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The map label for this gene is mppA [H]

Identifier: 218929431

GI number: 218929431

Start: 2632546

End: 2634162

Strand: Reverse

Name: mppA [H]

Synonym: YPO2339

Alternate gene names: 218929431

Gene position: 2634162-2632546 (Counterclockwise)

Preceding gene: 218929433

Following gene: 218929430

Centisome position: 56.6

GC content: 43.54

Gene sequence:

>1617_bases
ATGCACTATTTTCGTTATGCATTATGTGCCGTAGTAGTCGGTTCAGTACTGGGAGCGGCAAATGCGGCTGAGGTCCCTCC
TGGAACGGTATTGGCTGAAAAACAAGAAATTGTTCGGCATATTAAAGATGAGCCAGCATCGCTGGATCCAATGAAAGCCG
TTGGGTTGATAGAGGCTCAGGTGGTACGGGATCTGTTTGAAGGTCTGGTTAATCAAGATGCCCATGGGCAGCCTATTCCC
GGTGTCGCATTGAGCTGGAAAACAGCAGATAACCAAACCTATATCTTCACCTTACGTAAAGATGCGAAATGGTCCAATGG
TGAACCTGTCACTGCGCAAGATTTTGTCTACAGCTGGCGTCGCTTGGTCGATCCTAAAAGTTTGTCTCCGTTTGCCTGGT
TTGCAGAACTGGCCGGAATGGAGAATGCGCAACAGATTATTTCCGGTCAAATGCCACCGGAAGCACTGGGTGTGAGCGCG
ATTGATCATTACACCCTGAAAGTTAAACTCAGTAAACCCGTTCCTTATTTCCCAAGCCTGACCGCAAATTTCAGTTTATT
CCCCGTGCCACAATCTGTTATTGAAAAATATGGTAACAATTGGACTAAGGTCGGTAATTTGGTCGGTAACGGTGCATTTA
AATTACAAGACCGAGTCGTTAATGAAAAGTTAGTGTTTGTTCCTAATGAGTATTATTGGGATCATGGACGCACTGTTCTG
ACCAAAGTAACCTTTGTTCCCATTAGCCAAGAAGCGAATGCTACCAAACGCTATCTGGCAGGGGATATTGATATTACGGA
GTCATTCCCGAAGAATTTGTATCAAAAACTGTTAAAGGATATTCCTGATCAAGTTTATACCCCGGATCAGTTAGGGACTT
ATTATTATGCTTTTAATACTCAACGCGCGCCGACCAATGATGTTCGGGTACGTAAAGCATTATCTTATGCGATAGATCGA
AAAATTATTGCTGAGAAGGTATTAGGTACCGGAGAAAAACCCGCTTATCACTTTACCCCAGATGTCACCGCAGGCTATGA
ACCGGCGGCGAGCTTATTGCAGCAACAGAGCCAAGAGGAGTTAAATGCTCAAGCCAAATCTTTGCTTCATGCCGCGGGCT
ATGGCCCAGATAAACCGTTAACACTGACCTTGCTGTATAACACCTCCGATAATAACCAGAAGTTGGCTATTGCTATCGCA
TCGATGTGGAAAAAGACCTTGGGAATCGATGTGAAAATGGTCAATCAAGAATGGAAAACCTATATTGATAGCCGTAATAC
CGGTAATTTTGATGTCGTGCGAGCATCATGGATAGGTGATTATAATGAGCCATCAACTTTTCTGTCGTTATTAACATCCA
GGCATAGCGGGAATATTGCCAAATTCAATAATGCTGATTACGATCGTTTACTGGCCGATGCGGGTAAGCAGACAAACGCT
AAAGCACTGAGTGCTGATTATAATAAAGCCGAGCAAATTATTGCGGAACAGGTCCCTATCGCACCGATATATCAATTTAC
TAATGGCCGTTTAATTAAATCCTGGGTGAAAGGTTACCCGATAACCAATCCAGAAGATGTTGCTTACAGTCAGAACTTAT
ATATTATTAAGCACTGA

Upstream 100 bases:

>100_bases
GACTGGCCTGAGTATTGCCTACGTGGTGTGTTGGCCAGCAGGCTAGGTATTGAGAATCTACTTTCGCTGATATGGAACAA
CAACGATAAGGTTATCGATT

Downstream 100 bases:

>100_bases
TAGTTATGGGCTTATTGTTTTTAACTAATTAACAGAGGCGGATTTTAAATCCGCCTTTGCATTTATTCTTGTCCTTTATT
CATAATTATTTTCGCGTCTC

Product: putative periplasmic murein peptide-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MHYFRYALCAVVVGSVLGAANAAEVPPGTVLAEKQEIVRHIKDEPASLDPMKAVGLIEAQVVRDLFEGLVNQDAHGQPIP
GVALSWKTADNQTYIFTLRKDAKWSNGEPVTAQDFVYSWRRLVDPKSLSPFAWFAELAGMENAQQIISGQMPPEALGVSA
IDHYTLKVKLSKPVPYFPSLTANFSLFPVPQSVIEKYGNNWTKVGNLVGNGAFKLQDRVVNEKLVFVPNEYYWDHGRTVL
TKVTFVPISQEANATKRYLAGDIDITESFPKNLYQKLLKDIPDQVYTPDQLGTYYYAFNTQRAPTNDVRVRKALSYAIDR
KIIAEKVLGTGEKPAYHFTPDVTAGYEPAASLLQQQSQEELNAQAKSLLHAAGYGPDKPLTLTLLYNTSDNNQKLAIAIA
SMWKKTLGIDVKMVNQEWKTYIDSRNTGNFDVVRASWIGDYNEPSTFLSLLTSRHSGNIAKFNNADYDRLLADAGKQTNA
KALSADYNKAEQIIAEQVPIAPIYQFTNGRLIKSWVKGYPITNPEDVAYSQNLYIIKH

Sequences:

>Translated_538_residues
MHYFRYALCAVVVGSVLGAANAAEVPPGTVLAEKQEIVRHIKDEPASLDPMKAVGLIEAQVVRDLFEGLVNQDAHGQPIP
GVALSWKTADNQTYIFTLRKDAKWSNGEPVTAQDFVYSWRRLVDPKSLSPFAWFAELAGMENAQQIISGQMPPEALGVSA
IDHYTLKVKLSKPVPYFPSLTANFSLFPVPQSVIEKYGNNWTKVGNLVGNGAFKLQDRVVNEKLVFVPNEYYWDHGRTVL
TKVTFVPISQEANATKRYLAGDIDITESFPKNLYQKLLKDIPDQVYTPDQLGTYYYAFNTQRAPTNDVRVRKALSYAIDR
KIIAEKVLGTGEKPAYHFTPDVTAGYEPAASLLQQQSQEELNAQAKSLLHAAGYGPDKPLTLTLLYNTSDNNQKLAIAIA
SMWKKTLGIDVKMVNQEWKTYIDSRNTGNFDVVRASWIGDYNEPSTFLSLLTSRHSGNIAKFNNADYDRLLADAGKQTNA
KALSADYNKAEQIIAEQVPIAPIYQFTNGRLIKSWVKGYPITNPEDVAYSQNLYIIKH
>Mature_538_residues
MHYFRYALCAVVVGSVLGAANAAEVPPGTVLAEKQEIVRHIKDEPASLDPMKAVGLIEAQVVRDLFEGLVNQDAHGQPIP
GVALSWKTADNQTYIFTLRKDAKWSNGEPVTAQDFVYSWRRLVDPKSLSPFAWFAELAGMENAQQIISGQMPPEALGVSA
IDHYTLKVKLSKPVPYFPSLTANFSLFPVPQSVIEKYGNNWTKVGNLVGNGAFKLQDRVVNEKLVFVPNEYYWDHGRTVL
TKVTFVPISQEANATKRYLAGDIDITESFPKNLYQKLLKDIPDQVYTPDQLGTYYYAFNTQRAPTNDVRVRKALSYAIDR
KIIAEKVLGTGEKPAYHFTPDVTAGYEPAASLLQQQSQEELNAQAKSLLHAAGYGPDKPLTLTLLYNTSDNNQKLAIAIA
SMWKKTLGIDVKMVNQEWKTYIDSRNTGNFDVVRASWIGDYNEPSTFLSLLTSRHSGNIAKFNNADYDRLLADAGKQTNA
KALSADYNKAEQIIAEQVPIAPIYQFTNGRLIKSWVKGYPITNPEDVAYSQNLYIIKH

