Click here to switch to the map view.

The map label for this gene is trpB

Identifier: 218902439

GI number: 218902439

Start: 1258917

End: 1260038

Strand: Direct

Name: trpB

Synonym: BCAH820_1321

Alternate gene names: 218902439

Gene position: 1258917-1260038 (Clockwise)

Preceding gene: 218902438

Following gene: 218902440

Centisome position: 23.74

GC content: 41.89

Gene sequence:

>1122_bases
ATGCAATCTGTATTAGAACTAGAAGAAGCATATAAAGAGGCGATGGAAGATGAAGCATTTCAAAAGGAATTAAATCATTA
TTTAAAAACGTATGTCGGAAGAGAAACACCGCTTTATTTCGCTGAGAATATGACGGAGTATTGCGGAGGTGCAAAGATTT
ATTTAAAACGTGAAGATTTGAACCATACAGGAGCTCATAAAATTAACAATACAATTGGTCAGGCACTTCTTGCGGTGCGA
ATGGGCAAGAAAAAAGTTGTCGCTGAAACAGGGGCTGGACAACACGGTGTTGCAACAGCTACGGTATGTGCCCTTCTCGG
TTTAGAGTGCGTCATCTTTATGGGAGAAGAAGATGTGAGACGTCAAAAATTAAATGTGTTTCGAATGGAATTACTCGGAG
CGAAAGTAGAAAGTGTAGCGGCAGGTAGCGGTACATTAAAAGATGCGGTAAACGAGGCGCTTCGTTACTGGGTTTCACAC
GTGCATGATACGCACTACATTATGGGATCTGTTCTCGGACCGCATCCATTCCCGCAAATTGTCCGTGATTTCCAAAGTGT
AATTGGGAATGAGACGAAAAAACAATATGAAGCGTTAGAAGGAAAGTTACCAGAAGCAGTCGTTGCTTGCATTGGTGGTG
GGAGTAACGCAATGGGAATGTTTTATCCGTTTGTACATGATGAAGAAGTTGCTCTTTACGGCGTAGAAGCAGCTGGAAAA
GGTGTTCATACAGAAAAGCATGCAGCAACTTTAACGAAAGGAAGCGTCGGTGTTTTACACGGATCAATGATGTATCTTCT
GCAAAATGAAGAAGGTCAAATTCAAGAAGCGCACTCTATTTCAGCAGGGCTTGATTACCCAGGTGTTGGTCCAGAACATA
GCTTGCTCAAAGATATTGGCCGCGTTTCTTATCATTCCATTACTGATGATGAAGCGTTAGAAGCGTTTCAATTATTAACG
AAAAAAGAAGGGATTATCCCGGCGCTAGAAAGCTCGCATGCTGTCGCATACGCATTAAAATTAGCGCCGCAAATGAAGGA
AGATGAAGGACTTGTCATTTGTTTATCCGGCCGTGGTGATAAAGATGTAGAGAGTATAAAACGTTATATGGAAGAGGTGT
AA

Upstream 100 bases:

>100_bases
TATTATAAAAGCGAAGGAGTGTTCTAAATGAACTACGCATATCCCAGATGAAAAAGGTCACTACGGTATATACGGAGGAC
GATACGTTCCAGAAACGTTA

Downstream 100 bases:

>100_bases
AAAATGGGAGTAGAAAGAATTAAAGCAGCATTTGAAAATGGTAAGAAAGCATTTATTCCGTACGTAATGGGCGGAGATGG
TGGCCTTGAAATATTAAAAG

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MQSVLELEEAYKEAMEDEAFQKELNHYLKTYVGRETPLYFAENMTEYCGGAKIYLKREDLNHTGAHKINNTIGQALLAVR
MGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKVESVAAGSGTLKDAVNEALRYWVSH
VHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSNAMGMFYPFVHDEEVALYGVEAAGK
GVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDDEALEAFQLLT
KKEGIIPALESSHAVAYALKLAPQMKEDEGLVICLSGRGDKDVESIKRYMEEV

Sequences:

>Translated_373_residues
MQSVLELEEAYKEAMEDEAFQKELNHYLKTYVGRETPLYFAENMTEYCGGAKIYLKREDLNHTGAHKINNTIGQALLAVR
MGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKVESVAAGSGTLKDAVNEALRYWVSH
VHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSNAMGMFYPFVHDEEVALYGVEAAGK
GVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDDEALEAFQLLT
KKEGIIPALESSHAVAYALKLAPQMKEDEGLVICLSGRGDKDVESIKRYMEEV
>Mature_373_residues
MQSVLELEEAYKEAMEDEAFQKELNHYLKTYVGRETPLYFAENMTEYCGGAKIYLKREDLNHTGAHKINNTIGQALLAVR
MGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKVESVAAGSGTLKDAVNEALRYWVSH
VHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSNAMGMFYPFVHDEEVALYGVEAAGK
GVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDDEALEAFQLLT
KKEGIIPALESSHAVAYALKLAPQMKEDEGLVICLSGRGDKDVESIKRYMEEV

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family

Homologues:

Organism=Escherichia coli, GI1787515, Length=367, Percent_Identity=55.3133514986376, Blast_Score=406, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6321412, Length=369, Percent_Identity=58.8075880758808, Blast_Score=457, Evalue=1e-129,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPB_BACAA (C3P3U0)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002865769.1
- ProteinModelPortal:   C3P3U0
- SMR:   C3P3U0
- EnsemblBacteria:   EBBACT00000128173
- GeneID:   7849830
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_1329
- GeneTree:   EBGT00050000001631
- ProtClustDB:   PRK04346
- HAMAP:   MF_00133
- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026
- TIGRFAMs:   TIGR00263

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.2.1.20

Molecular weight: Translated: 40814; Mature: 40814

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSVLELEEAYKEAMEDEAFQKELNHYLKTYVGRETPLYFAENMTEYCGGAKIYLKREDL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCC
NHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVR
CCCCHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCHHHHHHHHHHHHHEEEEECCHHHH
RQKLNVFRMELLGAKVESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQI
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHH
VRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSNAMGMFYPFVHDEEVALYGVEAAGK
HHHHHHHHCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEEECCCCCCCEEEEEEHHCCC
GVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLLKDIG
CCCCHHHHHHHCCCCHHHHHHHEEEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHH
RVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKEDEGLVICLSGRGD
HHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCC
KDVESIKRYMEEV
CCHHHHHHHHHHC
>Mature Secondary Structure
MQSVLELEEAYKEAMEDEAFQKELNHYLKTYVGRETPLYFAENMTEYCGGAKIYLKREDL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCC
NHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVR
CCCCHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCHHHHHHHHHHHHHEEEEECCHHHH
RQKLNVFRMELLGAKVESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQI
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCHHHH
VRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSNAMGMFYPFVHDEEVALYGVEAAGK
HHHHHHHHCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEEECCCCCCCEEEEEEHHCCC
GVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLLKDIG
CCCCHHHHHHHCCCCHHHHHHHEEEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHH
RVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKEDEGLVICLSGRGD
HHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCCC
KDVESIKRYMEEV
CCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA