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The map label for this gene is ald2 [H]

Identifier: 218905853

GI number: 218905853

Start: 4490843

End: 4491976

Strand: Reverse

Name: ald2 [H]

Synonym: BCAH820_4741

Alternate gene names: 218905853

Gene position: 4491976-4490843 (Counterclockwise)

Preceding gene: 218905854

Following gene: 218905852

Centisome position: 84.71

GC content: 39.77

Gene sequence:

>1134_bases
ATGCGTATCGGTATTCCAACAGAAATTAAAAACAATGAAAACCGCGTGGCAATGACGCCAGCGGGAGCAGTACATTTAGT
ACAAAATGGTCATGAAGTTTTTGTTCAAAAAGGAGCAGGTTTAGGATCTGGCTTTACGGATGAAGAATACGTACAAGCTG
GTGCGAAACTTGTTGAAACTGCTGAAGAAGCATGGAATCAAGATATGGTTATGAAGGTAAAAGAGCCAGTTGCAAGTGAA
TACGGCTATTTCCGTGAAGGTTTAATTTTATTCACATACTTACACTTAGCTCCAGAACCAGAATTAACGAAAGCATTAAT
TGATAACAAAGTTGTATCAATTGCATATGAAACAGTACAATTAGACAATCGTTTATTACCATTACTTGCACCTATGAGTG
AAGTAGCAGGTCGTATGTCTGCACAAATCGGTGCACAATTCCTTGAGAAAAACAAAGGCGGTAAAGGTATTTTACTTGCA
GGCGTTCCAGGGGTAAAACGCGGCAAAGTAACAATTATCGGCGGTGGTCAAGCTGGTACAAACGCAGCGAAGATTGCAGT
AGGTTTAGGTGCAGATGTAACAATCATCGACTTAAGTGCAGAACGTCTTCGTCAATTAGATGACATTTTCGGTAACCAAG
TAAAAACGTTAATGTCTAATCCATACAATATTGCAGAAGCTGTAAAAGAATCTGACCTTGTTATTGGTGCGGTATTAATT
CCAGGTGCAAAAGCGCCAAAACTTGTAACAGAAGAAATGATTCAATCAATGGAACCAGGTTCTGTCGTTGTAGATATCGC
GATTGACCAAGGTGGTATTTTCGAAACAACTGACCGTATTACAACTCACGACAACCCAACTTACGAAAAACATGGCGTTG
TTCATTATGCAGTTGCGAATATGCCAGGTGCGGTTCCACGTACATCAACTCTTGCATTAACAAACGTAACAGTACCATAT
GCAGTGCAAATTGCGAACAAAGGCTATAAAGATGCTTGCCTAGGCAACACTGCATTATTAAAAGGTATTAACACATTAGA
TGGATATGTAACATTCGAAGCGGTTGCAGAAGCTCACGGTTTACAATACGCTGATGCAAAAGAGCTTCTTGAAAAAGCTC
CTGCTTTATCATAA

Upstream 100 bases:

>100_bases
TTTTGTCAAATATTGAGATATTATGTTAAAATATAAGAGCGTAGAAAGCGCTTTAAAAAATGATTCAGGGGTCATTTCAT
AACTCAAGGGGGAACTAATA

Downstream 100 bases:

>100_bases
TTAAAATATATGTAGCCTTCCTTTTTTTAGGAGGGCTTTTATTTAAAATAAAAACATCTTATAATATAGATAATAAGAAA
TTAGGATAAGAATGGGAGGC

Product: alanine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MRIGIPTEIKNNENRVAMTPAGAVHLVQNGHEVFVQKGAGLGSGFTDEEYVQAGAKLVETAEEAWNQDMVMKVKEPVASE
YGYFREGLILFTYLHLAPEPELTKALIDNKVVSIAYETVQLDNRLLPLLAPMSEVAGRMSAQIGAQFLEKNKGGKGILLA
GVPGVKRGKVTIIGGGQAGTNAAKIAVGLGADVTIIDLSAERLRQLDDIFGNQVKTLMSNPYNIAEAVKESDLVIGAVLI
PGAKAPKLVTEEMIQSMEPGSVVVDIAIDQGGIFETTDRITTHDNPTYEKHGVVHYAVANMPGAVPRTSTLALTNVTVPY
AVQIANKGYKDACLGNTALLKGINTLDGYVTFEAVAEAHGLQYADAKELLEKAPALS

Sequences:

