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The map label for this gene is helD [H]

Identifier: 218903937

GI number: 218903937

Start: 2674645

End: 2676714

Strand: Reverse

Name: helD [H]

Synonym: BCAH820_2821

Alternate gene names: 218903937

Gene position: 2676714-2674645 (Counterclockwise)

Preceding gene: 218903939

Following gene: 218903936

Centisome position: 50.48

GC content: 34.83

Gene sequence:

>2070_bases
ATGAACAACATTTTTGAAGAAGAGTTACAAAAAATGAAAGATACATTACGTACGATGGATGATCAATTAGAACAGCTTGA
AAAAATCCCAGTTTATTATGGCGATGATTTTAAAGAGCAAATTCTTGAAAGTATGAGGGAGTCTAATAGACAAAACTTAC
GTATTGGTGTACAAGAACCGTACTTTGGAAGATTAGATTTTCAAGAGGATGGCAAGGAAGAAGTTATGCCGATCTACATC
GGTAAGGTAGGTGTTTCAGATAAAGATACGATGAAACCAATTGTAATTGATTGGCGGGCACCTGTCGCAAGTATGTTTTA
TTCATTTACCGGCGGTGATGAATTAGCGTTTTATCAATCACCAGACGGATTAGTAGAAGGTGATGTTTATTTAAAGCGAA
ACATCTCTATTCGAAAAAGAGAATTAGAACGTGTTGTTGATACATATGTAAAAGGAAATGAAGATGTCTCGCATGCCGAT
GATTTTCTTCTATATCGATTAGGTGAGAATAAAGATAATAAACTAAAGGATATTGTTTCGACGATACAATCGGAGCAAAA
TGATATTATTCGTGCGGAAAGAAACTTACCATTACTTATTCAAGGGGTTGCAGGAAGCGGTAAAACAACAATCGCTTTAC
ATCGCCTTGCTTTTTTAATTTATGAATATCGTGAGCAATTAGAAGCGGAGCGAATGATTGTTTTCGCTCCGAATAGTCTG
TTTTTAGACTATATTTCGAGTGTACTTCCTGAATTAGGTGTAGGGAATATTAGTCAAATAACATTTCTGGACTGGGCATT
ACGTACATTAGATGATTCGGTGAAACTGAAGCAGACAGAAGAAAAGTTGAAAGAAGCATTTTCTATTAATCGTGATGAAA
GAAAGGTTATGCTTGGTAAATTGAAAGGTACGCTAGAATTTAAGTCCTTTATTGAAGAGCAAATGGTTCAAATTGAAAAA
GAACTAGTACCAACAATTAATTTTGAGGCATGGGATAAAGCTGTTATTCCAGTGGAAGATATTAAAAAGTGGATGCAAGT
CGAATATAAACACTATCCATTAAAGAAAAGAAGAGAACGTCTAGTCGGCCGAATGAAACGCTGGATTGAAATTGAACTGA
AAAAGTATGAAGAAACAAACGAGAAAAAATTACTCAAAAAAGAAGCAACTAAAAGACTGAACACTTACATGAAGTTTTGG
CCGAAAATGAGTGCTCTTTCACTGTATAGTTCAATATTAAAGAGTAAGGAAATACTCGGAGTATTACCTGAAGAACTTGT
TAAAGAAACAGAAAAGAATTGTCGTAAAAAAGAAGTGTATGTAGAAGATTTACCTGCTTTAATATACATACATCACCGCA
TCACAGGTATTGAAATTGGACAAAAGTTTCATCACGTCGTTATCGATGAAGCGCAAGATTTCTCGCCATTCCAAGTTTAT
GTATTAAAAGAAATTACACTAGGTAACTCTTTCACTATATTAGGTGATTTATCTCAAGCGATTTATGATTATCAAGGGAT
TGAAGATTGGAGTGCGTTTAAGGAAGTATTCCAAGAAACAGGTTATTATGAACTGACGAGAAGTTATCGTTCTACAAAAG
AAATTATTGAATTCGCAAATGAGATAATAAAAAATGCAGAAATTCCTGTAGGGCTTGCAATGCCAGTTTTCCGTAGTGGA
GAAGAAGTAAAAGTAATTCATACAGAAGATCAGTTTACTGAAATTTTGAAGACATTAAAACAGCTACAAAATGCAGATGT
GAAAACAATTGCGGTAATCGGAAGAACAGACGATGAATGCCGCGATATGTATGAGAAATTAACGAATGCAGGATTGACTG
TAAACGTCATTGAAGCAGATCAAAGTAAATATGAAGGGGGCATTTCGGTAGTACCTGTATACTTAGCGAAAGGGTTAGAA
TTTGATGCTGCTCTACTCATTGATGTCGATGAAGAACATTATAAAAATACGAAACACGATGCGAAGTTATTATATGTCGG
ATGTACAAGGTCGCTTCATGATTTATGGATTTTCCATAGCGGGGAAGCATCTCCATTAATTAAGAAGTAA

Upstream 100 bases:

>100_bases
TTTTCAGAAAAAACAAATTAAGTCCTTGACTTTATAATTGGATTTTTAATACAATTATATTTCGACTGAAAAATTAGAAC
GGATAGGAGGGAATCATCTA

Downstream 100 bases:

>100_bases
AAATTCAAATGGTTTTTCAATAGAGAAGCATCTTATTTTATAAAAATATAGGGGACATGATAATGATTACAAAAGTAATA
ACAAAAAGAAATTGGGAAAT

Product: uvrD/Rep helicase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 689; Mature: 689

Protein sequence:

>689_residues
MNNIFEEELQKMKDTLRTMDDQLEQLEKIPVYYGDDFKEQILESMRESNRQNLRIGVQEPYFGRLDFQEDGKEEVMPIYI
GKVGVSDKDTMKPIVIDWRAPVASMFYSFTGGDELAFYQSPDGLVEGDVYLKRNISIRKRELERVVDTYVKGNEDVSHAD
DFLLYRLGENKDNKLKDIVSTIQSEQNDIIRAERNLPLLIQGVAGSGKTTIALHRLAFLIYEYREQLEAERMIVFAPNSL
FLDYISSVLPELGVGNISQITFLDWALRTLDDSVKLKQTEEKLKEAFSINRDERKVMLGKLKGTLEFKSFIEEQMVQIEK
ELVPTINFEAWDKAVIPVEDIKKWMQVEYKHYPLKKRRERLVGRMKRWIEIELKKYEETNEKKLLKKEATKRLNTYMKFW
PKMSALSLYSSILKSKEILGVLPEELVKETEKNCRKKEVYVEDLPALIYIHHRITGIEIGQKFHHVVIDEAQDFSPFQVY
VLKEITLGNSFTILGDLSQAIYDYQGIEDWSAFKEVFQETGYYELTRSYRSTKEIIEFANEIIKNAEIPVGLAMPVFRSG
EEVKVIHTEDQFTEILKTLKQLQNADVKTIAVIGRTDDECRDMYEKLTNAGLTVNVIEADQSKYEGGISVVPVYLAKGLE
FDAALLIDVDEEHYKNTKHDAKLLYVGCTRSLHDLWIFHSGEASPLIKK

Sequences:

>Translated_689_residues
MNNIFEEELQKMKDTLRTMDDQLEQLEKIPVYYGDDFKEQILESMRESNRQNLRIGVQEPYFGRLDFQEDGKEEVMPIYI
GKVGVSDKDTMKPIVIDWRAPVASMFYSFTGGDELAFYQSPDGLVEGDVYLKRNISIRKRELERVVDTYVKGNEDVSHAD
DFLLYRLGENKDNKLKDIVSTIQSEQNDIIRAERNLPLLIQGVAGSGKTTIALHRLAFLIYEYREQLEAERMIVFAPNSL
FLDYISSVLPELGVGNISQITFLDWALRTLDDSVKLKQTEEKLKEAFSINRDERKVMLGKLKGTLEFKSFIEEQMVQIEK
ELVPTINFEAWDKAVIPVEDIKKWMQVEYKHYPLKKRRERLVGRMKRWIEIELKKYEETNEKKLLKKEATKRLNTYMKFW
PKMSALSLYSSILKSKEILGVLPEELVKETEKNCRKKEVYVEDLPALIYIHHRITGIEIGQKFHHVVIDEAQDFSPFQVY
VLKEITLGNSFTILGDLSQAIYDYQGIEDWSAFKEVFQETGYYELTRSYRSTKEIIEFANEIIKNAEIPVGLAMPVFRSG
EEVKVIHTEDQFTEILKTLKQLQNADVKTIAVIGRTDDECRDMYEKLTNAGLTVNVIEADQSKYEGGISVVPVYLAKGLE
FDAALLIDVDEEHYKNTKHDAKLLYVGCTRSLHDLWIFHSGEASPLIKK
>Mature_689_residues
MNNIFEEELQKMKDTLRTMDDQLEQLEKIPVYYGDDFKEQILESMRESNRQNLRIGVQEPYFGRLDFQEDGKEEVMPIYI
GKVGVSDKDTMKPIVIDWRAPVASMFYSFTGGDELAFYQSPDGLVEGDVYLKRNISIRKRELERVVDTYVKGNEDVSHAD
DFLLYRLGENKDNKLKDIVSTIQSEQNDIIRAERNLPLLIQGVAGSGKTTIALHRLAFLIYEYREQLEAERMIVFAPNSL
FLDYISSVLPELGVGNISQITFLDWALRTLDDSVKLKQTEEKLKEAFSINRDERKVMLGKLKGTLEFKSFIEEQMVQIEK
ELVPTINFEAWDKAVIPVEDIKKWMQVEYKHYPLKKRRERLVGRMKRWIEIELKKYEETNEKKLLKKEATKRLNTYMKFW
PKMSALSLYSSILKSKEILGVLPEELVKETEKNCRKKEVYVEDLPALIYIHHRITGIEIGQKFHHVVIDEAQDFSPFQVY
VLKEITLGNSFTILGDLSQAIYDYQGIEDWSAFKEVFQETGYYELTRSYRSTKEIIEFANEIIKNAEIPVGLAMPVFRSG
EEVKVIHTEDQFTEILKTLKQLQNADVKTIAVIGRTDDECRDMYEKLTNAGLTVNVIEADQSKYEGGISVVPVYLAKGLE
FDAALLIDVDEEHYKNTKHDAKLLYVGCTRSLHDLWIFHSGEASPLIKK

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 79969; Mature: 79969

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIFEEELQKMKDTLRTMDDQLEQLEKIPVYYGDDFKEQILESMRESNRQNLRIGVQEP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHCCCCCEEEECCCC
YFGRLDFQEDGKEEVMPIYIGKVGVSDKDTMKPIVIDWRAPVASMFYSFTGGDELAFYQS
CCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEECCCCHHHHHHHCCCCCEEEEEEC
PDGLVEGDVYLKRNISIRKRELERVVDTYVKGNEDVSHADDFLLYRLGENKDNKLKDIVS
CCCCEECCEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHCEEEEEECCCCCHHHHHHHH
TIQSEQNDIIRAERNLPLLIQGVAGSGKTTIALHRLAFLIYEYREQLEAERMIVFAPNSL
HHHCCCCCCEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHH
FLDYISSVLPELGVGNISQITFLDWALRTLDDSVKLKQTEEKLKEAFSINRDERKVMLGK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
LKGTLEFKSFIEEQMVQIEKELVPTINFEAWDKAVIPVEDIKKWMQVEYKHYPLKKRRER
HHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
LVGRMKRWIEIELKKYEETNEKKLLKKEATKRLNTYMKFWPKMSALSLYSSILKSKEILG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VLPEELVKETEKNCRKKEVYVEDLPALIYIHHRITGIEIGQKFHHVVIDEAQDFSPFQVY
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHCCHHHHHHHHHHHEECCCCCCCCEEEE
VLKEITLGNSFTILGDLSQAIYDYQGIEDWSAFKEVFQETGYYELTRSYRSTKEIIEFAN
EEEEEECCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
EIIKNAEIPVGLAMPVFRSGEEVKVIHTEDQFTEILKTLKQLQNADVKTIAVIGRTDDEC
HHHHCCCCCCCEECHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHH
RDMYEKLTNAGLTVNVIEADQSKYEGGISVVPVYLAKGLEFDAALLIDVDEEHYKNTKHD
HHHHHHHHCCCCEEEEEECCCHHHCCCCEEEHHHHHCCCCCCEEEEEECCHHHCCCCCCC
AKLLYVGCTRSLHDLWIFHSGEASPLIKK
CEEEEEECCCCHHHEEEEECCCCCCCCCC
>Mature Secondary Structure
MNNIFEEELQKMKDTLRTMDDQLEQLEKIPVYYGDDFKEQILESMRESNRQNLRIGVQEP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHCCCCCEEEECCCC
YFGRLDFQEDGKEEVMPIYIGKVGVSDKDTMKPIVIDWRAPVASMFYSFTGGDELAFYQS
CCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEECCCCHHHHHHHCCCCCEEEEEEC
PDGLVEGDVYLKRNISIRKRELERVVDTYVKGNEDVSHADDFLLYRLGENKDNKLKDIVS
CCCCEECCEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHCEEEEEECCCCCHHHHHHHH
TIQSEQNDIIRAERNLPLLIQGVAGSGKTTIALHRLAFLIYEYREQLEAERMIVFAPNSL
HHHCCCCCCEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHH
FLDYISSVLPELGVGNISQITFLDWALRTLDDSVKLKQTEEKLKEAFSINRDERKVMLGK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
LKGTLEFKSFIEEQMVQIEKELVPTINFEAWDKAVIPVEDIKKWMQVEYKHYPLKKRRER
HHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
LVGRMKRWIEIELKKYEETNEKKLLKKEATKRLNTYMKFWPKMSALSLYSSILKSKEILG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VLPEELVKETEKNCRKKEVYVEDLPALIYIHHRITGIEIGQKFHHVVIDEAQDFSPFQVY
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHCCHHHHHHHHHHHEECCCCCCCCEEEE
VLKEITLGNSFTILGDLSQAIYDYQGIEDWSAFKEVFQETGYYELTRSYRSTKEIIEFAN
EEEEEECCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
EIIKNAEIPVGLAMPVFRSGEEVKVIHTEDQFTEILKTLKQLQNADVKTIAVIGRTDDEC
HHHHCCCCCCCEECHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHH
RDMYEKLTNAGLTVNVIEADQSKYEGGISVVPVYLAKGLEFDAALLIDVDEEHYKNTKHD
HHHHHHHHCCCCEEEEEECCCHHHCCCCEEEHHHHHCCCCCCEEEEEECCHHHCCCCCCC
AKLLYVGCTRSLHDLWIFHSGEASPLIKK
CEEEEEECCCCHHHEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]