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The map label for this gene is mrdB [H]

Identifier: 220903446

GI number: 220903446

Start: 198340

End: 199446

Strand: Reverse

Name: mrdB [H]

Synonym: Ddes_0160

Alternate gene names: 220903446

Gene position: 199446-198340 (Counterclockwise)

Preceding gene: 220903447

Following gene: 220903445

Centisome position: 6.94

GC content: 57.0

Gene sequence:

>1107_bases
ATGGACAAAAGTCTGTTCAGCTATATCAACTGGGGCCTGCTGGCCTGCATGCTGCTGCTCTATCTTGTGGGTGTGGGCAA
CCTGTATTCGGCCAGCGGCACGCGGGTGGAAACCGGTCTGGCTTTCAACAGTTTTTACCAGCGGCAGATTATCTGGGGCC
TGTGCGGCCTGGCCTGCATGTTGCTTGCAATGACCTTTGACTACCGGCAATTGCGCAACCTGGCATGGCCGTTCTTTTTT
CTGACCATGCTGCTTCTGCTGCTTGTTCCCATTGCGGGCAAGACCGTTTACGGGGCCAAACGCTGGCTTTCGCTGGGTTT
CATGAGTGTGCAGCCTTCTGAGCTGGCCAAACTTTCCGTGCTGGTGCTGGCCGCGCGCCTGCTTGCGCGCGACGGCCGCC
CGCTGGGCTGGAAAGATTTTATCTCCATAGCCTTTATCTGCCTGCTGCCCTGCGCGCTCATCGTCGTCCAGCCCGACCTC
GGCACAACCATGCTGATCCTGCTTATTCTGGCAGGCATGATCCTGTTTCACGGTCTCAAGGGCTATGTGCTCAAAACCTG
CCTGCTTGCCGTGCCCTGCTTCGGAGCCTTCATGTGGCTTGTGGGCATGCACGACTACCAGCGCCAGCGCATCCTGACCT
TTCTTGACCCCACCACAGACCCGCGCGGAACGGGCTACCACATCATCCAGTCGCGCATTGCCATCGGCTCGGGCGAACTC
TGGGGCAAAGGCTTCAAGGAAGGTACGCAAAGCCAGCTGCGCTTTCTGCCCGAGCGGCATTCCGACTTTGCCGTGGCAGT
TTTCGGGGAAGAATGGGGTTTTGTGGGCTGCGTGGCCCTGGTAACCCTGTTCTGCCTGTTTCTGCTGTCCATTTTTTCCA
CCGCCGCACAGGCCAAAGACCGTTTTGGCAGCATGCTGGTAGTAGGGGTATTTTTTTACTTTTTCTGGCAGATACTCATC
AATATGGGTATGGTCATAGGCATCATGCCGGTGGTGGGCATTCCACTGCCCTTCATCAGCTATGGCGGCAGCGCCACCGT
AGTTAATTTCACGCTGCTGGGCATTGTGCTCAACGTGTCCATGCGGCGCTTCATGTTCAAGGGATAA

Upstream 100 bases:

>100_bases
CGCCGTGGCGGCGCATCCGGCGGCGCAAAACGCAGGAAGTACGGCGATCCAACAGCCATAGACCACGCAAGTGTACGTTT
TTTTGACCAGGTAAGACCGT

Downstream 100 bases:

>100_bases
TTGTCAATCCAACGGGGAGTTCGCTGTGGCCAAGGACGAAATAGCCTATCTCGGTTCCGATACGGTTTACGAAGGAAAAC
TGCATTTCAAGGGCACTGTG

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MDKSLFSYINWGLLACMLLLYLVGVGNLYSASGTRVETGLAFNSFYQRQIIWGLCGLACMLLAMTFDYRQLRNLAWPFFF
LTMLLLLLVPIAGKTVYGAKRWLSLGFMSVQPSELAKLSVLVLAARLLARDGRPLGWKDFISIAFICLLPCALIVVQPDL
GTTMLILLILAGMILFHGLKGYVLKTCLLAVPCFGAFMWLVGMHDYQRQRILTFLDPTTDPRGTGYHIIQSRIAIGSGEL
WGKGFKEGTQSQLRFLPERHSDFAVAVFGEEWGFVGCVALVTLFCLFLLSIFSTAAQAKDRFGSMLVVGVFFYFFWQILI
NMGMVIGIMPVVGIPLPFISYGGSATVVNFTLLGIVLNVSMRRFMFKG

