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The map label for this gene is cidA1 [H]

Identifier: 218904802

GI number: 218904802

Start: 3521283

End: 3521648

Strand: Direct

Name: cidA1 [H]

Synonym: BCAH820_3686

Alternate gene names: 218904802

Gene position: 3521283-3521648 (Clockwise)

Preceding gene: 218904797

Following gene: 218904803

Centisome position: 66.41

GC content: 34.43

Gene sequence:

>366_bases
ATGAAATGGTGGAAATTAAGCGGACAAATTTTACTATTATTTTGTTTCGCTTGGACAGGTGAATGGATTACAAAACAGGC
ACACCTCCCAGTTCCAGGAAGTATTATCGGTATTTTTTTATTATTAATTTCGTTAAAATTTAACCTAGTGAAAAAAGAGT
GGATACAGGACGGTGCAGACTTTTTATTAAAAGAACTTATTTTATTTTTCATTCCTTCTGCAGTCGCTGTCATACGCTAC
AAAGATACACTATCACAATATGGAATCGATCTCATCTTAATTATTATGATTAGTACACTTTGTGTCACTCTCGTTACAGG
ACTCTTAACAGAATTGCTACTAAAGCGGAAAGGATCCGTGCAATGA

Upstream 100 bases:

>100_bases
TAATTTATATATTAGACAAATTTTTCGAATGAACGTATAGTAGAAATTGTTAATTCTTTTTTACAATTTTTATGTAAAAA
AAGAAAGAGGTGGTTACTGT

Downstream 100 bases:

>100_bases
TCGGCTTTCTTTGTTTACTATTAACACTATTCACATATTGGATATCGAAGAAAATGTATCAACGCTGGAATTGGAGCCTA
CTTTCTCCTCTTCTCGTCTG

Product: holin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 121

Protein sequence:

>121_residues
MKWWKLSGQILLLFCFAWTGEWITKQAHLPVPGSIIGIFLLLISLKFNLVKKEWIQDGADFLLKELILFFIPSAVAVIRY
KDTLSQYGIDLILIIMISTLCVTLVTGLLTELLLKRKGSVQ

Sequences:

>Translated_121_residues
MKWWKLSGQILLLFCFAWTGEWITKQAHLPVPGSIIGIFLLLISLKFNLVKKEWIQDGADFLLKELILFFIPSAVAVIRY
KDTLSQYGIDLILIIMISTLCVTLVTGLLTELLLKRKGSVQ
>Mature_121_residues
MKWWKLSGQILLLFCFAWTGEWITKQAHLPVPGSIIGIFLLLISLKFNLVKKEWIQDGADFLLKELILFFIPSAVAVIRY
KDTLSQYGIDLILIIMISTLCVTLVTGLLTELLLKRKGSVQ

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 13765; Mature: 13765

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWWKLSGQILLLFCFAWTGEWITKQAHLPVPGSIIGIFLLLISLKFNLVKKEWIQDGAD
CCCCCCCCHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLKELILFFIPSAVAVIRYKDTLSQYGIDLILIIMISTLCVTLVTGLLTELLLKRKGSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
Q
C
>Mature Secondary Structure
MKWWKLSGQILLLFCFAWTGEWITKQAHLPVPGSIIGIFLLLISLKFNLVKKEWIQDGAD
CCCCCCCCHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLKELILFFIPSAVAVIRYKDTLSQYGIDLILIIMISTLCVTLVTGLLTELLLKRKGSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]