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The map label for this gene is nuoN [H]

Identifier: 218906467

GI number: 218906467

Start: 5082157

End: 5083677

Strand: Reverse

Name: nuoN [H]

Synonym: BCAH820_5381

Alternate gene names: 218906467

Gene position: 5083677-5082157 (Counterclockwise)

Preceding gene: 218906468

Following gene: 218906466

Centisome position: 95.87

GC content: 38.92

Gene sequence:

>1521_bases
ATGGATATGAATACGTTACTTAGCTTATCGTGGCATCTCATGGTGCCAGAATTCATCATTCTCGGGGCTGCCATCCTTCT
TTCCATATGTGATTTGTTTTTTAAGCTGAACCATAGATACGTAGCGCTTGGTGCAATCGCGGCGGTCGTATTAGCAATCG
TGTCACTAATTACGCTATATGGCGAACCAGCGGGAGATATTTTAAATGGATCGTTTGTGTTAGATGGATTTTCAAAAGGA
TTTAAAACGTTGTTGTTAGGCGGGGCGGCGCTCATTTTGTGTACCGCAATGAGCGATGATAAGAAAAATCCAATTGAAGA
TAAGGGAGAGTATTATTACTTATTTTTAATGGCGCTTCTTGGGGCGATGTTTATGGCTTCTAGCGTTGATTTCGTTACAC
TTTTCATCGGTTTAGAATTGCTTTCACTTTCCTCCTACATTTTAGTAGGAATACGAAAAAAGAACCGTGCATCAAATGAG
GCAGCAATGAAATATGTCATTAATGGAGGAATTGGAACGGCAATTACACTCTTTGGAATGAGTTATTTATACGGTATTAC
AGGCTCAACCAATATGGTGGATATGCAAAAAGTATTTGCCGGGGAACTGGCTAGTGGCATTCAGTTATTACTAGCTCTCG
CATTTCTACTCTTACTCGTTGGGCTCTCATTCAAAATTGCGACAGTGCCGTTTCATATGTGGGCACCTGATGTGTATGAG
GGAGCAGCTACACCTGTTACTGCTTTTCTTGGAACAATTTCTAAAATGGCGGGTTTCTTACTCATCATTCGTTTGTTCCT
CATGGTTTTTGCAAGTGTATCGGTGCAAGGAGACATGCAATCTTTATACGGACGTATGAGCATATATATCGCTGTGCTAG
CTAGTATTACGATGATTATTGGAAATGTAGTCGCATTAAAGCAATATAACGTAAAACGCCTATTTGCTTATTCGGGAATC
GCGCATGCGGGATATTTACTCGTTCCGCTTGTCGCATTATCACCATTTACGATGGATAGTATGTGGTTTTACATGCTTGC
ATATATGCTTATGAATATAGGCGCGTTTGCAATTATCCACGGCTTAATCTTACAAAGCGATAAAGAAAATATCACCATTT
TCACTGGATTATATAAAAGATCGCCATTTACAGCGATTGTGATGACGATTTTTATTTTATCGTTAGCGGGGATACCAGGA
ACAGCTGGTTTCATTGGGAAAATTAACATCTTTTTAGGGGCTCTTCATGTAGAGCCAGCTCATTACGTACTAGCTTCTAT
TATGATGGGGACGACAGTCATTTCATTCGTATATTATTTCCGTATTTTACAACAAATATTTTTCCGGACGGGAGAAGTAG
AAGAGAAAATTCGTTTGCCACTCAATATAAAGATTGTAATGAGCTTTTGTGCAATTTCGATTGTAATACTAGGGATTGTG
CCGATGATTGGATACAATTTCTTTTATGAATATTTTCCATTAATGAAAGATTTCTTCTTCTTAGGGAACGTGGTACAATA
G

Upstream 100 bases:

>100_bases
ATCTTGCTACTTATCTTCTGCATTATTGCAATTGGCGTAATGCCAGAAATACTAGGGGATCCGCTTCAAAATACATTGAA
AACATTGGGGGTGAAGTAGG

Downstream 100 bases:

>100_bases
TGAAAATAAAAGGTGTGGAGTCGTTACTCTGCGCTTTTTATTTTGTGTGAACTACAATTGAAAATACATATAGGTATACG
TTTTTAAAGAGAAAAATTTC

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAVVLAIVSLITLYGEPAGDILNGSFVLDGFSKG
FKTLLLGGAALILCTAMSDDKKNPIEDKGEYYYLFLMALLGAMFMASSVDFVTLFIGLELLSLSSYILVGIRKKNRASNE
AAMKYVINGGIGTAITLFGMSYLYGITGSTNMVDMQKVFAGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYE
GAATPVTAFLGTISKMAGFLLIIRLFLMVFASVSVQGDMQSLYGRMSIYIAVLASITMIIGNVVALKQYNVKRLFAYSGI
AHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIHGLILQSDKENITIFTGLYKRSPFTAIVMTIFILSLAGIPG
TAGFIGKINIFLGALHVEPAHYVLASIMMGTTVISFVYYFRILQQIFFRTGEVEEKIRLPLNIKIVMSFCAISIVILGIV
PMIGYNFFYEYFPLMKDFFFLGNVVQ