Specific function: Essential for the uptake of the murein peptide L-alanyl- gamma-D-glutamyl-meso-diaminopimelate. Also transports some alpha- linked peptides such as Pro-Phe-Lys with low affinity. The transport is effected by the oligopeptide permease system [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI87081878, Length=537, Percent_Identity=70.5772811918063, Blast_Score=803, Evalue=0.0,
Organism=Escherichia coli, GI1787495, Length=536, Percent_Identity=49.0671641791045, Blast_Score=515, Evalue=1e-147,
Organism=Escherichia coli, GI1789397, Length=518, Percent_Identity=42.4710424710425, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI1787762, Length=539, Percent_Identity=26.3450834879406, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1789887, Length=406, Percent_Identity=29.064039408867, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1789966, Length=488, Percent_Identity=24.3852459016393, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1787551, Length=531, Percent_Identity=22.5988700564972, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787052, Length=525, Percent_Identity=21.3333333333333, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60026; Mature: 60026

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYFRYALCAVVVGSVLGAANAAEVPPGTVLAEKQEIVRHIKDEPASLDPMKAVGLIEAQ
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
VVRDLFEGLVNQDAHGQPIPGVALSWKTADNQTYIFTLRKDAKWSNGEPVTAQDFVYSWR
HHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHH
RLVDPKSLSPFAWFAELAGMENAQQIISGQMPPEALGVSAIDHYTLKVKLSKPVPYFPSL
HHCCCCCCCHHHHHHHHHCCCHHHHHHCCCCCHHHHCCCEEEEEEEEEEECCCCCCCCCC
TANFSLFPVPQSVIEKYGNNWTKVGNLVGNGAFKLQDRVVNEKLVFVPNEYYWDHGRTVL
CCCCEEECCCHHHHHHHCCCHHHHHHHHCCCCEEEHHHHCCCEEEEECCCEEECCCCEEE
TKVTFVPISQEANATKRYLAGDIDITESFPKNLYQKLLKDIPDQVYTPDQLGTYYYAFNT
EEEEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHCCCCHHHCCEEEEEEC
QRAPTNDVRVRKALSYAIDRKIIAEKVLGTGEKPAYHFTPDVTAGYEPAASLLQQQSQEE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHH
LNAQAKSLLHAAGYGPDKPLTLTLLYNTSDNNQKLAIAIASMWKKTLGIDVKMVNQEWKT
HHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHHHCCEEEEECHHHHH
YIDSRNTGNFDVVRASWIGDYNEPSTFLSLLTSRHSGNIAKFNNADYDRLLADAGKQTNA
HHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHCCCCCCC
KALSADYNKAEQIIAEQVPIAPIYQFTNGRLIKSWVKGYPITNPEDVAYSQNLYIIKH
HHHHCCHHHHHHHHHHHCCCCCEEECCCCCHHHHHHCCCCCCCCHHCEECCCEEEEEC
>Mature Secondary Structure
MHYFRYALCAVVVGSVLGAANAAEVPPGTVLAEKQEIVRHIKDEPASLDPMKAVGLIEAQ
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
VVRDLFEGLVNQDAHGQPIPGVALSWKTADNQTYIFTLRKDAKWSNGEPVTAQDFVYSWR
HHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHH
RLVDPKSLSPFAWFAELAGMENAQQIISGQMPPEALGVSAIDHYTLKVKLSKPVPYFPSL
HHCCCCCCCHHHHHHHHHCCCHHHHHHCCCCCHHHHCCCEEEEEEEEEEECCCCCCCCCC
TANFSLFPVPQSVIEKYGNNWTKVGNLVGNGAFKLQDRVVNEKLVFVPNEYYWDHGRTVL
CCCCEEECCCHHHHHHHCCCHHHHHHHHCCCCEEEHHHHCCCEEEEECCCEEECCCCEEE
TKVTFVPISQEANATKRYLAGDIDITESFPKNLYQKLLKDIPDQVYTPDQLGTYYYAFNT
EEEEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHCCCCHHHCCEEEEEEC
QRAPTNDVRVRKALSYAIDRKIIAEKVLGTGEKPAYHFTPDVTAGYEPAASLLQQQSQEE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHH
LNAQAKSLLHAAGYGPDKPLTLTLLYNTSDNNQKLAIAIASMWKKTLGIDVKMVNQEWKT
HHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHHHCCEEEEECHHHHH
YIDSRNTGNFDVVRASWIGDYNEPSTFLSLLTSRHSGNIAKFNNADYDRLLADAGKQTNA
HHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCEEECCCCCHHHHHHHCCCCCCC
KALSADYNKAEQIIAEQVPIAPIYQFTNGRLIKSWVKGYPITNPEDVAYSQNLYIIKH
HHHHCCHHHHHHHHHHHCCCCCEEECCCCCHHHHHHCCCCCCCCHHCEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9495761; 9097039; 9278503 [H]