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The map label for this gene is xylB [H]

Identifier: 218928442

GI number: 218928442

Start: 1449944

End: 1451497

Strand: Direct

Name: xylB [H]

Synonym: YPO1291

Alternate gene names: 218928442

Gene position: 1449944-1451497 (Clockwise)

Preceding gene: 218928441

Following gene: 218928443

Centisome position: 31.16

GC content: 58.49

Gene sequence:

>1554_bases
ATGCAGGCGCTTTTGGGCATTGATATCGGCACCTCGGGGTGTAAGGCGTTGCTGATCGGTATCGATGGTGCGGTGATCGC
CGCCGATACCGCGAGTTATCCATTATCTCAACCCCAACTCGGTTGGGCTGAACAAGATCCTGAGCTGTGGGTCGAGGGGG
CGCGTCGAGCCGTGGCAGGAGCATTGGCTAAAGCGCCAACGCTGGAGTTGCTCTGCGTGGGGCTATCCGGGCAAATGCAT
GGGCTGGTATCACTTGATGCTGGGCATCAGGTGTTGCGCCCGGCGATCCTCTGGAACGACCAACGCAATAGTGCTGAATG
CGAGCAGATTACCGAGGCAGCGGGGGGGCTAAAAGGATTGTTGGCGGCGACTAACAACCGAATGTTGGTGGGCTACACCG
GTGGTAAGATTGTGTGGATGCAGCAGCATGAGCCTGATCTCTTCGCTCGCATGACCACCGTACTGAACCCCAAAGACTAC
TTGCGGCTGCGTTTGACGGGGGAGGTCGCCACTGAAGTTTCGGATGCCTCGGGGACCGGGCTTTTCGATGTACGTGCACG
CCAGTGGGCGAGCGATCTTATTGAGAACGTGGGGATTGACCGCGCTTTACTGCCCCCCGTATTTGAATCGCAGGTGATCT
CTGGCCAGGTCTCAGCGGTGGGGGCCGAGCTATTCGGTATTCCCAAAGGCACGCCCGTTGCTGGTGGTGGCGGTGATGCT
GTGATACAGACCTTCGGTTCTGGGGTGATCGCTCCGGGTGAGTTACAAACCACCATCGGCACGGCGGGCATCCTTGCAGC
GGCATTGGATACACCACAGGCGAACCCCGACGGGCGGTTACAGGTTTTTTGTCATGTTGTGGCTGATAAATGGCACTGCA
TGGGGGTCTCGCTGAACGCTGGCGGCGCGATGAGTTGGTTTCGTGACACGTTTTATGTGGGTGTTAATGCGGCGGTTCCT
TCTTTTGATCAGTTCACACCTTCTGATCAGATCACACCTTCTTTTGAGCAGATCGTTGCTGAGGCGGCAGCCAGCCCGGC
AGGGGCGCGCGGTCTGCTGTTCTTACCTTATCTGAATGGTGAACGTTGCCCTCATCCTGATCCTGCGGCGCGCGGTGCCT
TCATTGGTCTGACAGCCTGCCACAATCGTGGCGATGTGGCACGTGCAGTCATGGAGGGGGTGGTCCACGCCCTTGTGGAT
ATGCACACCTTGATGAAGCCATTGGGCATCAATGGGCGGGTTGTAAAAACATCCGGTGGCGGTGCACGTTCGCCCCTTTG
GCGGCAGATGCAGGCAGATATTTTCGGCTGTGATGTCCTTACCACAAAAGGGGCTGCTGAAGGCGCCGCATTCGGTGCCG
CGCTGGTGGCGGGATTGGCTATCGGGGTTTGGCCCGATGCGACGAGCGCGACGGCGAACTGCCGTATCATCACGCGCGAA
CCCCCCAATCCCGCAACCGCGGCGGTTGTTGCTGAGGCCCAACGCATTTACCGTACTCTTTACCCGGCGCTGAGAGAAAC
CTTCGCAGAACTTGGCGACCCCACCTTTATGTAG

Upstream 100 bases:

>100_bases
TAAGCAAAGTGGTGTGGGCTACGAGCATGGCCGTGAGGGGTTGCTGGAGTATTTCAATTTCAAGCACATCCGCTTGTACC
ACGGTATCGGGGACTAAACC

Downstream 100 bases:

