Click here to switch to the map view.

The map label for this gene is lytT [H]

Identifier: 218906462

GI number: 218906462

Start: 5077091

End: 5078098

Strand: Reverse

Name: lytT [H]

Synonym: BCAH820_5376

Alternate gene names: 218906462

Gene position: 5078098-5077091 (Counterclockwise)

Preceding gene: 218906463

Following gene: 218906461

Centisome position: 95.76

GC content: 35.42

Gene sequence:

>1008_bases
ATGGCACTACTGGAGTTGAAACAGTTAGGAAAGACAAATCAGTTACCGGCAGTTGAACTGAAGGTTGAGAAGGGACAATG
TGTTGTTTTGCAGTGTAATAACCATACAGCAAAGATTTTGCACCGCATTATTATTGGTGAGGAAGAAGCTTCAACTGGCA
ATGTGCTATTTGAAGATGAAGTGATTGGAAAGAAAAACTATTCCCGCATCGGTTTTTGTTTTTTGAAAGATGAGGCATAT
GATCGTTTGAAGGTAAAGGAATACTTCAAGTTCTTAATAGGGCTTTATAAATCAAATATGAGTACGGAAGAAGTAGTACA
ATCTGTCGGTCTCCTAGATAAATTAAACGTTAAAATAGAAAAACTATCATTTTCAGAGAAACGTCGTCTTCATATTGGGC
GAGTAATGATTCATAATCCAGATTTAGTTATTTTGGAAGAGCCGGAGCAAAATGTAGATACAGAGAGTACGATTATTATT
CGAAAAGCGATTATGAAAATGAAAGAGCAAGGAAAGGCAATTTTTATTACGTCATCATTTCTATCGGATGCCCTTTCGTT
AACAGAAGATGTATACATATTAAATAATGATGGTGTGAAAAAAATAGAAATCGAACAAGAAGAAGCAGAAGAAGTCGATG
AAGAAAAAGTCATTCAAATGATTCCGCAAATGAAGTTAGAAAGAATACCAGCGAAAGTGAACGATAAAATCATTTTATTA
GACCCGATGGAAATTCATTTCATTGAAACGCAAAACGGAGTAACACATATTCATGTGCGCGAAGGTGATTTCGTATGTGC
ATTAACATTAAGCGAACTAGAAACGAGATTAACAGGTTTTGGTTTCTTTAGATGTCATCGCTCGTACCTTGTGAATTTAC
AAAGAGTACGAGAAGTGATTACGTGGACTCGTAATAGCTTTAGTTTAATTTTGGATGACGAAAGAAAAAGTTCAATTCCG
CTTTCGAAAGGACGAATGGATGAATTAAAAGGCGTGATTGGGCTATAA

Upstream 100 bases:

>100_bases
TTGGGACGGTCCTTCTTTTTTTATAATGCTTCATAAAATATCTAAATTTTCCATTAATTGTTTGGTATAATAGGATAAAA
AAGTATTCGGGGGAGACGGA

Downstream 100 bases:

>100_bases
AAAGTGCTCCAATAAGCTCAAAATATGATTCATTCACCGGTAAAAATACTCCTTTTACCGGTATTTTACTGCGTAAACCC
TTTGTTTTTCATATGATGGA

Product: ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MALLELKQLGKTNQLPAVELKVEKGQCVVLQCNNHTAKILHRIIIGEEEASTGNVLFEDEVIGKKNYSRIGFCFLKDEAY
DRLKVKEYFKFLIGLYKSNMSTEEVVQSVGLLDKLNVKIEKLSFSEKRRLHIGRVMIHNPDLVILEEPEQNVDTESTIII
RKAIMKMKEQGKAIFITSSFLSDALSLTEDVYILNNDGVKKIEIEQEEAEEVDEEKVIQMIPQMKLERIPAKVNDKIILL
DPMEIHFIETQNGVTHIHVREGDFVCALTLSELETRLTGFGFFRCHRSYLVNLQRVREVITWTRNSFSLILDDERKSSIP
LSKGRMDELKGVIGL

Sequences:

>Translated_335_residues
MALLELKQLGKTNQLPAVELKVEKGQCVVLQCNNHTAKILHRIIIGEEEASTGNVLFEDEVIGKKNYSRIGFCFLKDEAY
DRLKVKEYFKFLIGLYKSNMSTEEVVQSVGLLDKLNVKIEKLSFSEKRRLHIGRVMIHNPDLVILEEPEQNVDTESTIII
RKAIMKMKEQGKAIFITSSFLSDALSLTEDVYILNNDGVKKIEIEQEEAEEVDEEKVIQMIPQMKLERIPAKVNDKIILL
DPMEIHFIETQNGVTHIHVREGDFVCALTLSELETRLTGFGFFRCHRSYLVNLQRVREVITWTRNSFSLILDDERKSSIP
LSKGRMDELKGVIGL
>Mature_334_residues
ALLELKQLGKTNQLPAVELKVEKGQCVVLQCNNHTAKILHRIIIGEEEASTGNVLFEDEVIGKKNYSRIGFCFLKDEAYD
RLKVKEYFKFLIGLYKSNMSTEEVVQSVGLLDKLNVKIEKLSFSEKRRLHIGRVMIHNPDLVILEEPEQNVDTESTIIIR
KAIMKMKEQGKAIFITSSFLSDALSLTEDVYILNNDGVKKIEIEQEEAEEVDEEKVIQMIPQMKLERIPAKVNDKIILLD
PMEIHFIETQNGVTHIHVREGDFVCALTLSELETRLTGFGFFRCHRSYLVNLQRVREVITWTRNSFSLILDDERKSSIPL
SKGRMDELKGVIGL

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=191, Percent_Identity=24.0837696335079, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 38436; Mature: 38305

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50930 HTH_LYTTR ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLELKQLGKTNQLPAVELKVEKGQCVVLQCNNHTAKILHRIIIGEEEASTGNVLFEDE
CCCHHHHHCCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHCCCCCCCCCCEEEECC
VIGKKNYSRIGFCFLKDEAYDRLKVKEYFKFLIGLYKSNMSTEEVVQSVGLLDKLNVKIE
CCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHCCCEEE
KLSFSEKRRLHIGRVMIHNPDLVILEEPEQNVDTESTIIIRKAIMKMKEQGKAIFITSSF
EECCCCCCCEEEEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHH
LSDALSLTEDVYILNNDGVKKIEIEQEEAEEVDEEKVIQMIPQMKLERIPAKVNDKIILL
HHHHHHHCCCEEEECCCCEEEEEECHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEE
DPMEIHFIETQNGVTHIHVREGDFVCALTLSELETRLTGFGFFRCHRSYLVNLQRVREVI
CCCEEEEEEECCCEEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TWTRNSFSLILDDERKSSIPLSKGRMDELKGVIGL
HHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
ALLELKQLGKTNQLPAVELKVEKGQCVVLQCNNHTAKILHRIIIGEEEASTGNVLFEDE
CCHHHHHCCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHCCCCCCCCCCEEEECC
VIGKKNYSRIGFCFLKDEAYDRLKVKEYFKFLIGLYKSNMSTEEVVQSVGLLDKLNVKIE
CCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHCCCEEE
KLSFSEKRRLHIGRVMIHNPDLVILEEPEQNVDTESTIIIRKAIMKMKEQGKAIFITSSF
EECCCCCCCEEEEEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHH
LSDALSLTEDVYILNNDGVKKIEIEQEEAEEVDEEKVIQMIPQMKLERIPAKVNDKIILL
HHHHHHHCCCEEEECCCCEEEEEECHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEE
DPMEIHFIETQNGVTHIHVREGDFVCALTLSELETRLTGFGFFRCHRSYLVNLQRVREVI
CCCEEEEEEECCCEEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TWTRNSFSLILDDERKSSIPLSKGRMDELKGVIGL
HHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]