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The map label for this gene is ttuB [H]

Identifier: 218929333

GI number: 218929333

Start: 2513188

End: 2514498

Strand: Direct

Name: ttuB [H]

Synonym: YPO2237

Alternate gene names: 218929333

Gene position: 2513188-2514498 (Clockwise)

Preceding gene: 218929329

Following gene: 218929334

Centisome position: 54.0

GC content: 47.44

Gene sequence:

>1311_bases
ATGTCTGAATCATCCACTGAATCTTTGTCGCAACCGACGCAGTTACAAGAAGAAAATAATGCCTACCGTAAAACGGTATG
GCATCTCTTGCCGCTACTGATGTTGTGTTACGTTCTCAACTACTTAGATCGGGTTAATGTTGGTTTTGCCAAGCTCCAAA
TGGCCGATGACTTGCAATTCTCGGATACGGTTTATGGCTTGGGGGCCGGTATGTTCTTTATCGGCTACTTTTTCCTGGAA
ATTCCCAGCAACCTGATACTGCATCGAGTTGGCGCAAGGTTGTGGATTGCGCGGATCATGATCACTTGGGGGATTATCTC
TGCCTGTATGGCATTTGTGACGACGCCGATGTCATTTTATGTGATGCGATTCTTACTCGGGGTTGCTGAAGCAGGTTTTT
TCCCAGGGATTATTCTTTATATTTCATATTGGTTTCCGTCTCACCGCCGTGGCCGCGTGTATGGATTATTCGTCATCTCG
GTACCGTTATCCGGCATCATAGGGGCACCACTGTCCGGCTGGATCATGCAGTATTTTAATGGTTTCCAAGGTTATGCTGG
CTGGCAATGGATGTTTATTCTGGAAGGTATTCCTTCCGTATTGGTGGGTATTTTAATCATTTATAAACTGAAAGATCGAA
TCACACATGCCACCTGGCTGACCGACAAAGAGAAAGATATCTTACAGACCAATATAGAGAACGAAGCTGCGCATTATGCA
CATAGCCGCCTGAGAGATGCCTTTTTGCAACCGCGAGTCTGGCTATTAACCCTTATTTATTTCTGTCTGATCAGCGGCTT
TTATACTATCGGTTTCTGGCTACCGACGTTGATTAGAGACAGTGGGGTAAAGGATATTTTAAGTATTGGTTTCTTAACCG
CCATTCCTTCTGCAGCGGCAGCGGTGACCATGATCGTCGTCTCGCGCAGTGCTGACCGTTTGCGGGAGCGACGCTGGCAT
CTGGCACTAACCGCGGTATTGGGTGCAGTGGGTATTATTCTCTCAACCTATTTTAGCGACAATATCGTTGTTGCGATGGT
GTGCTTAACCATTGGTGCTATGGGGGCGCTGAGTACGATACCGCTGTTCTGGAGCTTGCCCACCGCTTTCCTTGGCGGAA
GTGCGGCTGCAGCAGGTATCGCCTTTATTAACTCTTGGGGCAATCTGGGCGGATTTGTTGCGCCTTATATGATGGGATAC
CTGAAAGACTTGACCCAGAGTACCACGACCGGAATGTTGATCATTTCTACCACGCTATTTATTGGTGCCGCGCTGGTGTT
TTTGATCCCGGCCAAGGCAGTTAATCATTAA

Upstream 100 bases:

>100_bases
GTTTTGCTTAACGCCAGCCTTCGCAGTGCCAGGCAGTGTCGCCAAACCTTGTTCCCTACAGTTTGTTCCCTACAAAAATA
GTTAACAATGAGGTTTTATT

Downstream 100 bases:

>100_bases
CGACTAACGACGAACCAATAGACAGGAGGAGTCAGTGATGAACATTATGATAACGGGGGCTGCCGGTTTTCTGGGGCGTC
GATTGATTGACGGCTTACTG

Product: putative integral membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MSESSTESLSQPTQLQEENNAYRKTVWHLLPLLMLCYVLNYLDRVNVGFAKLQMADDLQFSDTVYGLGAGMFFIGYFFLE
IPSNLILHRVGARLWIARIMITWGIISACMAFVTTPMSFYVMRFLLGVAEAGFFPGIILYISYWFPSHRRGRVYGLFVIS
VPLSGIIGAPLSGWIMQYFNGFQGYAGWQWMFILEGIPSVLVGILIIYKLKDRITHATWLTDKEKDILQTNIENEAAHYA
HSRLRDAFLQPRVWLLTLIYFCLISGFYTIGFWLPTLIRDSGVKDILSIGFLTAIPSAAAAVTMIVVSRSADRLRERRWH
LALTAVLGAVGIILSTYFSDNIVVAMVCLTIGAMGALSTIPLFWSLPTAFLGGSAAAAGIAFINSWGNLGGFVAPYMMGY
LKDLTQSTTTGMLIISTTLFIGAALVFLIPAKAVNH

