Click here to switch to the map view.

The map label for this gene is estA [H]

Identifier: 218906303

GI number: 218906303

Start: 4917164

End: 4917907

Strand: Reverse

Name: estA [H]

Synonym: BCAH820_5215

Alternate gene names: 218906303

Gene position: 4917907-4917164 (Counterclockwise)

Preceding gene: 218906304

Following gene: 218906302

Centisome position: 92.74

GC content: 38.31

Gene sequence:

>744_bases
ATGATGAAATTAGCATCTCCGAAACCATTTACATTTGAGGGTGGAGACCGCGCTGTTTTATTACTACATGGATTCACAGG
AAACTCAGCTGATGTACGTATGTTAGGGCGTTTCTTAGAAAAGAAAGGCTACACTTGTCATGCGCCAATTTATAAAGGGC
ACGGAGTACCACCAGAAGAGCTTGTTCATACAGGTCCTGAAGATTGGTGGCAAGATGTAACGGAAGCATATCAGCTTTTA
AAAGATAAAGGGTTTGAGAAAATTGCTGTCGTTGGATTGTCACTTGGCGGAGTTTTTTCACTAAAATTAGGTTATACAGT
ACCGGTTTTAGGTGTAGTACCAATGTGTGCACCAATGTATATTAAGAGTGAAGAAACGATGTACCAAGGTATATTGGCAT
ATGCCCGCGAATATAAAAAACGTGAGCAAAAATCACCAGAGCAAATCGAACAAGAAATGTTGGAATTCCAAAAGACACCG
ATGAATACATTAAAAGCATTACAACAATTAATTGCTGACGTACGTAACAATGTGGACATGATTTATGCACCAACATTTGT
TGTACAAGCGCGTCATGATGAAATGATTAATACAGATAGTGCGAACATTATTTATAACGGTGTAGAATCAACGTTAAAAG
ACATTAAATGGTATGAAGACTCTACGCATGTCATTACACTTGATAAGCAGCGTGACGAGCTACATGAGGATGTATATAAC
TTCTTGGAGCAACTAGATTGGTAA

Upstream 100 bases:

>100_bases
ATTTGAAAGATGTTTCTAATTAGATTATAGAAATACAAATATGGTACACTAGATATAGAAAGAATACGACTAGATTACAG
AAGAGAAAGAGGAGAAGTAC

Downstream 100 bases:

>100_bases
GATCTAGTTGCCTCTTTTTTTCATAAGGAATTTTTTGTGAAAACTGTAAAAATCATAAGGGGAGTATTGAAGTTTCACTT
TATACATCCCCTATCTTTCG

Product: carboxylesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MMKLASPKPFTFEGGDRAVLLLHGFTGNSADVRMLGRFLEKKGYTCHAPIYKGHGVPPEELVHTGPEDWWQDVTEAYQLL
KDKGFEKIAVVGLSLGGVFSLKLGYTVPVLGVVPMCAPMYIKSEETMYQGILAYAREYKKREQKSPEQIEQEMLEFQKTP
MNTLKALQQLIADVRNNVDMIYAPTFVVQARHDEMINTDSANIIYNGVESTLKDIKWYEDSTHVITLDKQRDELHEDVYN
FLEQLDW

Sequences:

>Translated_247_residues
MMKLASPKPFTFEGGDRAVLLLHGFTGNSADVRMLGRFLEKKGYTCHAPIYKGHGVPPEELVHTGPEDWWQDVTEAYQLL
KDKGFEKIAVVGLSLGGVFSLKLGYTVPVLGVVPMCAPMYIKSEETMYQGILAYAREYKKREQKSPEQIEQEMLEFQKTP
MNTLKALQQLIADVRNNVDMIYAPTFVVQARHDEMINTDSANIIYNGVESTLKDIKWYEDSTHVITLDKQRDELHEDVYN
FLEQLDW
>Mature_247_residues
MMKLASPKPFTFEGGDRAVLLLHGFTGNSADVRMLGRFLEKKGYTCHAPIYKGHGVPPEELVHTGPEDWWQDVTEAYQLL
KDKGFEKIAVVGLSLGGVFSLKLGYTVPVLGVVPMCAPMYIKSEETMYQGILAYAREYKKREQKSPEQIEQEMLEFQKTP
MNTLKALQQLIADVRNNVDMIYAPTFVVQARHDEMINTDSANIIYNGVESTLKDIKWYEDSTHVITLDKQRDELHEDVYN
FLEQLDW

Specific function: Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates, with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones [H]

COG id: COG1647

COG function: function code R; Esterase/lipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012354
- InterPro:   IPR001375 [H]

Pfam domain/function: PF00326 Peptidase_S9 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 28256; Mature: 28256

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKLASPKPFTFEGGDRAVLLLHGFTGNSADVRMLGRFLEKKGYTCHAPIYKGHGVPPEE
CCCCCCCCCEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCHHH
LVHTGPEDWWQDVTEAYQLLKDKGFEKIAVVGLSLGGVFSLKLGYTVPVLGVVPMCAPMY
HHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHCCCE
IKSEETMYQGILAYAREYKKREQKSPEQIEQEMLEFQKTPMNTLKALQQLIADVRNNVDM
ECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCE
IYAPTFVVQARHDEMINTDSANIIYNGVESTLKDIKWYEDSTHVITLDKQRDELHEDVYN
EEECEEEEEECCCHHCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHH
FLEQLDW
HHHHHCC
>Mature Secondary Structure
MMKLASPKPFTFEGGDRAVLLLHGFTGNSADVRMLGRFLEKKGYTCHAPIYKGHGVPPEE
CCCCCCCCCEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCHHH
LVHTGPEDWWQDVTEAYQLLKDKGFEKIAVVGLSLGGVFSLKLGYTVPVLGVVPMCAPMY
HHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHCCCE
IKSEETMYQGILAYAREYKKREQKSPEQIEQEMLEFQKTPMNTLKALQQLIADVRNNVDM
ECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCE
IYAPTFVVQARHDEMINTDSANIIYNGVESTLKDIKWYEDSTHVITLDKQRDELHEDVYN
EEECEEEEEECCCHHCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHH
FLEQLDW
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1369099 [H]