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The map label for this gene is speG [H]

Identifier: 21909691

GI number: 21909691

Start: 183529

End: 184233

Strand: Direct

Name: speG [H]

Synonym: SpyM3_0155

Alternate gene names: 21909691

Gene position: 183529-184233 (Clockwise)

Preceding gene: 21909689

Following gene: 21909692

Centisome position: 9.66

GC content: 27.8

Gene sequence:

>705_bases
ATGAAAACAAACATTTTGACAATTATCATATTATCATGTGTTTTTAGCTATGGAAGTCAATTAGCTTATGCAGATGAAAA
TTTAAAAGATTTAAAAAGAAGTTTAAGGTTTGCCTATAATATTACCCCATGCGATTATGAAAATGTAGAAATTGCATTTG
TTACTACAAATAGCATACATATTAATACTAAACAAAAAAGATCGGAATGTATTCTTTATGTTGATTCTATTGTATCTTTA
GGCATTACTGATCAGTTTATAAAAGGGGATAAGGTCGATGTTTTTGGTCTCCCTTATAATTTTTCTCCACCTTATGTAGA
TAATATTTATGGTGGTATTGTAAAACATTCGAATCAAGGAAATAAATCATTACAGTTTGTAGGAATTTTAAATCAAGATG
GGAAAGAAACTTATTTGCCCTCTGAGGTTGTTCGCATAAAAAAGAAACAGTTTACTTTACAGGAATTTGATCTTAAAATA
AGAAAATTTCTAATGGAAAAATACAATATCTATGATTCGGAATCGCGTTATACATCGGGGAGCCTTTTCCTTGCTACTAA
AGATAGTAAACATTATGAAGTTGATTTATTTAATAAGGATGATAAGCTTTTAAGTCGAGACAGTTTCTTTAAAAGGTATA
AAGATAATAAGATTTTTAATAGTGAAGAAATTAGTCATTTTGATATCTACTTAAAAACGTACTAG

Upstream 100 bases:

>100_bases
CTAAAGTAATCTCTTCCTTCTATAGTGTCATCAGTTGTTGAAACCGATTGATATTTTTATTTAGGTTAAGAGGTGTAAAA
CAGGACATAAAAAGTTTTAA

Downstream 100 bases:

>100_bases
TGCTATTCTCCCCTCCCCTTTTTGCTTTTTAAGTATTCAAATGATTGCCATTTTTAGATAATGAGAGTAAGTAATGTTAA
GAAGATAGCATGAGAAAGTA

Product: pyrogenic exotoxin G precursor

Products: NA

Alternate protein names: Pyrogenic exotoxin G; SPE G [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MKTNILTIIILSCVFSYGSQLAYADENLKDLKRSLRFAYNITPCDYENVEIAFVTTNSIHINTKQKRSECILYVDSIVSL
GITDQFIKGDKVDVFGLPYNFSPPYVDNIYGGIVKHSNQGNKSLQFVGILNQDGKETYLPSEVVRIKKKQFTLQEFDLKI
RKFLMEKYNIYDSESRYTSGSLFLATKDSKHYEVDLFNKDDKLLSRDSFFKRYKDNKIFNSEEISHFDIYLKTY

Sequences:

>Translated_234_residues
MKTNILTIIILSCVFSYGSQLAYADENLKDLKRSLRFAYNITPCDYENVEIAFVTTNSIHINTKQKRSECILYVDSIVSL
GITDQFIKGDKVDVFGLPYNFSPPYVDNIYGGIVKHSNQGNKSLQFVGILNQDGKETYLPSEVVRIKKKQFTLQEFDLKI
RKFLMEKYNIYDSESRYTSGSLFLATKDSKHYEVDLFNKDDKLLSRDSFFKRYKDNKIFNSEEISHFDIYLKTY
>Mature_234_residues
MKTNILTIIILSCVFSYGSQLAYADENLKDLKRSLRFAYNITPCDYENVEIAFVTTNSIHINTKQKRSECILYVDSIVSL
GITDQFIKGDKVDVFGLPYNFSPPYVDNIYGGIVKHSNQGNKSLQFVGILNQDGKETYLPSEVVRIKKKQFTLQEFDLKI
RKFLMEKYNIYDSESRYTSGSLFLATKDSKHYEVDLFNKDDKLLSRDSFFKRYKDNKIFNSEEISHFDIYLKTY

Specific function: Mitogenic for human peripheral blood lymphocytes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the staphylococcal/streptococcal toxin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008992
- InterPro:   IPR006126
- InterPro:   IPR006173
- InterPro:   IPR016091
- InterPro:   IPR013307
- InterPro:   IPR006123 [H]

Pfam domain/function: PF02876 Stap_Strp_tox_C; PF01123 Stap_Strp_toxin [H]

EC number: NA

Molecular weight: Translated: 27282; Mature: 27282

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS00278 STAPH_STREP_TOXIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTNILTIIILSCVFSYGSQLAYADENLKDLKRSLRFAYNITPCDYENVEIAFVTTNSIH
CCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHEEEECCCCCCCCEEEEEEEECEEE
INTKQKRSECILYVDSIVSLGITDQFIKGDKVDVFGLPYNFSPPYVDNIYGGIVKHSNQG
EECCCCCCCEEEEEEHHHHCCCCHHHHCCCCEEEEECCCCCCCCCHHHHHHHHEEECCCC
NKSLQFVGILNQDGKETYLPSEVVRIKKKQFTLQEFDLKIRKFLMEKYNIYDSESRYTSG
CCEEEEEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
SLFLATKDSKHYEVDLFNKDDKLLSRDSFFKRYKDNKIFNSEEISHFDIYLKTY
EEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEC
>Mature Secondary Structure
MKTNILTIIILSCVFSYGSQLAYADENLKDLKRSLRFAYNITPCDYENVEIAFVTTNSIH
CCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHEEEECCCCCCCCEEEEEEEECEEE
INTKQKRSECILYVDSIVSLGITDQFIKGDKVDVFGLPYNFSPPYVDNIYGGIVKHSNQG
EECCCCCCCEEEEEEHHHHCCCCHHHHCCCCEEEEECCCCCCCCCHHHHHHHHEEECCCC
NKSLQFVGILNQDGKETYLPSEVVRIKKKQFTLQEFDLKIRKFLMEKYNIYDSESRYTSG
CCEEEEEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
SLFLATKDSKHYEVDLFNKDDKLLSRDSFFKRYKDNKIFNSEEISHFDIYLKTY
EEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9874566; 11296296 [H]