>Translated_377_residues
MRIGIPTEIKNNENRVAMTPAGAVHLVQNGHEVFVQKGAGLGSGFTDEEYVQAGAKLVETAEEAWNQDMVMKVKEPVASE
YGYFREGLILFTYLHLAPEPELTKALIDNKVVSIAYETVQLDNRLLPLLAPMSEVAGRMSAQIGAQFLEKNKGGKGILLA
GVPGVKRGKVTIIGGGQAGTNAAKIAVGLGADVTIIDLSAERLRQLDDIFGNQVKTLMSNPYNIAEAVKESDLVIGAVLI
PGAKAPKLVTEEMIQSMEPGSVVVDIAIDQGGIFETTDRITTHDNPTYEKHGVVHYAVANMPGAVPRTSTLALTNVTVPY
AVQIANKGYKDACLGNTALLKGINTLDGYVTFEAVAEAHGLQYADAKELLEKAPALS
>Mature_377_residues
MRIGIPTEIKNNENRVAMTPAGAVHLVQNGHEVFVQKGAGLGSGFTDEEYVQAGAKLVETAEEAWNQDMVMKVKEPVASE
YGYFREGLILFTYLHLAPEPELTKALIDNKVVSIAYETVQLDNRLLPLLAPMSEVAGRMSAQIGAQFLEKNKGGKGILLA
GVPGVKRGKVTIIGGGQAGTNAAKIAVGLGADVTIIDLSAERLRQLDDIFGNQVKTLMSNPYNIAEAVKESDLVIGAVLI
PGAKAPKLVTEEMIQSMEPGSVVVDIAIDQGGIFETTDRITTHDNPTYEKHGVVHYAVANMPGAVPRTSTLALTNVTVPY
AVQIANKGYKDACLGNTALLKGINTLDGYVTFEAVAEAHGLQYADAKELLEKAPALS

Specific function: This enzyme is a key factor in the assimilation of L- alanine as an energy source through the tricarboxylic acid cycle during sporulation [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=346, Percent_Identity=32.3699421965318, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI122939153, Length=346, Percent_Identity=32.3699421965318, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1787887, Length=334, Percent_Identity=33.8323353293413, Blast_Score=141, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17550456, Length=338, Percent_Identity=31.3609467455621, Blast_Score=151, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 40136; Mature: 40136

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00837 ALADH_PNT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGIPTEIKNNENRVAMTPAGAVHLVQNGHEVFVQKGAGLGSGFTDEEYVQAGAKLVET
CCCCCCCCCCCCCCEEEECCCCEEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
AEEAWNQDMVMKVKEPVASEYGYFREGLILFTYLHLAPEPELTKALIDNKVVSIAYETVQ
HHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCEEEEEEEEHH
LDNRLLPLLAPMSEVAGRMSAQIGAQFLEKNKGGKGILLAGVPGVKRGKVTIIGGGQAGT
HCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCCCCC
NAAKIAVGLGADVTIIDLSAERLRQLDDIFGNQVKTLMSNPYNIAEAVKESDLVIGAVLI
CCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEEEE
PGAKAPKLVTEEMIQSMEPGSVVVDIAIDQGGIFETTDRITTHDNPTYEKHGVVHYAVAN
CCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCEECCCCEECCCCCCHHHCCEEEEEECC
MPGAVPRTSTLALTNVTVPYAVQIANKGYKDACLGNTALLKGINTLDGYVTFEAVAEAHG
CCCCCCCCCEEEEEECCCCEEEEECCCCCCHHHCCCHHHHHCCHHHCCHHHHHHHHHHHC
LQYADAKELLEKAPALS
CCCCCHHHHHHHCCCCC
>Mature Secondary Structure
MRIGIPTEIKNNENRVAMTPAGAVHLVQNGHEVFVQKGAGLGSGFTDEEYVQAGAKLVET
CCCCCCCCCCCCCCEEEECCCCEEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
AEEAWNQDMVMKVKEPVASEYGYFREGLILFTYLHLAPEPELTKALIDNKVVSIAYETVQ
HHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCEEEEEEEEHH
LDNRLLPLLAPMSEVAGRMSAQIGAQFLEKNKGGKGILLAGVPGVKRGKVTIIGGGQAGT
HCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCCCCC
NAAKIAVGLGADVTIIDLSAERLRQLDDIFGNQVKTLMSNPYNIAEAVKESDLVIGAVLI
CCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEEEE
PGAKAPKLVTEEMIQSMEPGSVVVDIAIDQGGIFETTDRITTHDNPTYEKHGVVHYAVAN
CCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCEECCCCEECCCCCCHHHCCEEEEEECC
MPGAVPRTSTLALTNVTVPYAVQIANKGYKDACLGNTALLKGINTLDGYVTFEAVAEAHG
CCCCCCCCCEEEEEECCCCEEEEECCCCCCHHHCCCHHHHHCCHHHCCHHHHHHHHHHHC
LQYADAKELLEKAPALS
CCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2340274 [H]