AAGQLEGIAGVLSSASTELSAQIEQSDKGAAESSQRLAEAATAMNEMNATVQEVAQNAGMASGASMDTRDKALTGARIVH
DAMNSIARVQEHSLALKDDMARLNEHALAISRIMNVISDIADQTNLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTM
TSTSDVAEAIRAIQESTRQSMTGVENAVNAIGEATGLAGQSGAALEGIVTTIEETTDQINAIAAASEEQSAASEEINRSI
VEVNDMSRHTAIAMGEAASAVTGLAAQAQKLAELIQDMKRA
>Mature_601_residues
MNVKAWLVTLCLAFTLGMGILFFSNMYISKLVLDDITLPQISAALKAKYEYGLKHTVELAAQTLARSLEDAASPEEKYAL
IGELTDFQRFFPDEEGYLFTYKTDGTRINVPINKSQNGKNFIDLKDPNGVPFIRDLIDAARKGGGFVLYHFEKAGAGVQP
KLSYAQLVPGTDVIIGTGVYIDGVDKERSRITSLVTESQNHYSRVQAALGAGILALILCIAWGVTRRICPPLLQLTAEAE
EVAAGRLDHLTTIKPSSPLEIRALHASLKIMITNLHSRVQEAAQKTLEAAEALEQAKTAQDRAEKAQAQAETARRDGMLA
AAGQLEGIAGVLSSASTELSAQIEQSDKGAAESSQRLAEAATAMNEMNATVQEVAQNAGMASGASMDTRDKALTGARIVH
DAMNSIARVQEHSLALKDDMARLNEHALAISRIMNVISDIADQTNLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTM
TSTSDVAEAIRAIQESTRQSMTGVENAVNAIGEATGLAGQSGAALEGIVTTIEETTDQINAIAAASEEQSAASEEINRSI
VEVNDMSRHTAIAMGEAASAVTGLAAQAQKLAELIQDMKRA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=350, Percent_Identity=27.4285714285714, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1788194, Length=371, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI2367378, Length=357, Percent_Identity=26.6106442577031, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787690, Length=389, Percent_Identity=30.3341902313625, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789453, Length=232, Percent_Identity=30.1724137931034, Blast_Score=86, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 63977; Mature: 63977

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVKAWLVTLCLAFTLGMGILFFSNMYISKLVLDDITLPQISAALKAKYEYGLKHTVELA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHH
AQTLARSLEDAASPEEKYALIGELTDFQRFFPDEEGYLFTYKTDGTRINVPINKSQNGKN
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCE
FIDLKDPNGVPFIRDLIDAARKGGGFVLYHFEKAGAGVQPKLSYAQLVPGTDVIIGTGVY
EEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHCCCCCEEEECCEE
IDGVDKERSRITSLVTESQNHYSRVQAALGAGILALILCIAWGVTRRICPPLLQLTAEAE
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
EVAAGRLDHLTTIKPSSPLEIRALHASLKIMITNLHSRVQEAAQKTLEAAEALEQAKTAQ
HHHHCCHHHCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRAEKAQAQAETARRDGMLAAAGQLEGIAGVLSSASTELSAQIEQSDKGAAESSQRLAEA
HHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHH
ATAMNEMNATVQEVAQNAGMASGASMDTRDKALTGARIVHDAMNSIARVQEHSLALKDDM
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARLNEHALAISRIMNVISDIADQTNLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTM
HHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
TSTSDVAEAIRAIQESTRQSMTGVENAVNAIGEATGLAGQSGAALEGIVTTIEETTDQIN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
AIAAASEEQSAASEEINRSIVEVNDMSRHTAIAMGEAASAVTGLAAQAQKLAELIQDMKR
HHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
A
C
>Mature Secondary Structure
MNVKAWLVTLCLAFTLGMGILFFSNMYISKLVLDDITLPQISAALKAKYEYGLKHTVELA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHH
AQTLARSLEDAASPEEKYALIGELTDFQRFFPDEEGYLFTYKTDGTRINVPINKSQNGKN
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCE
FIDLKDPNGVPFIRDLIDAARKGGGFVLYHFEKAGAGVQPKLSYAQLVPGTDVIIGTGVY
EEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHCCCCCEEEECCEE
IDGVDKERSRITSLVTESQNHYSRVQAALGAGILALILCIAWGVTRRICPPLLQLTAEAE
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
EVAAGRLDHLTTIKPSSPLEIRALHASLKIMITNLHSRVQEAAQKTLEAAEALEQAKTAQ
HHHHCCHHHCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRAEKAQAQAETARRDGMLAAAGQLEGIAGVLSSASTELSAQIEQSDKGAAESSQRLAEA
HHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHH
ATAMNEMNATVQEVAQNAGMASGASMDTRDKALTGARIVHDAMNSIARVQEHSLALKDDM
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARLNEHALAISRIMNVISDIADQTNLLALNAAIEAARAGDAGRGFAVVADEVRKLAEKTM
HHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
TSTSDVAEAIRAIQESTRQSMTGVENAVNAIGEATGLAGQSGAALEGIVTTIEETTDQIN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
AIAAASEEQSAASEEINRSIVEVNDMSRHTAIAMGEAASAVTGLAAQAQKLAELIQDMKR
HHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]