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The map label for this gene is ppaX [H]

Identifier: 218906333

GI number: 218906333

Start: 4943108

End: 4943758

Strand: Reverse

Name: ppaX [H]

Synonym: BCAH820_5246

Alternate gene names: 218906333

Gene position: 4943758-4943108 (Counterclockwise)

Preceding gene: 218906334

Following gene: 218906332

Centisome position: 93.23

GC content: 34.56

Gene sequence:

>651_bases
ATGAAAATAAATACAGTGTTATTTGATTTAGATGGAACGTTAATTAATACAAACGAACTTATTATTTCTTCTTTTTTACA
TACTTTACATACATATTATCCAAATCAATATAAGCGTGAAGATGTATTGCCTTTTATCGGTCCATCTTTACATGATACTT
TCAGTAAGATTGATGAAAGTAAGGTTGAAGAGTTAATTACGAGTTATCGTCAATTTAACCATGATCATCATGATGAATTA
GTAGAAGAATATGAAACTGTATATGAAACAGTTCAAGAGTTAAAGAAGCAAGGCTATAAGGTTGGTATTGTTACAACGAA
AGCACGACAAACTGTTGAGATGGGATTGAAGTTATCAAAGCTTGATGAGTTTTTTGATGTTGTCGTGACAATTGATGATG
TAGAGCATGTGAAACCACATCCAGAGCCACTTCAAAAAGCGCTTCAGTTATTAGGTGCGAAACCAGAAGAAGCATTGATG
GTTGGGGATAATCATCATGATATTGTTGGCGGACAAAATGCGGGTACGAAAACAGCTGCGGTTTCATGGACATTGAAAGG
TAGAGCGTATTTAGAAGCTTACAAGCCAGACTTTATGCTAGATAAAATGAGTGATTTATTGCCGATTTTGTCCGACATGA
ATCGTTCGTAA

Upstream 100 bases:

>100_bases
GGGCAAGCTGATAAAAGATATTCGGAAAATTAGAGACAAGTAGCATCTTATTATAAGATGCTGCTTCTTTCATATTCAGG
AAAGAGAAAGGACTAAGGCA

Downstream 100 bases:

>100_bases
AGATAAGTAGAGGAGCGATTTAAGTGCGACGGACAACGCGCTATCCTGTTTCAGGAGAAAATTCACTATGGAATGTGTAT
AAAACAGTGTCTTTTTGGAA

Product: pyrophosphatase PpaX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKINTVLFDLDGTLINTNELIISSFLHTLHTYYPNQYKREDVLPFIGPSLHDTFSKIDESKVEELITSYRQFNHDHHDEL
VEEYETVYETVQELKKQGYKVGIVTTKARQTVEMGLKLSKLDEFFDVVVTIDDVEHVKPHPEPLQKALQLLGAKPEEALM
VGDNHHDIVGGQNAGTKTAAVSWTLKGRAYLEAYKPDFMLDKMSDLLPILSDMNRS

Sequences:

>Translated_216_residues
MKINTVLFDLDGTLINTNELIISSFLHTLHTYYPNQYKREDVLPFIGPSLHDTFSKIDESKVEELITSYRQFNHDHHDEL
VEEYETVYETVQELKKQGYKVGIVTTKARQTVEMGLKLSKLDEFFDVVVTIDDVEHVKPHPEPLQKALQLLGAKPEEALM
VGDNHHDIVGGQNAGTKTAAVSWTLKGRAYLEAYKPDFMLDKMSDLLPILSDMNRS
>Mature_216_residues
MKINTVLFDLDGTLINTNELIISSFLHTLHTYYPNQYKREDVLPFIGPSLHDTFSKIDESKVEELITSYRQFNHDHHDEL
VEEYETVYETVQELKKQGYKVGIVTTKARQTVEMGLKLSKLDEFFDVVVTIDDVEHVKPHPEPLQKALQLLGAKPEEALM
VGDNHHDIVGGQNAGTKTAAVSWTLKGRAYLEAYKPDFMLDKMSDLLPILSDMNRS

Specific function: Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool [H]

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. PpaX family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=234, Percent_Identity=26.4957264957265, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 24663; Mature: 24663

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINTVLFDLDGTLINTNELIISSFLHTLHTYYPNQYKREDVLPFIGPSLHDTFSKIDES
CCCEEEEEECCCCEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
KVEELITSYRQFNHDHHDELVEEYETVYETVQELKKQGYKVGIVTTKARQTVEMGLKLSK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCHHHH
LDEFFDVVVTIDDVEHVKPHPEPLQKALQLLGAKPEEALMVGDNHHDIVGGQNAGTKTAA
HHHHHHHHHEECCHHHCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCEEE
VSWTLKGRAYLEAYKPDFMLDKMSDLLPILSDMNRS
EEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKINTVLFDLDGTLINTNELIISSFLHTLHTYYPNQYKREDVLPFIGPSLHDTFSKIDES
CCCEEEEEECCCCEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
KVEELITSYRQFNHDHHDELVEEYETVYETVQELKKQGYKVGIVTTKARQTVEMGLKLSK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCHHHH
LDEFFDVVVTIDDVEHVKPHPEPLQKALQLLGAKPEEALMVGDNHHDIVGGQNAGTKTAA
HHHHHHHHHEECCHHHCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCEEE
VSWTLKGRAYLEAYKPDFMLDKMSDLLPILSDMNRS
EEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA