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The map label for this gene is tadA [H]

Identifier: 21909689

GI number: 21909689

Start: 180767

End: 181282

Strand: Direct

Name: tadA [H]

Synonym: SpyM3_0153

Alternate gene names: 21909689

Gene position: 180767-181282 (Clockwise)

Preceding gene: 21909688

Following gene: 21909691

Centisome position: 9.51

GC content: 45.35

Gene sequence:

>516_bases
ATGCCATATAGTTTAGAAGAGCAAACTTATTTCATGCAAGAGGCTTTAAAAGAAGCCGAAAAATCCTTACAGAAAGCTGA
AATCCCCATTGGCTGTGTCATTGTCAAGGATGGTGAGATTATTGGTCGTGGGCACAATGCGCGTGAAGAGAGTAACCAAG
CCATTATGCACGCTGAAATGATGGCCATTAACGAGGCTAACGCTCATGAAGGCAACTGGCGTTTATTAGACACCACACTC
TTTGTGACCATCGAGCCTTGTGTGATGTGTAGTGGTGCCATTGGGCTAGCAAGGATTCCGCATGTTATTTATGGAGCCAG
CAATCAAAAATTTGGTGGAGCAGACAGCCTTTACCAGATTTTGACAGATGAGCGCTTAAACCATCGCGTGCAAGTTGAAC
GAGGCCTGCTAGCAGCAGACTGTGCTAACATCATGCAAACCTTTTTCCGCCAAGGGCGAGAGCGCAAAAAAATAGCTAAG
CATTTGATCAAGGAACAGTCAGATCCCTTTGACTAG

Upstream 100 bases:

>100_bases
ACTTGGAAGTGTTGAGGCAAGAAACACAAGCCTATGCAGGTAATATTCCTGTTGACCTTGCCTTACCACACAAATCTTGG
AACTTGGGGAGTCTTTCTTG

Downstream 100 bases:

>100_bases
AGTTTTAAGGAGTTTGTTATCACATGCATTTTTGGTGAAGGGTAGCCTGTCAAAATACTGAGTGAAACGTTAGACCATTT
TTCCAATGGTTGTTAGATTC

Product: putative cytidine/deoxycytidylate deaminase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MPYSLEEQTYFMQEALKEAEKSLQKAEIPIGCVIVKDGEIIGRGHNAREESNQAIMHAEMMAINEANAHEGNWRLLDTTL
FVTIEPCVMCSGAIGLARIPHVIYGASNQKFGGADSLYQILTDERLNHRVQVERGLLAADCANIMQTFFRQGRERKKIAK
HLIKEQSDPFD

Sequences:

>Translated_171_residues
MPYSLEEQTYFMQEALKEAEKSLQKAEIPIGCVIVKDGEIIGRGHNAREESNQAIMHAEMMAINEANAHEGNWRLLDTTL
FVTIEPCVMCSGAIGLARIPHVIYGASNQKFGGADSLYQILTDERLNHRVQVERGLLAADCANIMQTFFRQGRERKKIAK
HLIKEQSDPFD
>Mature_170_residues
PYSLEEQTYFMQEALKEAEKSLQKAEIPIGCVIVKDGEIIGRGHNAREESNQAIMHAEMMAINEANAHEGNWRLLDTTLF
VTIEPCVMCSGAIGLARIPHVIYGASNQKFGGADSLYQILTDERLNHRVQVERGLLAADCANIMQTFFRQGRERKKIAKH
LIKEQSDPFD

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=156, Percent_Identity=33.974358974359, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI145693172, Length=151, Percent_Identity=40.3973509933775, Blast_Score=128, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17541138, Length=148, Percent_Identity=35.1351351351351, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17554608, Length=100, Percent_Identity=39, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6322425, Length=118, Percent_Identity=32.2033898305085, Blast_Score=77, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325319, Length=96, Percent_Identity=37.5, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=32.1917808219178, Blast_Score=87, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 19261; Mature: 19130

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYSLEEQTYFMQEALKEAEKSLQKAEIPIGCVIVKDGEIIGRGHNAREESNQAIMHAEM
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCEEEECCCCCCHHHHHHHHHHHH
MAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHVIYGASNQKFGGADSLYQI
HHHCCCCCCCCCEEEEEEEEEEEECHHHHHCCCHHHHHHCHHEECCCCCCCCCHHHHHHH
LTDERLNHRVQVERGLLAADCANIMQTFFRQGRERKKIAKHLIKEQSDPFD
HHHHHHCCHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PYSLEEQTYFMQEALKEAEKSLQKAEIPIGCVIVKDGEIIGRGHNAREESNQAIMHAEM
CCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCEEEECCCCCCHHHHHHHHHHHH
MAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHVIYGASNQKFGGADSLYQI
HHHCCCCCCCCCEEEEEEEEEEEECHHHHHCCCHHHHHHCHHEECCCCCCCCCHHHHHHH
LTDERLNHRVQVERGLLAADCANIMQTFFRQGRERKKIAKHLIKEQSDPFD
HHHHHHCCHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]