>100_bases
TCATGATCAGGAGTCACGAATGAGCAATCAACAAAATGACGCCAAGAGGGCTGCCGCCCGTCGGGTGATTCAGGATTTCG
TGTTCGATGGCATGACGTTG

Product: putative carbohydrate kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MQALLGIDIGTSGCKALLIGIDGAVIAADTASYPLSQPQLGWAEQDPELWVEGARRAVAGALAKAPTLELLCVGLSGQMH
GLVSLDAGHQVLRPAILWNDQRNSAECEQITEAAGGLKGLLAATNNRMLVGYTGGKIVWMQQHEPDLFARMTTVLNPKDY
LRLRLTGEVATEVSDASGTGLFDVRARQWASDLIENVGIDRALLPPVFESQVISGQVSAVGAELFGIPKGTPVAGGGGDA
VIQTFGSGVIAPGELQTTIGTAGILAAALDTPQANPDGRLQVFCHVVADKWHCMGVSLNAGGAMSWFRDTFYVGVNAAVP
SFDQFTPSDQITPSFEQIVAEAAASPAGARGLLFLPYLNGERCPHPDPAARGAFIGLTACHNRGDVARAVMEGVVHALVD
MHTLMKPLGINGRVVKTSGGGARSPLWRQMQADIFGCDVLTTKGAAEGAAFGAALVAGLAIGVWPDATSATANCRIITRE
PPNPATAAVVAEAQRIYRTLYPALRETFAELGDPTFM

Sequences:

>Translated_517_residues
MQALLGIDIGTSGCKALLIGIDGAVIAADTASYPLSQPQLGWAEQDPELWVEGARRAVAGALAKAPTLELLCVGLSGQMH
GLVSLDAGHQVLRPAILWNDQRNSAECEQITEAAGGLKGLLAATNNRMLVGYTGGKIVWMQQHEPDLFARMTTVLNPKDY
LRLRLTGEVATEVSDASGTGLFDVRARQWASDLIENVGIDRALLPPVFESQVISGQVSAVGAELFGIPKGTPVAGGGGDA
VIQTFGSGVIAPGELQTTIGTAGILAAALDTPQANPDGRLQVFCHVVADKWHCMGVSLNAGGAMSWFRDTFYVGVNAAVP
SFDQFTPSDQITPSFEQIVAEAAASPAGARGLLFLPYLNGERCPHPDPAARGAFIGLTACHNRGDVARAVMEGVVHALVD
MHTLMKPLGINGRVVKTSGGGARSPLWRQMQADIFGCDVLTTKGAAEGAAFGAALVAGLAIGVWPDATSATANCRIITRE
PPNPATAAVVAEAQRIYRTLYPALRETFAELGDPTFM
>Mature_517_residues
MQALLGIDIGTSGCKALLIGIDGAVIAADTASYPLSQPQLGWAEQDPELWVEGARRAVAGALAKAPTLELLCVGLSGQMH
GLVSLDAGHQVLRPAILWNDQRNSAECEQITEAAGGLKGLLAATNNRMLVGYTGGKIVWMQQHEPDLFARMTTVLNPKDY
LRLRLTGEVATEVSDASGTGLFDVRARQWASDLIENVGIDRALLPPVFESQVISGQVSAVGAELFGIPKGTPVAGGGGDA
VIQTFGSGVIAPGELQTTIGTAGILAAALDTPQANPDGRLQVFCHVVADKWHCMGVSLNAGGAMSWFRDTFYVGVNAAVP
SFDQFTPSDQITPSFEQIVAEAAASPAGARGLLFLPYLNGERCPHPDPAARGAFIGLTACHNRGDVARAVMEGVVHALVD
MHTLMKPLGINGRVVKTSGGGARSPLWRQMQADIFGCDVLTTKGAAEGAAFGAALVAGLAIGVWPDATSATANCRIITRE
PPNPATAAVVAEAQRIYRTLYPALRETFAELGDPTFM

