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The map label for this gene is hblA [H]

Identifier: 218904261

GI number: 218904261

Start: 2979156

End: 2980283

Strand: Reverse

Name: hblA [H]

Synonym: BCAH820_3145

Alternate gene names: 218904261

Gene position: 2980283-2979156 (Counterclockwise)

Preceding gene: 218904262

Following gene: 218904260

Centisome position: 56.2

GC content: 33.78

Gene sequence:

>1128_bases
ATGATAAAAAAAATCCCTTACAAATTACTCGCTGTATCGACGCTATTAACTATTACAACTGCTAATGTAGTTTCACCAGT
AACAACTTTTGCAAGTGAAATTGAACAAACGAACAATGAAGATTCAGCTCTTTCTGCAAATGAAGCGAGAATGAAAGAGA
CCTTGCAAAAGGCTGGATTATTTGCAAAATCTATGAATGCCTATTCTTATATGTTAATTAAAAATCCGGATGTGAATTTT
GAGGGAATTACCATTAATGGATATGTAGATTTACCTGGTAGAATCGTACAAGATCAAAAGAATGCAAGAGCACATGCTGT
TACTTGGGATACGAAAGTAAAAAAACAGCTTTTAGATACATTGAATGGTATTGTTGAATACGATACAACATTTGACAATT
ATTATGAAACAATGGTAGAGGCGATTAATACAGGGGATGGAGAAACTTTAAAAGAAGGGATTACAGATTTGCGAGGTGAA
ATTCAACAAAATCAAAAGTATGCACAACAACTAATAGAAGAATTAACTAAATTAAGAGACTCTATTGGACACGATGTTAG
AGCATTTGGAAGTAATAAAGAGCTCTTGCAGTCAATTTTAAAAAATCAAGGTGCAGATGTTGATGCCGATCAAAAGCGTC
TAGAAGAAGTATTAGGATCAGTAAACTATTATAAACAATTAGAATCTGATGGGTTTAATGTAATGAAGGGTGCTATTTTG
GGTCTACCAATAATTGGCGGTATCATAGTGGGAGTAGCAAGAGATAATTTAGGTAAGTTAGAGCCTTTATTAGCAGAATT
ACGTCAGACCGTGGATTATAAAGTAACCTTAAATCGTGTAGTTGGAGTTGCTTACAGTAATATTAATGAAATGCACAAGG
CACTTGATGATGCTATTAACGCTCTTACTTATATGTCCACGCAGTGGCATGATTTAGATTCTCAATATTCGGGCGTTCTA
GGGCATATTGAGAATGCAGCTCAAAAAGCCGATCAAAATAAATTTAAATTCTTAAAACCTAATTTAAATGCAGCGAAAGA
CAGTTGGAAAACATTACGAACAGATGCTGTTACATTAAAAGAAGGAATAAAGGAGTTAAAAGTAGAAACTGTTACTCCAC
AAAAATAG

Upstream 100 bases:

>100_bases
TTGGAATGATATTCATAAAGATGCAGAATTCATTTCAAAAGATATTGCTTTTAAACAGGAGTAGAACTGAAATTTAAAAC
CTAAATTGGAGGAAAATGAA

Downstream 100 bases:

>100_bases
GGAAATATTAATTCTGTTGTAAAGTGAACTAAAACATAGAAAGTCTATGATTACACTGTTAAACAGAAAAGTGGTAATTA
ATAAATCCTTATATAACAGA

Product: hemolysin BL binding component B

Products: NA

Alternate protein names: Enterotoxin 40 kDa subunit [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MIKKIPYKLLAVSTLLTITTANVVSPVTTFASEIEQTNNEDSALSANEARMKETLQKAGLFAKSMNAYSYMLIKNPDVNF
EGITINGYVDLPGRIVQDQKNARAHAVTWDTKVKKQLLDTLNGIVEYDTTFDNYYETMVEAINTGDGETLKEGITDLRGE
IQQNQKYAQQLIEELTKLRDSIGHDVRAFGSNKELLQSILKNQGADVDADQKRLEEVLGSVNYYKQLESDGFNVMKGAIL
GLPIIGGIIVGVARDNLGKLEPLLAELRQTVDYKVTLNRVVGVAYSNINEMHKALDDAINALTYMSTQWHDLDSQYSGVL
GHIENAAQKADQNKFKFLKPNLNAAKDSWKTLRTDAVTLKEGIKELKVETVTPQK

Sequences:

>Translated_375_residues
MIKKIPYKLLAVSTLLTITTANVVSPVTTFASEIEQTNNEDSALSANEARMKETLQKAGLFAKSMNAYSYMLIKNPDVNF
EGITINGYVDLPGRIVQDQKNARAHAVTWDTKVKKQLLDTLNGIVEYDTTFDNYYETMVEAINTGDGETLKEGITDLRGE
IQQNQKYAQQLIEELTKLRDSIGHDVRAFGSNKELLQSILKNQGADVDADQKRLEEVLGSVNYYKQLESDGFNVMKGAIL
GLPIIGGIIVGVARDNLGKLEPLLAELRQTVDYKVTLNRVVGVAYSNINEMHKALDDAINALTYMSTQWHDLDSQYSGVL
GHIENAAQKADQNKFKFLKPNLNAAKDSWKTLRTDAVTLKEGIKELKVETVTPQK
>Mature_375_residues
MIKKIPYKLLAVSTLLTITTANVVSPVTTFASEIEQTNNEDSALSANEARMKETLQKAGLFAKSMNAYSYMLIKNPDVNF
EGITINGYVDLPGRIVQDQKNARAHAVTWDTKVKKQLLDTLNGIVEYDTTFDNYYETMVEAINTGDGETLKEGITDLRGE
IQQNQKYAQQLIEELTKLRDSIGHDVRAFGSNKELLQSILKNQGADVDADQKRLEEVLGSVNYYKQLESDGFNVMKGAIL
GLPIIGGIIVGVARDNLGKLEPLLAELRQTVDYKVTLNRVVGVAYSNINEMHKALDDAINALTYMSTQWHDLDSQYSGVL
GHIENAAQKADQNKFKFLKPNLNAAKDSWKTLRTDAVTLKEGIKELKVETVTPQK

Specific function: Cytotoxic protein, part of the enterotoxin complex. Responsible for binding to erythrocytes. This enterotoxin is thought to be the cause of the diarrheal form of gastroenteritis caused by food-borne strains of B.cereus [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008414
- InterPro:   IPR010356 [H]

Pfam domain/function: PF05791 Bacillus_HBL [H]

EC number: NA

Molecular weight: Translated: 41737; Mature: 41737

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKIPYKLLAVSTLLTITTANVVSPVTTFASEIEQTNNEDSALSANEARMKETLQKAGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
FAKSMNAYSYMLIKNPDVNFEGITINGYVDLPGRIVQDQKNARAHAVTWDTKVKKQLLDT
HHHCCCCEEEEEEECCCCCEEEEEEEEEECCCCHHHCCCCCCCEEEEECHHHHHHHHHHH
LNGIVEYDTTFDNYYETMVEAINTGDGETLKEGITDLRGEIQQNQKYAQQLIEELTKLRD
HHHHEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIGHDVRAFGSNKELLQSILKNQGADVDADQKRLEEVLGSVNYYKQLESDGFNVMKGAIL
HHCCHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GLPIIGGIIVGVARDNLGKLEPLLAELRQTVDYKVTLNRVVGVAYSNINEMHKALDDAIN
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHH
ALTYMSTQWHDLDSQYSGVLGHIENAAQKADQNKFKFLKPNLNAAKDSWKTLRTDAVTLK
HHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHH
EGIKELKVETVTPQK
HHHHHHEECCCCCCC
>Mature Secondary Structure
MIKKIPYKLLAVSTLLTITTANVVSPVTTFASEIEQTNNEDSALSANEARMKETLQKAGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
FAKSMNAYSYMLIKNPDVNFEGITINGYVDLPGRIVQDQKNARAHAVTWDTKVKKQLLDT
HHHCCCCEEEEEEECCCCCEEEEEEEEEECCCCHHHCCCCCCCEEEEECHHHHHHHHHHH
LNGIVEYDTTFDNYYETMVEAINTGDGETLKEGITDLRGEIQQNQKYAQQLIEELTKLRD
HHHHEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIGHDVRAFGSNKELLQSILKNQGADVDADQKRLEEVLGSVNYYKQLESDGFNVMKGAIL
HHCCHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GLPIIGGIIVGVARDNLGKLEPLLAELRQTVDYKVTLNRVVGVAYSNINEMHKALDDAIN
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHH
ALTYMSTQWHDLDSQYSGVLGHIENAAQKADQNKFKFLKPNLNAAKDSWKTLRTDAVTLK
HHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHH
EGIKELKVETVTPQK
HHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7693651; 8319899 [H]