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The map label for this gene is pntB [H]

Identifier: 218929394

GI number: 218929394

Start: 2588577

End: 2589971

Strand: Reverse

Name: pntB [H]

Synonym: YPO2302

Alternate gene names: 218929394

Gene position: 2589971-2588577 (Counterclockwise)

Preceding gene: 218929395

Following gene: 218929390

Centisome position: 55.65

GC content: 48.1

Gene sequence:

>1395_bases
ATGTCTAGTGGTCTCGTTACAGCTGCGTACATAGTTGCTGCGATCTTATTTATCTTCAGTTTGGCTGGGCTGTCGCGCCA
TGAAACATCCAGACAAGGCAATTCTTTCGGTGTGGCCGGTATGGCCATCGCGTTAATTGCGACTATTCTGGGGCCAGATT
CAAGTAATGTCGCTTGGATAATCATTGCGATGGTCATCGGTGGTGCGATCGGTATCTATCTGGCGAAGAAAGTCGAAATG
ACTGAAATGCCAGAACTGGTAGCGATTCTGCATAGCTTCGTTGGTCTGGCCGCGGTTCTGGTTGGTTTTAACAGCTATCT
GGATCATGGTTCGATGATGGATGCGGTGATGGAGAACATCCATCTGACCGAAGTCTTCCTCGGTATCTTTATCGGTGCGG
TGACATTTACCGGTTCTATTGTCGCCTTCGGTAAGTTACGTGGGGTTATCTCATCCAAGCCATTGATGTTACCGCAACGC
CATAAGCTGAATCTGGTGGCGTTGGTTGTTTCCTTCCTCTTGATGGTTACGTTCGTTAGAACGGAGAGTATTACCCTGCA
AGTGGTTGCGCTGCTATTGATGACCCTAATTGCGCTGGGCTTTGGTTGGCATCTGGTGGCTTCAATTGGCGGTGCAGACA
TGCCCGTTGTTGTTTCAATGCTGAACTCTTATTCTGGTTGGGCAGCAGCAGCAGCAGGCTTTATGCTGAGTAATGACCTG
TTGATTGTGACGGGTGCATTGGTCGGTTCTTCTGGTGCGATCCTGTCTTACATCATGTGTAAAGCGATGAACCGTTCATT
TATCAGTGTCATTGCCGGTGGTTTCGGTACTGATGGTTCTTCTACCGGCAATGCTGAAGAAATGGGCGAATATCGTGAAG
CCACAGCGGAAGACGTGGCAGAACAACTGAGAAATGCCAGTTCAGTTATTATCACACCAGGATATGGGATGGCGGTAGCG
CAGGCACAGTATCCGGTTGCTGAAATTACCGCAAAACTGCAAGCCCGTGGGATCAAAGTGCGTTTTGGTATCCATCCGGT
TGCCGGGCGTTTACCTGGTCACATGAACGTATTATTGGCTGAAGCTAAAGTACCTTATGACGTCGTACTGGAAATGGATG
AGATCAACGATGATTTCTCAAGTACGGATGTTGTCCTGGTGATTGGTGCCAACGATACCGTTAACCCCGCAGCTCTCGAA
GATCCACGTAGCCCGATTGCGGGTATGCCTGTACTCGAGGTGTGGAAAGCACACAGTGTCATCGCCTTTAAACGTTCAAT
GAATACCGGTTATGCGGGTGTCCAGAACCCATTGTTCTTTAAAGAAAATACTCAAATGTTGTTTGGTGATGCCAAAGACA
GCGTAGAAGCTATTTTACGTGCACTGAATAATTAA

Upstream 100 bases:

>100_bases
CATGCTGAAAATGTTCCGTAAAAACTAATGTTCCGTAAAAACCAAGCTACATAGAAATTAGCTGGTATAAAAATGTCATA
TAAAAACAAAGGGGTAACTG

Downstream 100 bases:

>100_bases
AATGTGTTGATTAACATCCATTGTATTGCTCAGGGCCACTTCGGTGGCCCTGAGGTTATTGACAAAGTGCCCGCGACGAG
AGAACAGGCAGATCGTAAAG

Product: pyridine nucleotide transhydrogenase

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Pyridine nucleotide transhydrogenase subunit beta [H]

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MSSGLVTAAYIVAAILFIFSLAGLSRHETSRQGNSFGVAGMAIALIATILGPDSSNVAWIIIAMVIGGAIGIYLAKKVEM
TEMPELVAILHSFVGLAAVLVGFNSYLDHGSMMDAVMENIHLTEVFLGIFIGAVTFTGSIVAFGKLRGVISSKPLMLPQR
HKLNLVALVVSFLLMVTFVRTESITLQVVALLLMTLIALGFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDL
LIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSTGNAEEMGEYREATAEDVAEQLRNASSVIITPGYGMAVA
QAQYPVAEITAKLQARGIKVRFGIHPVAGRLPGHMNVLLAEAKVPYDVVLEMDEINDDFSSTDVVLVIGANDTVNPAALE
DPRSPIAGMPVLEVWKAHSVIAFKRSMNTGYAGVQNPLFFKENTQMLFGDAKDSVEAILRALNN

Sequences:

>Translated_464_residues
MSSGLVTAAYIVAAILFIFSLAGLSRHETSRQGNSFGVAGMAIALIATILGPDSSNVAWIIIAMVIGGAIGIYLAKKVEM
TEMPELVAILHSFVGLAAVLVGFNSYLDHGSMMDAVMENIHLTEVFLGIFIGAVTFTGSIVAFGKLRGVISSKPLMLPQR
HKLNLVALVVSFLLMVTFVRTESITLQVVALLLMTLIALGFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDL
LIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSTGNAEEMGEYREATAEDVAEQLRNASSVIITPGYGMAVA
QAQYPVAEITAKLQARGIKVRFGIHPVAGRLPGHMNVLLAEAKVPYDVVLEMDEINDDFSSTDVVLVIGANDTVNPAALE
DPRSPIAGMPVLEVWKAHSVIAFKRSMNTGYAGVQNPLFFKENTQMLFGDAKDSVEAILRALNN
>Mature_463_residues
SSGLVTAAYIVAAILFIFSLAGLSRHETSRQGNSFGVAGMAIALIATILGPDSSNVAWIIIAMVIGGAIGIYLAKKVEMT
EMPELVAILHSFVGLAAVLVGFNSYLDHGSMMDAVMENIHLTEVFLGIFIGAVTFTGSIVAFGKLRGVISSKPLMLPQRH
KLNLVALVVSFLLMVTFVRTESITLQVVALLLMTLIALGFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDLL
IVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSTGNAEEMGEYREATAEDVAEQLRNASSVIITPGYGMAVAQ
AQYPVAEITAKLQARGIKVRFGIHPVAGRLPGHMNVLLAEAKVPYDVVLEMDEINDDFSSTDVVLVIGANDTVNPAALED
PRSPIAGMPVLEVWKAHSVIAFKRSMNTGYAGVQNPLFFKENTQMLFGDAKDSVEAILRALNN

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=453, Percent_Identity=51.4348785871965, Blast_Score=457, Evalue=1e-128,
Organism=Homo sapiens, GI122939153, Length=453, Percent_Identity=51.4348785871965, Blast_Score=457, Evalue=1e-128,
Organism=Escherichia coli, GI1787886, Length=462, Percent_Identity=85.9307359307359, Blast_Score=806, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17550456, Length=461, Percent_Identity=49.2407809110629, Blast_Score=426, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 49051; Mature: 48920

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HEEHHHCCCCCCCCCCCEEEECCCCEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SSGLVTAAYIVAAILFIFSLAGLSRHETSRQGNSFGVAGMAIALIATILGPDSSNVAWI
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHH
IIAMVIGGAIGIYLAKKVEMTEMPELVAILHSFVGLAAVLVGFNSYLDHGSMMDAVMENI
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
HLTEVFLGIFIGAVTFTGSIVAFGKLRGVISSKPLMLPQRHKLNLVALVVSFLLMVTFVR
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
TESITLQVVALLLMTLIALGFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCE
LIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSTGNAEEMGEYREATAEDVA
EEEEEHHHCCCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
EQLRNASSVIITPGYGMAVAQAQYPVAEITAKLQARGIKVRFGIHPVAGRLPGHMNVLLA
HHHCCCCCEEEECCCCCCHHHCCCCHHHHHHHHHHCCEEEEECCCHHCCCCCCCCEEEEE
EAKVPYDVVLEMDEINDDFSSTDVVLVIGANDTVNPAALEDPRSPIAGMPVLEVWKAHSV
CCCCCHHHEEEHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
IAFKRSMNTGYAGVQNPLFFKENTQMLFGDAKDSVEAILRALNN
HEEHHHCCCCCCCCCCCEEEECCCCEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]