Sequences:

>Translated_368_residues
MDKSLFSYINWGLLACMLLLYLVGVGNLYSASGTRVETGLAFNSFYQRQIIWGLCGLACMLLAMTFDYRQLRNLAWPFFF
LTMLLLLLVPIAGKTVYGAKRWLSLGFMSVQPSELAKLSVLVLAARLLARDGRPLGWKDFISIAFICLLPCALIVVQPDL
GTTMLILLILAGMILFHGLKGYVLKTCLLAVPCFGAFMWLVGMHDYQRQRILTFLDPTTDPRGTGYHIIQSRIAIGSGEL
WGKGFKEGTQSQLRFLPERHSDFAVAVFGEEWGFVGCVALVTLFCLFLLSIFSTAAQAKDRFGSMLVVGVFFYFFWQILI
NMGMVIGIMPVVGIPLPFISYGGSATVVNFTLLGIVLNVSMRRFMFKG
>Mature_368_residues
MDKSLFSYINWGLLACMLLLYLVGVGNLYSASGTRVETGLAFNSFYQRQIIWGLCGLACMLLAMTFDYRQLRNLAWPFFF
LTMLLLLLVPIAGKTVYGAKRWLSLGFMSVQPSELAKLSVLVLAARLLARDGRPLGWKDFISIAFICLLPCALIVVQPDL
GTTMLILLILAGMILFHGLKGYVLKTCLLAVPCFGAFMWLVGMHDYQRQRILTFLDPTTDPRGTGYHIIQSRIAIGSGEL
WGKGFKEGTQSQLRFLPERHSDFAVAVFGEEWGFVGCVALVTLFCLFLLSIFSTAAQAKDRFGSMLVVGVFFYFFWQILI
NMGMVIGIMPVVGIPLPFISYGGSATVVNFTLLGIVLNVSMRRFMFKG

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=340, Percent_Identity=40.2941176470588, Blast_Score=228, Evalue=4e-61,
Organism=Escherichia coli, GI1786277, Length=286, Percent_Identity=34.965034965035, Blast_Score=161, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40976; Mature: 40976

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKSLFSYINWGLLACMLLLYLVGVGNLYSASGTRVETGLAFNSFYQRQIIWGLCGLACM
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHH
LLAMTFDYRQLRNLAWPFFFLTMLLLLLVPIAGKTVYGAKRWLSLGFMSVQPSELAKLSV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
LVLAARLLARDGRPLGWKDFISIAFICLLPCALIVVQPDLGTTMLILLILAGMILFHGLK
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCHH
GYVLKTCLLAVPCFGAFMWLVGMHDYQRQRILTFLDPTTDPRGTGYHIIQSRIAIGSGEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCC
WGKGFKEGTQSQLRFLPERHSDFAVAVFGEEWGFVGCVALVTLFCLFLLSIFSTAAQAKD
CCCCHHCCHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFGSMLVVGVFFYFFWQILINMGMVIGIMPVVGIPLPFISYGGSATVVNFTLLGIVLNVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHH
MRRFMFKG
HHHHHCCC
>Mature Secondary Structure
MDKSLFSYINWGLLACMLLLYLVGVGNLYSASGTRVETGLAFNSFYQRQIIWGLCGLACM
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHH
LLAMTFDYRQLRNLAWPFFFLTMLLLLLVPIAGKTVYGAKRWLSLGFMSVQPSELAKLSV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHH
LVLAARLLARDGRPLGWKDFISIAFICLLPCALIVVQPDLGTTMLILLILAGMILFHGLK
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCHH
GYVLKTCLLAVPCFGAFMWLVGMHDYQRQRILTFLDPTTDPRGTGYHIIQSRIAIGSGEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCC
WGKGFKEGTQSQLRFLPERHSDFAVAVFGEEWGFVGCVALVTLFCLFLLSIFSTAAQAKD
CCCCHHCCHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFGSMLVVGVFFYFFWQILINMGMVIGIMPVVGIPLPFISYGGSATVVNFTLLGIVLNVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHH
MRRFMFKG
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]