Sequences:

>Translated_506_residues
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAVVLAIVSLITLYGEPAGDILNGSFVLDGFSKG
FKTLLLGGAALILCTAMSDDKKNPIEDKGEYYYLFLMALLGAMFMASSVDFVTLFIGLELLSLSSYILVGIRKKNRASNE
AAMKYVINGGIGTAITLFGMSYLYGITGSTNMVDMQKVFAGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYE
GAATPVTAFLGTISKMAGFLLIIRLFLMVFASVSVQGDMQSLYGRMSIYIAVLASITMIIGNVVALKQYNVKRLFAYSGI
AHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIHGLILQSDKENITIFTGLYKRSPFTAIVMTIFILSLAGIPG
TAGFIGKINIFLGALHVEPAHYVLASIMMGTTVISFVYYFRILQQIFFRTGEVEEKIRLPLNIKIVMSFCAISIVILGIV
PMIGYNFFYEYFPLMKDFFFLGNVVQ
>Mature_506_residues
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAVVLAIVSLITLYGEPAGDILNGSFVLDGFSKG
FKTLLLGGAALILCTAMSDDKKNPIEDKGEYYYLFLMALLGAMFMASSVDFVTLFIGLELLSLSSYILVGIRKKNRASNE
AAMKYVINGGIGTAITLFGMSYLYGITGSTNMVDMQKVFAGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYE
GAATPVTAFLGTISKMAGFLLIIRLFLMVFASVSVQGDMQSLYGRMSIYIAVLASITMIIGNVVALKQYNVKRLFAYSGI
AHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIHGLILQSDKENITIFTGLYKRSPFTAIVMTIFILSLAGIPG
TAGFIGKINIFLGALHVEPAHYVLASIMMGTTVISFVYYFRILQQIFFRTGEVEEKIRLPLNIKIVMSFCAISIVILGIV
PMIGYNFFYEYFPLMKDFFFLGNVVQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI145693160, Length=479, Percent_Identity=33.1941544885177, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI1788831, Length=309, Percent_Identity=27.831715210356, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1788613, Length=382, Percent_Identity=23.8219895287958, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788614, Length=364, Percent_Identity=25.8241758241758, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788827, Length=417, Percent_Identity=23.7410071942446, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788829, Length=386, Percent_Identity=22.279792746114, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 55582; Mature: 55582

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAVVLAIVSLITLY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GEPAGDILNGSFVLDGFSKGFKTLLLGGAALILCTAMSDDKKNPIEDKGEYYYLFLMALL
CCCCCCCCCCCEEECCHHHHHHHHHHCCHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHH
GAMFMASSVDFVTLFIGLELLSLSSYILVGIRKKNRASNEAAMKYVINGGIGTAITLFGM
HHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHEECCHHHHHHHHHH
SYLYGITGSTNMVDMQKVFAGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYE
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHC
GAATPVTAFLGTISKMAGFLLIIRLFLMVFASVSVQGDMQSLYGRMSIYIAVLASITMII
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
GNVVALKQYNVKRLFAYSGIAHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIH
HHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLILQSDKENITIFTGLYKRSPFTAIVMTIFILSLAGIPGTAGFIGKINIFLGALHVEPA
HHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEEEECCHH
HYVLASIMMGTTVISFVYYFRILQQIFFRTGEVEEKIRLPLNIKIVMSFCAISIVILGIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
PMIGYNFFYEYFPLMKDFFFLGNVVQ
HHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAVVLAIVSLITLY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GEPAGDILNGSFVLDGFSKGFKTLLLGGAALILCTAMSDDKKNPIEDKGEYYYLFLMALL
CCCCCCCCCCCEEECCHHHHHHHHHHCCHHHHHEEECCCCCCCCCCCCCCCHHHHHHHHH
GAMFMASSVDFVTLFIGLELLSLSSYILVGIRKKNRASNEAAMKYVINGGIGTAITLFGM
HHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHEECCHHHHHHHHHH
SYLYGITGSTNMVDMQKVFAGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYE
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHC
GAATPVTAFLGTISKMAGFLLIIRLFLMVFASVSVQGDMQSLYGRMSIYIAVLASITMII
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
GNVVALKQYNVKRLFAYSGIAHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIH
HHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLILQSDKENITIFTGLYKRSPFTAIVMTIFILSLAGIPGTAGFIGKINIFLGALHVEPA
HHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEEEECCHH
HYVLASIMMGTTVISFVYYFRILQQIFFRTGEVEEKIRLPLNIKIVMSFCAISIVILGIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
PMIGYNFFYEYFPLMKDFFFLGNVVQ
HHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]