Sequences:

>Translated_436_residues
MSESSTESLSQPTQLQEENNAYRKTVWHLLPLLMLCYVLNYLDRVNVGFAKLQMADDLQFSDTVYGLGAGMFFIGYFFLE
IPSNLILHRVGARLWIARIMITWGIISACMAFVTTPMSFYVMRFLLGVAEAGFFPGIILYISYWFPSHRRGRVYGLFVIS
VPLSGIIGAPLSGWIMQYFNGFQGYAGWQWMFILEGIPSVLVGILIIYKLKDRITHATWLTDKEKDILQTNIENEAAHYA
HSRLRDAFLQPRVWLLTLIYFCLISGFYTIGFWLPTLIRDSGVKDILSIGFLTAIPSAAAAVTMIVVSRSADRLRERRWH
LALTAVLGAVGIILSTYFSDNIVVAMVCLTIGAMGALSTIPLFWSLPTAFLGGSAAAAGIAFINSWGNLGGFVAPYMMGY
LKDLTQSTTTGMLIISTTLFIGAALVFLIPAKAVNH
>Mature_435_residues
SESSTESLSQPTQLQEENNAYRKTVWHLLPLLMLCYVLNYLDRVNVGFAKLQMADDLQFSDTVYGLGAGMFFIGYFFLEI
PSNLILHRVGARLWIARIMITWGIISACMAFVTTPMSFYVMRFLLGVAEAGFFPGIILYISYWFPSHRRGRVYGLFVISV
PLSGIIGAPLSGWIMQYFNGFQGYAGWQWMFILEGIPSVLVGILIIYKLKDRITHATWLTDKEKDILQTNIENEAAHYAH
SRLRDAFLQPRVWLLTLIYFCLISGFYTIGFWLPTLIRDSGVKDILSIGFLTAIPSAAAAVTMIVVSRSADRLRERRWHL
ALTAVLGAVGIILSTYFSDNIVVAMVCLTIGAMGALSTIPLFWSLPTAFLGGSAAAAGIAFINSWGNLGGFVAPYMMGYL
KDLTQSTTTGMLIISTTLFIGAALVFLIPAKAVNH

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=390, Percent_Identity=22.5641025641026, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87082071, Length=406, Percent_Identity=39.1625615763547, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI2367379, Length=314, Percent_Identity=24.5222929936306, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1789515, Length=437, Percent_Identity=22.6544622425629, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87082320, Length=417, Percent_Identity=22.7817745803357, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789152, Length=451, Percent_Identity=23.059866962306, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI2367193, Length=255, Percent_Identity=24.7058823529412, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=200, Percent_Identity=28.5, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6319876, Length=357, Percent_Identity=25.2100840336134, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6323032, Length=280, Percent_Identity=24.2857142857143, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6322612, Length=269, Percent_Identity=26.0223048327138, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324410, Length=162, Percent_Identity=25.3086419753086, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321698, Length=414, Percent_Identity=22.463768115942, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319250, Length=323, Percent_Identity=25.6965944272446, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6321502, Length=322, Percent_Identity=23.6024844720497, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641682, Length=426, Percent_Identity=22.3004694835681, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20130167, Length=363, Percent_Identity=21.763085399449, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583789, Length=373, Percent_Identity=22.7882037533512, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48426; Mature: 48295

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESSTESLSQPTQLQEENNAYRKTVWHLLPLLMLCYVLNYLDRVNVGFAKLQMADDLQF
CCCCCCHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCH
SDTVYGLGAGMFFIGYFFLEIPSNLILHRVGARLWIARIMITWGIISACMAFVTTPMSFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VMRFLLGVAEAGFFPGIILYISYWFPSHRRGRVYGLFVISVPLSGIIGAPLSGWIMQYFN
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCHHHHHCCCHHHHHHHHHC
GFQGYAGWQWMFILEGIPSVLVGILIIYKLKDRITHATWLTDKEKDILQTNIENEAAHYA
CCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHH
HSRLRDAFLQPRVWLLTLIYFCLISGFYTIGFWLPTLIRDSGVKDILSIGFLTAIPSAAA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHH
AVTMIVVSRSADRLRERRWHLALTAVLGAVGIILSTYFSDNIVVAMVCLTIGAMGALSTI
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
PLFWSLPTAFLGGSAAAAGIAFINSWGNLGGFVAPYMMGYLKDLTQSTTTGMLIISTTLF
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
IGAALVFLIPAKAVNH
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SESSTESLSQPTQLQEENNAYRKTVWHLLPLLMLCYVLNYLDRVNVGFAKLQMADDLQF
CCCCCHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCH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HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]