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The map label for this gene is fabH2 [H]

Identifier: 218902987

GI number: 218902987

Start: 1768724

End: 1769707

Strand: Reverse

Name: fabH2 [H]

Synonym: BCAH820_1870

Alternate gene names: 218902987

Gene position: 1769707-1768724 (Counterclockwise)

Preceding gene: 218902990

Following gene: 218902983

Centisome position: 33.37

GC content: 36.69

Gene sequence:

>984_bases
ATGAATTCTAAATCCCGTATTACTGCAATTGGTACTCATGTTCCAAATCAAATACTCTCTAATCATGATTTAGAAAAAAT
GATTGATACAAATGATGAATGGATTGTACAAAGAACAGGAATGAAGGAAAGAAGAATTGCTAGCGAAGATGAATACTCCT
CACACTTAGCCATTAAAGCCATTGAAAATTTATGTACAACATTTAAAAAGAACTTAGAAGATATCGACTGTATCATCGTC
GCTACAACGACTGCTGACTTTGTTTTTCCTAGTGTCGCGTGTCAAATACAACAACACTTCAACATACCTCATACAATGGC
ATTTGATTTAAATGCAACTTGCGCTGGTTTCACATATGGCTTGCACGTCGGTAATAGCTTGATTACTTCTGGATCACATA
AAAAAGTACTTGTCGTAGCGACAGAGACATTATCAAAAGTTACTGATTACACCGATAGAACGACCTGCATTTTATTCGGT
GATGGTGCTGGTGCTATTTTATTAGAAAGAGATGAAAACAAACCAAGCTTTATCGCGTATCATATGGGCACAAATGGGCA
CGGCGGTATTCATCTATACAGAACAAACTTATCTACTACTATGAATGACACTCCACTGCAAACAAATGAAAAAATCGTTC
AAAATGGGAGAGAAGTATATAAATGGGCAACACGCACAGTGCCAGTAGGTATAAAAGAACTGTTACATACTGCAAATATG
AAAATGGATGATATAGACTGGTTCATTCCTCATAGCGCTAACTTACGCATGATTGAATCTATTTGTGAAAAATCTCAAAT
TCCAATACACAAAACATTAACGAGCGTGGAATATATGGGGAATACCTCTTCTGTCTCTATTCCACTCGCTCTAGATTTAG
CTAGAAAAGAAGGGAAATTAAATAACGGAGACACACTTTTACTGTACGGATTTGGCGGTGGTCTTACACATTTAGGCCTT
ATTGTGGAGTGGGATTTAAGCTAA

Upstream 100 bases:

>100_bases
AGTTAAGCATTCTAGTTTCAATAAAATAAAAGTCTTTATTGACATTTTTATAACCTAGTATTAGTATCAGGTTATAAAAA
TAAAGTTAGGAGCTGTTCCT

Downstream 100 bases:

>100_bases
ACATATAAAAAAGAGGTTCTAGTTAGTAACTAGAACCTCACTTCAATTTCGTTACCCTTTTCGGGACCATATCACAACAG
GGATAAGCATGAAAGCTAAT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III protein 2; Beta-ketoacyl-ACP synthase III 2; KAS III 2 [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MNSKSRITAIGTHVPNQILSNHDLEKMIDTNDEWIVQRTGMKERRIASEDEYSSHLAIKAIENLCTTFKKNLEDIDCIIV
ATTTADFVFPSVACQIQQHFNIPHTMAFDLNATCAGFTYGLHVGNSLITSGSHKKVLVVATETLSKVTDYTDRTTCILFG
DGAGAILLERDENKPSFIAYHMGTNGHGGIHLYRTNLSTTMNDTPLQTNEKIVQNGREVYKWATRTVPVGIKELLHTANM
KMDDIDWFIPHSANLRMIESICEKSQIPIHKTLTSVEYMGNTSSVSIPLALDLARKEGKLNNGDTLLLYGFGGGLTHLGL
IVEWDLS

Sequences:

>Translated_327_residues
MNSKSRITAIGTHVPNQILSNHDLEKMIDTNDEWIVQRTGMKERRIASEDEYSSHLAIKAIENLCTTFKKNLEDIDCIIV
ATTTADFVFPSVACQIQQHFNIPHTMAFDLNATCAGFTYGLHVGNSLITSGSHKKVLVVATETLSKVTDYTDRTTCILFG
DGAGAILLERDENKPSFIAYHMGTNGHGGIHLYRTNLSTTMNDTPLQTNEKIVQNGREVYKWATRTVPVGIKELLHTANM
KMDDIDWFIPHSANLRMIESICEKSQIPIHKTLTSVEYMGNTSSVSIPLALDLARKEGKLNNGDTLLLYGFGGGLTHLGL
IVEWDLS
>Mature_327_residues
MNSKSRITAIGTHVPNQILSNHDLEKMIDTNDEWIVQRTGMKERRIASEDEYSSHLAIKAIENLCTTFKKNLEDIDCIIV
ATTTADFVFPSVACQIQQHFNIPHTMAFDLNATCAGFTYGLHVGNSLITSGSHKKVLVVATETLSKVTDYTDRTTCILFG
DGAGAILLERDENKPSFIAYHMGTNGHGGIHLYRTNLSTTMNDTPLQTNEKIVQNGREVYKWATRTVPVGIKELLHTANM
KMDDIDWFIPHSANLRMIESICEKSQIPIHKTLTSVEYMGNTSSVSIPLALDLARKEGKLNNGDTLLLYGFGGGLTHLGL
IVEWDLS

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=312, Percent_Identity=38.7820512820513, Blast_Score=230, Evalue=9e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 36298; Mature: 36298

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSKSRITAIGTHVPNQILSNHDLEKMIDTNDEWIVQRTGMKERRIASEDEYSSHLAIKA
CCCCCEEEEEECCCCHHHHCCCCHHHHHCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHH
IENLCTTFKKNLEDIDCIIVATTTADFVFPSVACQIQQHFNIPHTMAFDLNATCAGFTYG
HHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEE
LHVGNSLITSGSHKKVLVVATETLSKVTDYTDRTTCILFGDGAGAILLERDENKPSFIAY
EECCCHHEECCCCCEEEEEEEHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCEEEE
HMGTNGHGGIHLYRTNLSTTMNDTPLQTNEKIVQNGREVYKWATRTVPVGIKELLHTANM
ECCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCHHHHHHHHCCCCCCHHHHHHHCCC
KMDDIDWFIPHSANLRMIESICEKSQIPIHKTLTSVEYMGNTSSVSIPLALDLARKEGKL
CCCCCEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEEEEHHHCCCC
NNGDTLLLYGFGGGLTHLGLIVEWDLS
CCCCEEEEEECCCCCCEEEEEEEEECC
>Mature Secondary Structure
MNSKSRITAIGTHVPNQILSNHDLEKMIDTNDEWIVQRTGMKERRIASEDEYSSHLAIKA
CCCCCEEEEEECCCCHHHHCCCCHHHHHCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHH
IENLCTTFKKNLEDIDCIIVATTTADFVFPSVACQIQQHFNIPHTMAFDLNATCAGFTYG
HHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEE
LHVGNSLITSGSHKKVLVVATETLSKVTDYTDRTTCILFGDGAGAILLERDENKPSFIAY
EECCCHHEECCCCCEEEEEEEHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCEEEE
HMGTNGHGGIHLYRTNLSTTMNDTPLQTNEKIVQNGREVYKWATRTVPVGIKELLHTANM
ECCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHCCHHHHHHHHCCCCCCHHHHHHHCCC
KMDDIDWFIPHSANLRMIESICEKSQIPIHKTLTSVEYMGNTSSVSIPLALDLARKEGKL
CCCCCEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEEEEHHHCCCC
NNGDTLLLYGFGGGLTHLGLIVEWDLS
CCCCEEEEEECCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]