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI88196792, Length=499, Percent_Identity=24.0480961923848, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI41393575, Length=436, Percent_Identity=25.2293577981651, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI42794763, Length=455, Percent_Identity=24.6153846153846, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI189409120, Length=455, Percent_Identity=24.8351648351648, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI4504007, Length=455, Percent_Identity=24.8351648351648, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI18860918, Length=259, Percent_Identity=23.5521235521236, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1789987, Length=507, Percent_Identity=36.2919132149901, Blast_Score=295, Evalue=4e-81,
Organism=Escherichia coli, GI1790005, Length=527, Percent_Identity=28.4629981024668, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1787789, Length=374, Percent_Identity=26.4705882352941, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790361, Length=496, Percent_Identity=25.4032258064516, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1789168, Length=433, Percent_Identity=23.3256351039261, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17535599, Length=464, Percent_Identity=24.7844827586207, Blast_Score=102, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6321633, Length=345, Percent_Identity=22.3188405797101, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17864214, Length=482, Percent_Identity=24.2738589211618, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24655555, Length=460, Percent_Identity=22.8260869565217, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24655560, Length=460, Percent_Identity=22.8260869565217, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24655570, Length=460, Percent_Identity=22.8260869565217, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24655574, Length=460, Percent_Identity=22.8260869565217, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24655565, Length=460, Percent_Identity=22.8260869565217, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24654573, Length=413, Percent_Identity=23.9709443099274, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356607, Length=554, Percent_Identity=21.4801444043321, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 54067; Mature: 54067

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALLGIDIGTSGCKALLIGIDGAVIAADTASYPLSQPQLGWAEQDPELWVEGARRAVAG
CCCEEEEECCCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ALAKAPTLELLCVGLSGQMHGLVSLDAGHQVLRPAILWNDQRNSAECEQITEAAGGLKGL
HHHCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHEEECCCCCCHHHHHHHHHHCCHHEE
LAATNNRMLVGYTGGKIVWMQQHEPDLFARMTTVLNPKDYLRLRLTGEVATEVSDASGTG
EEECCCEEEEEECCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEEECHHHHHCCCCCCCC
LFDVRARQWASDLIENVGIDRALLPPVFESQVISGQVSAVGAELFGIPKGTPVAGGGGDA
EEEHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHH
VIQTFGSGVIAPGELQTTIGTAGILAAALDTPQANPDGRLQVFCHVVADKWHCMGVSLNA
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEEEEEEEECC
GGAMSWFRDTFYVGVNAAVPSFDQFTPSDQITPSFEQIVAEAAASPAGARGLLFLPYLNG
CCCHHHHHCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCC
ERCPHPDPAARGAFIGLTACHNRGDVARAVMEGVVHALVDMHTLMKPLGINGRVVKTSGG
CCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
GARSPLWRQMQADIFGCDVLTTKGAAEGAAFGAALVAGLAIGVWPDATSATANCRIITRE
CCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHEECCCCCCCCCCEEEEEECC
PPNPATAAVVAEAQRIYRTLYPALRETFAELGDPTFM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQALLGIDIGTSGCKALLIGIDGAVIAADTASYPLSQPQLGWAEQDPELWVEGARRAVAG
CCCEEEEECCCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ALAKAPTLELLCVGLSGQMHGLVSLDAGHQVLRPAILWNDQRNSAECEQITEAAGGLKGL
HHHCCCCEEEEEEECCCCCCEEEEECCCHHHHHHHEEECCCCCCHHHHHHHHHHCCHHEE
LAATNNRMLVGYTGGKIVWMQQHEPDLFARMTTVLNPKDYLRLRLTGEVATEVSDASGTG
EEECCCEEEEEECCCEEEEEECCCCHHHHHHHHHCCCCCEEEEEEECHHHHHCCCCCCCC
LFDVRARQWASDLIENVGIDRALLPPVFESQVISGQVSAVGAELFGIPKGTPVAGGGGDA
EEEHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHH
VIQTFGSGVIAPGELQTTIGTAGILAAALDTPQANPDGRLQVFCHVVADKWHCMGVSLNA
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEEEEEEEECC
GGAMSWFRDTFYVGVNAAVPSFDQFTPSDQITPSFEQIVAEAAASPAGARGLLFLPYLNG
CCCHHHHHCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCC
ERCPHPDPAARGAFIGLTACHNRGDVARAVMEGVVHALVDMHTLMKPLGINGRVVKTSGG
CCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
GARSPLWRQMQADIFGCDVLTTKGAAEGAAFGAALVAGLAIGVWPDATSATANCRIITRE
CCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHEECCCCCCCCCCEEEEEECC
PPNPATAAVVAEAQRIYRTLYPALRETFAELGDPTFM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]