Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 21909845

GI number: 21909845

Start: 350940

End: 351638

Strand: Direct

Name: fabG [H]

Synonym: SpyM3_0309

Alternate gene names: 21909845

Gene position: 350940-351638 (Clockwise)

Preceding gene: 21909844

Following gene: 21909846

Centisome position: 18.47

GC content: 44.21

Gene sequence:

>699_bases
ATGACTAAAGTTGTTTTAGTGACGGGCTGTGCTAGTGGGATTGGTTATGCACAGGCCCGCTATTTTTTGAGACAAGGGCA
TCACGTATATGGTGTGGATAAGTCGGATAAACCGGACTTAAACGGTAACTTTCACTTTATCAAATTGGATTTATCCTCTG
AGTTATCCCCACTATTTAAAGTGGTCCCCAGTGTTGATATTTTGTGTAATACTGCAGGGATTTTAGATGCCTACAAGCCA
CTTTTAGACGTCAGTGATGAAGAAGTGGAACACCTATTTGATATTAATTTTTTTGCGACGGTGAAGTTAACACGTCATTA
TCTTAGACGTATGGTGGAAAAGCAGTCAGGTGTTATCATCAATATGTGCTCAATAGCAAGTTTTATAGCAGGTGGCGGTG
GTGTTGCCTATACGAGTTCTAAGCATGCCCTTGCGGGCTTCACGCGCCAGCTGGCTTTGGATTACGCCAAAGATCAGATT
CACATCTTTGGTATAGCACCAGGTGCTGTCAAAACCGCTATGACGGCTAGCGACTTTGAGCCTGGTGGCTTAGCAGACTG
GGTAGCTCGTGAGACGCCAATTGGGCGTTGGACTGAACCAGATGAAGTTGCTGAATTAACGGGATTTCTTGCGTCAGGAA
AAGCGAGATCAATGCAAGGTGAAATTGTCAAAATTGACGGTGGCTGGACTTTGAAATGA

Upstream 100 bases:

>100_bases
ACGCCTTATTTTCTGATTCATGTTACTGGTGCAGGTGAAGGTTTTTCCATGTGGGCACCGACACCATGTGATGTGTTAGC
AGAGGATTGGATCGAGGTCA

Downstream 100 bases:

>100_bases
TCACATGCCTTAGCTTGAGCTGGCGCAGTAAGCCCTAGAGGTGTGATGAGTCAAACAGTCAAAGGAGATGAACAAATGAA
ATTAGCGGTTTTGGGAACAG

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MTKVVLVTGCASGIGYAQARYFLRQGHHVYGVDKSDKPDLNGNFHFIKLDLSSELSPLFKVVPSVDILCNTAGILDAYKP
LLDVSDEEVEHLFDINFFATVKLTRHYLRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQI
HIFGIAPGAVKTAMTASDFEPGGLADWVARETPIGRWTEPDEVAELTGFLASGKARSMQGEIVKIDGGWTLK

Sequences:

>Translated_232_residues
MTKVVLVTGCASGIGYAQARYFLRQGHHVYGVDKSDKPDLNGNFHFIKLDLSSELSPLFKVVPSVDILCNTAGILDAYKP
LLDVSDEEVEHLFDINFFATVKLTRHYLRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQI
HIFGIAPGAVKTAMTASDFEPGGLADWVARETPIGRWTEPDEVAELTGFLASGKARSMQGEIVKIDGGWTLK
>Mature_231_residues
TKVVLVTGCASGIGYAQARYFLRQGHHVYGVDKSDKPDLNGNFHFIKLDLSSELSPLFKVVPSVDILCNTAGILDAYKPL
LDVSDEEVEHLFDINFFATVKLTRHYLRRMVEKQSGVIINMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQIH
IFGIAPGAVKTAMTASDFEPGGLADWVARETPIGRWTEPDEVAELTGFLASGKARSMQGEIVKIDGGWTLK

Specific function: Reduces cyclopentanol to cyclopentanone. The enzyme also shows considerable activity toward cyclohexanol [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=29.2181069958848, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI32483357, Length=241, Percent_Identity=28.6307053941909, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI66933014, Length=241, Percent_Identity=28.2157676348548, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=28.0632411067194, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI7705925, Length=235, Percent_Identity=25.9574468085106, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=26.3779527559055, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=26.6393442622951, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=31.2, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI87082160, Length=245, Percent_Identity=28.9795918367347, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1790717, Length=241, Percent_Identity=27.8008298755187, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=31.1203319502075, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=27.8884462151394, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=27.0491803278689, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787820, Length=191, Percent_Identity=31.413612565445, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1786701, Length=185, Percent_Identity=32.4324324324324, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1789378, Length=243, Percent_Identity=27.5720164609054, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786812, Length=243, Percent_Identity=26.7489711934156, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=29.8755186721992, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI2367365, Length=234, Percent_Identity=28.2051282051282, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=246, Percent_Identity=29.2682926829268, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=30.2788844621514, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=251, Percent_Identity=30.6772908366534, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=242, Percent_Identity=26.8595041322314, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=28.6290322580645, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=25.8196721311475, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=27.9835390946502, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=241, Percent_Identity=26.5560165975104, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=30.0751879699248, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=27.0992366412214, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=28.735632183908, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=260, Percent_Identity=27.3076923076923, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=190, Percent_Identity=30, Blast_Score=76, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322861, Length=167, Percent_Identity=31.1377245508982, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322226, Length=211, Percent_Identity=29.3838862559242, Blast_Score=62, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=29.9180327868852, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24643142, Length=239, Percent_Identity=30.9623430962343, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI23397609, Length=242, Percent_Identity=30.1652892561983, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=27.3469387755102, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=30.1960784313725, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21358495, Length=225, Percent_Identity=27.1111111111111, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281364892, Length=192, Percent_Identity=28.6458333333333, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=26, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.163 [H]

Molecular weight: Translated: 25228; Mature: 25097

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVVLVTGCASGIGYAQARYFLRQGHHVYGVDKSDKPDLNGNFHFIKLDLSSELSPLFK
CCEEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHH
VVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINFFATVKLTRHYLRRMVEKQSGVII
HHCCHHEEECCHHHHHHHHHHHCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCEEE
NMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQIHIFGIAPGAVKTAMTASDFE
EHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHCCCCCC
PGGLADWVARETPIGRWTEPDEVAELTGFLASGKARSMQGEIVKIDGGWTLK
CCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCEECC
>Mature Secondary Structure 
TKVVLVTGCASGIGYAQARYFLRQGHHVYGVDKSDKPDLNGNFHFIKLDLSSELSPLFK
CEEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHH
VVPSVDILCNTAGILDAYKPLLDVSDEEVEHLFDINFFATVKLTRHYLRRMVEKQSGVII
HHCCHHEEECCHHHHHHHHHHHCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCEEE
NMCSIASFIAGGGGVAYTSSKHALAGFTRQLALDYAKDQIHIFGIAPGAVKTAMTASDFE
EHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHCCCCCC
PGGLADWVARETPIGRWTEPDEVAELTGFLASGKARSMQGEIVKIDGGWTLK
CCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12406764 [H]