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The map label for this gene is narA1 [H]

Identifier: 218903282

GI number: 218903282

Start: 2051905

End: 2052918

Strand: Direct

Name: narA1 [H]

Synonym: BCAH820_2166

Alternate gene names: 218903282

Gene position: 2051905-2052918 (Clockwise)

Preceding gene: 218903280

Following gene: 218903283

Centisome position: 38.7

GC content: 35.31

Gene sequence:

>1014_bases
ATGCACGAGAAAATGAAAGATTCTTTAGAACGGCCACTTCAAGATTTACGTATTTCAGTTATTGATCGTTGTAATTTTAG
GTGCACATACTGTATGCCTGCTGAAGTATTTGGACCTGATTACGCTTTTTTACAGGAAGAGTTTTTATTAACTTTTGATG
AAATAGAAAGATTAGCTAGATTATTTATAAGAATGGGAGTCAATAAAATTAGGCTTACAGGCGGTGAACCGTTATTGCGT
AAAGACTTACCGCATTTAATTGCAAGGCTTGCAAAGCTAGATGGTTTAAAAGATATTGGGCTCACAACAAATGGAATTCA
TTTAGCAAAACAAGCTAAGGCGCTAAAAGAAGCAGGATTAAAGCGTGTAAATATTAGTTTAGATGCAATAGAGGATCGTG
TCTTCCAAAAAATTAATGGAAGACATGTAAGTACGAAACCTGTACTGAAAGGAATTGAAGCAGCGAAGGAAGCTGGATTA
GAAGTAAAGGTAAATATGGTCGTAAAAAAAGGGATGAATGATAGTCAAATTCTTCCTATGGCTCAGTATTTTAAAGAACA
AGAAATACAGTTACGTTTCATTGAGTTTATGGATGTAGGCAGTACGAACGGATGGAACTTTGAACAAGTCGTTACGAAGG
AACAATTAATAGAGAAAATTAATCGTGTATATCCAATTGAACCTGTTAAACCTCGTTACTTTGGAGAAGTTGCGAAATTG
TATCGATATGTAGGAAACGATGCTGAAGTTGGATTTATTACTTCAGTATCTGAGTCATTTTGTTCTTCTTGTACGAGAGC
ACGTATTTCGGCAGACGGCAAGTTTTATACGTGCTTATTTGGAGAAAAAGGAACGGATTTACGATCGCTTCTTCGAGAAA
ATATTTCTGATGCATCACTATTAAAAATTTTACAACATACATGGCGATATAGAACAGATCGATATTCAGATGAAAGAACG
GCGGAAAGTACAAATAAACGTCAAAAAGTTGAGATGTCTTACATTGGTGGATAG

Upstream 100 bases:

>100_bases
TGAGAAAAGTCACATTGAATATGTAGCTTCTTTTTTATAATGAAGGCAAATAAAAAAATGAAAGCTTACTAAGGATTGCA
ACAGAAAAGAAGGGATATAG

Downstream 100 bases:

>100_bases
CGAAAGGAGGATTCCTTATGCAAGAGCGATATTCAAGACAAGTATTGTTTTCTGGAATAGGTGAAATGGGACAAAGGAAA
ATAAGGGAAAAGCATGTGCT

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MHEKMKDSLERPLQDLRISVIDRCNFRCTYCMPAEVFGPDYAFLQEEFLLTFDEIERLARLFIRMGVNKIRLTGGEPLLR
KDLPHLIARLAKLDGLKDIGLTTNGIHLAKQAKALKEAGLKRVNISLDAIEDRVFQKINGRHVSTKPVLKGIEAAKEAGL
EVKVNMVVKKGMNDSQILPMAQYFKEQEIQLRFIEFMDVGSTNGWNFEQVVTKEQLIEKINRVYPIEPVKPRYFGEVAKL
YRYVGNDAEVGFITSVSESFCSSCTRARISADGKFYTCLFGEKGTDLRSLLRENISDASLLKILQHTWRYRTDRYSDERT
AESTNKRQKVEMSYIGG

Sequences:

>Translated_337_residues
MHEKMKDSLERPLQDLRISVIDRCNFRCTYCMPAEVFGPDYAFLQEEFLLTFDEIERLARLFIRMGVNKIRLTGGEPLLR
KDLPHLIARLAKLDGLKDIGLTTNGIHLAKQAKALKEAGLKRVNISLDAIEDRVFQKINGRHVSTKPVLKGIEAAKEAGL
EVKVNMVVKKGMNDSQILPMAQYFKEQEIQLRFIEFMDVGSTNGWNFEQVVTKEQLIEKINRVYPIEPVKPRYFGEVAKL
YRYVGNDAEVGFITSVSESFCSSCTRARISADGKFYTCLFGEKGTDLRSLLRENISDASLLKILQHTWRYRTDRYSDERT
AESTNKRQKVEMSYIGG
>Mature_337_residues
MHEKMKDSLERPLQDLRISVIDRCNFRCTYCMPAEVFGPDYAFLQEEFLLTFDEIERLARLFIRMGVNKIRLTGGEPLLR
KDLPHLIARLAKLDGLKDIGLTTNGIHLAKQAKALKEAGLKRVNISLDAIEDRVFQKINGRHVSTKPVLKGIEAAKEAGL
EVKVNMVVKKGMNDSQILPMAQYFKEQEIQLRFIEFMDVGSTNGWNFEQVVTKEQLIEKINRVYPIEPVKPRYFGEVAKL
YRYVGNDAEVGFITSVSESFCSSCTRARISADGKFYTCLFGEKGTDLRSLLRENISDASLLKILQHTWRYRTDRYSDERT
AESTNKRQKVEMSYIGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI116734668, Length=301, Percent_Identity=41.1960132890365, Blast_Score=225, Evalue=4e-59,
Organism=Homo sapiens, GI22027536, Length=301, Percent_Identity=41.1960132890365, Blast_Score=225, Evalue=6e-59,
Organism=Escherichia coli, GI1786999, Length=338, Percent_Identity=34.6153846153846, Blast_Score=205, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI32566331, Length=322, Percent_Identity=34.7826086956522, Blast_Score=195, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI32566329, Length=323, Percent_Identity=34.6749226006192, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17561210, Length=323, Percent_Identity=35.2941176470588, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI28574490, Length=314, Percent_Identity=37.2611464968153, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI28574488, Length=304, Percent_Identity=38.1578947368421, Blast_Score=208, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR000385
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 38620; Mature: 38620

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEKMKDSLERPLQDLRISVIDRCNFRCTYCMPAEVFGPDYAFLQEEFLLTFDEIERLAR
CCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHH
LFIRMGVNKIRLTGGEPLLRKDLPHLIARLAKLDGLKDIGLTTNGIHLAKQAKALKEAGL
HHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCC
KRVNISLDAIEDRVFQKINGRHVSTKPVLKGIEAAKEAGLEVKVNMVVKKGMNDSQILPM
EEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCHH
AQYFKEQEIQLRFIEFMDVGSTNGWNFEQVVTKEQLIEKINRVYPIEPVKPRYFGEVAKL
HHHHHHHHHHHHEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
YRYVGNDAEVGFITSVSESFCSSCTRARISADGKFYTCLFGEKGTDLRSLLRENISDASL
HHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCHHHH
LKILQHTWRYRTDRYSDERTAESTNKRQKVEMSYIGG
HHHHHHHHHHHCCCCCCHHHHHHCCHHHEEEEHCCCC
>Mature Secondary Structure
MHEKMKDSLERPLQDLRISVIDRCNFRCTYCMPAEVFGPDYAFLQEEFLLTFDEIERLAR
CCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHH
LFIRMGVNKIRLTGGEPLLRKDLPHLIARLAKLDGLKDIGLTTNGIHLAKQAKALKEAGL
HHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCC
KRVNISLDAIEDRVFQKINGRHVSTKPVLKGIEAAKEAGLEVKVNMVVKKGMNDSQILPM
EEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCCCCHH
AQYFKEQEIQLRFIEFMDVGSTNGWNFEQVVTKEQLIEKINRVYPIEPVKPRYFGEVAKL
HHHHHHHHHHHHEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
YRYVGNDAEVGFITSVSESFCSSCTRARISADGKFYTCLFGEKGTDLRSLLRENISDASL
HHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCHHHH
LKILQHTWRYRTDRYSDERTAESTNKRQKVEMSYIGG
HHHHHHHHHHHCCCCCCHHHHHHCCHHHEEEEHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA