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The map label for this gene is nreC [H]

Identifier: 218927460

GI number: 218927460

Start: 255039

End: 255671

Strand: Reverse

Name: nreC [H]

Synonym: YPO0255

Alternate gene names: 218927460

Gene position: 255671-255039 (Counterclockwise)

Preceding gene: 218927461

Following gene: 218927458

Centisome position: 5.49

GC content: 45.02

Gene sequence:

>633_bases
ATGAATACTAAATTATTGATTGTCGACGATCATGAACTCATTATTCATGGCATCAAGAATATGCTGGCCGCCTATCCGCG
CTACCTGATTGTAGGCCAAGCGGATAATGGACTTGAAGTGTATAACTTGTGCCGCCAAACTGAACCTGACATGGTCATTC
TGGATTTAGGATTACCCGGTATGGATGGCCTTGATGTTATCATTCAGTTGCTTCGCCGTTGGCCAGCCCTGAAGATCCTG
ACGTTAACCGCCCGCAATGAAGAACACTATGCCAGCAGAACATTCAACAGTGGAGCCTTAGGTTATGTGCTGAAGAAAAG
TCCCCAGCAAATCCTGATGGCAGCCATTCAAACCGTCGCAATAGGTAAACGTTATATTGACCCCGCCCTTGATGCCTCTA
TGGTAATAAAACTGACCCAAGGATCCGATAATACGCCCCCGGTTCTGACACCTCGCGAGCGGCAGATATTAAAACTTATC
ACCGAGGGATCGTGTAATCGAGTTATTGCTGCTCAACTTTCTATCAGCCAAAAAACCGTCGAAACACATCGGCTGAATAT
GATGAAAAAATTGGATGTACATAAAGTCGCAGAACTTATTCACTGGTCATACCGATTAGGCTTGAATGTCTAA

Upstream 100 bases:

>100_bases
TGAAATAATTCATGTGCTGCTACAGCCCCCCACTACCTGCGAATCCACGTTTATCATCAGCCAGGGCCAGTCCCTTATGG
TTAAATAAAGAGAATGACGA

Downstream 100 bases:

>100_bases
TGCCAGTATGTGATTTTTCTACTTATTACTTATGTTGGCGATAAATAAATGTTGGCGACAAATAAAAACTCCCCGTCAGT
ATGATGCTGACGGGGAGTGG

Product: putative two-component response regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MNTKLLIVDDHELIIHGIKNMLAAYPRYLIVGQADNGLEVYNLCRQTEPDMVILDLGLPGMDGLDVIIQLLRRWPALKIL
TLTARNEEHYASRTFNSGALGYVLKKSPQQILMAAIQTVAIGKRYIDPALDASMVIKLTQGSDNTPPVLTPRERQILKLI
TEGSCNRVIAAQLSISQKTVETHRLNMMKKLDVHKVAELIHWSYRLGLNV

Sequences:

>Translated_210_residues
MNTKLLIVDDHELIIHGIKNMLAAYPRYLIVGQADNGLEVYNLCRQTEPDMVILDLGLPGMDGLDVIIQLLRRWPALKIL
TLTARNEEHYASRTFNSGALGYVLKKSPQQILMAAIQTVAIGKRYIDPALDASMVIKLTQGSDNTPPVLTPRERQILKLI
TEGSCNRVIAAQLSISQKTVETHRLNMMKKLDVHKVAELIHWSYRLGLNV
>Mature_210_residues
MNTKLLIVDDHELIIHGIKNMLAAYPRYLIVGQADNGLEVYNLCRQTEPDMVILDLGLPGMDGLDVIIQLLRRWPALKIL
TLTARNEEHYASRTFNSGALGYVLKKSPQQILMAAIQTVAIGKRYIDPALDASMVIKLTQGSDNTPPVLTPRERQILKLI
TEGSCNRVIAAQLSISQKTVETHRLNMMKKLDVHKVAELIHWSYRLGLNV

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=206, Percent_Identity=33.9805825242718, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1788521, Length=206, Percent_Identity=31.5533980582524, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786747, Length=203, Percent_Identity=31.5270935960591, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787473, Length=182, Percent_Identity=33.5164835164835, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1790102, Length=193, Percent_Identity=30.5699481865285, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788712, Length=200, Percent_Identity=29.5, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788546, Length=204, Percent_Identity=27.4509803921569, Blast_Score=78, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23576; Mature: 23576

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKLLIVDDHELIIHGIKNMLAAYPRYLIVGQADNGLEVYNLCRQTEPDMVILDLGLPG
CCCEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCC
MDGLDVIIQLLRRWPALKILTLTARNEEHYASRTFNSGALGYVLKKSPQQILMAAIQTVA
CCCHHHHHHHHHHCCCEEEEEEEECCCHHHHHHCCCCCCEEHHHHCCHHHHHHHHHHHHH
IGKRYIDPALDASMVIKLTQGSDNTPPVLTPRERQILKLITEGSCNRVIAAQLSISQKTV
HHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEHHHHHHH
ETHRLNMMKKLDVHKVAELIHWSYRLGLNV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTKLLIVDDHELIIHGIKNMLAAYPRYLIVGQADNGLEVYNLCRQTEPDMVILDLGLPG
CCCEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCC
MDGLDVIIQLLRRWPALKILTLTARNEEHYASRTFNSGALGYVLKKSPQQILMAAIQTVA
CCCHHHHHHHHHHCCCEEEEEEEECCCHHHHHHCCCCCCEEHHHHCCHHHHHHHHHHHHH
IGKRYIDPALDASMVIKLTQGSDNTPPVLTPRERQILKLITEGSCNRVIAAQLSISQKTV
HHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEHHHHHHH
ETHRLNMMKKLDVHKVAELIHWSYRLGLNV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]