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The map label for this gene is glpD [H]

Identifier: 218902225

GI number: 218902225

Start: 1059336

End: 1061018

Strand: Direct

Name: glpD [H]

Synonym: BCAH820_1107

Alternate gene names: 218902225

Gene position: 1059336-1061018 (Clockwise)

Preceding gene: 218902224

Following gene: 218902227

Centisome position: 19.98

GC content: 40.52

Gene sequence:

>1683_bases
ATGAAATTTTCAAGTAAACAACGTAAAGACGTATTAAACGGAGTAAATAAACAAGAATTAGATGTGATCGTAATTGGTGG
AGGTATTACTGGTTCTGGTATTGCATTAGATGGAGCAACACGCGGGTTATCAACAATTGTGTTTGAAATGCAGGACTTTG
CAGCAGGTACATCAAGTCGTTCAACGAAGCTTGTACACGGTGGTCTACGTTATTTAAAACAACTTGAAGTGAAAATGGTA
GCAGAGGTGGGTAAAGAGCGTGCGATCGTATATGAGAACGGTCCCCATGTAACAACACCAGAGTGGATGTTACTTCCGTT
CCATACAGGAGGTACGTTCGGATCATTTAGTACATCAATTGGTCTTCGTGTATACGACTTCTTAGCAGGTGTAAAACGAA
GTGAGCGCAGAAAAATGTTTAACCGTGAAGAAACGCTGAAGAAAGAGCCTCTTGTAAAACAAGAAGGATTAAAAGGCGGC
GGTTACTACGTAGAATATCGTACAGACGATGCGCGTCTTACAATTGAAGTAATGAAAGAAGCAATTGAGCACGGCGCAAA
AGCTGTTAACTACGCAAAAGTAGACGGTTTCTTATATAAAGATGGAAAAGTATGTGGTGTACGTGTAATCGATTTACTAG
ACGGAGAAGTATACGAAGTTTACGGTAAGAAAATTGTAAACGCAGCTGGCCCTTGGGTAGATACACTTCGTGAAAAAGAT
AACTCGAAAAAAGGAAAAGTACTTCAGTTATCAAAAGGTGTTCACTTAGTAATTGATCAAAAACGTTTCCCATTAGGTCA
AGCGATTTACTTCGATACACCAGATAAACGTATGGTATTCGCGATTCCGCGCGGAGGAAAAACATATGTAGGTACAACAG
ATACGTTCTATGATAAAGACGCAGCTGTACCACAAATGACAACAGAAGATCGCACATACATTATTAATGCGATTAACTAC
ATGTTCCCAAGCGTAAAAATTACGGAAAAAGACATCGAATCAAGCTGGGCTGGTGTACGTCCGTTAATTTACGAAGAAGG
TAAGAGTGCATCTGAAATTTCTCGTAAAGATGAAATTTGGACTTCTGAATCTGGTTTAATTACAATCGCAGGTGGTAAAT
TAACAGGATACCGCAAAATGGCTGAAATGGTAGTAGACTACGTAACGAACTTGCTACAAAAAGAAGGTCATAGTGCATAT
CCGAAGAGCTCAACGAAACATATGCCAATCTCTGGTGGACATGTAGATGGCTCTAAAGGATTACCAGCATTTATCGCGAA
AAAAGCAGGCGAAGGTACGAAATACGGTTTAACAACAGCACAAGCAGAAGAATTCGCGAAATTCTACGGCTCTAACGTTG
ACGTACTATTTGACCTAGCGAAAAAACATAAAGACGAAGCGAAAGAATATAACATGCCGCTAGACGTTCTAATCCCACTT
GTATACGCAATGGATTACGAAATGACAGCGAAACCAGTCGACTTCTTCGTACGCCGCAGAGGCGCTGTATTCTTCAACAT
CCACTGGGTATATGAGTGGAAAGAAGCAGTAATCAACTACATGGCTGCAAAACTTGGCTGGAGCAAAGAAGAGCAAATGA
AATACACAGCTGAATTAGAGAAAGCATTAACAGACGCTGTCATTCCTGTAGATCAACAAGAGCATGCAGCTGCATTAGCG
TAA

Upstream 100 bases:

>100_bases
AATTCGGTAGGAGATTTGGAGAGACCACAACACGCTATAGAGGCGAAATCTATAGCGGAGTTTGTGGTCTCTTTTTTCGT
TATCAAAGGGAGGAATTACC

Downstream 100 bases:

>100_bases
AATAGAGAAACACCTGAAGAGAAACTCTTTAGGTGTTTTTTTATCTTGACTAAAAATAAATAAAATGTGTTACAATGATG
GTAGAGTATATAGTATGAAT

Product: glycerol-3-phosphate dehydrogenase, aerobic

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MKFSSKQRKDVLNGVNKQELDVIVIGGGITGSGIALDGATRGLSTIVFEMQDFAAGTSSRSTKLVHGGLRYLKQLEVKMV
AEVGKERAIVYENGPHVTTPEWMLLPFHTGGTFGSFSTSIGLRVYDFLAGVKRSERRKMFNREETLKKEPLVKQEGLKGG
GYYVEYRTDDARLTIEVMKEAIEHGAKAVNYAKVDGFLYKDGKVCGVRVIDLLDGEVYEVYGKKIVNAAGPWVDTLREKD
NSKKGKVLQLSKGVHLVIDQKRFPLGQAIYFDTPDKRMVFAIPRGGKTYVGTTDTFYDKDAAVPQMTTEDRTYIINAINY
MFPSVKITEKDIESSWAGVRPLIYEEGKSASEISRKDEIWTSESGLITIAGGKLTGYRKMAEMVVDYVTNLLQKEGHSAY
PKSSTKHMPISGGHVDGSKGLPAFIAKKAGEGTKYGLTTAQAEEFAKFYGSNVDVLFDLAKKHKDEAKEYNMPLDVLIPL
VYAMDYEMTAKPVDFFVRRRGAVFFNIHWVYEWKEAVINYMAAKLGWSKEEQMKYTAELEKALTDAVIPVDQQEHAAALA

Sequences:

>Translated_560_residues
MKFSSKQRKDVLNGVNKQELDVIVIGGGITGSGIALDGATRGLSTIVFEMQDFAAGTSSRSTKLVHGGLRYLKQLEVKMV
AEVGKERAIVYENGPHVTTPEWMLLPFHTGGTFGSFSTSIGLRVYDFLAGVKRSERRKMFNREETLKKEPLVKQEGLKGG
GYYVEYRTDDARLTIEVMKEAIEHGAKAVNYAKVDGFLYKDGKVCGVRVIDLLDGEVYEVYGKKIVNAAGPWVDTLREKD
NSKKGKVLQLSKGVHLVIDQKRFPLGQAIYFDTPDKRMVFAIPRGGKTYVGTTDTFYDKDAAVPQMTTEDRTYIINAINY
MFPSVKITEKDIESSWAGVRPLIYEEGKSASEISRKDEIWTSESGLITIAGGKLTGYRKMAEMVVDYVTNLLQKEGHSAY
PKSSTKHMPISGGHVDGSKGLPAFIAKKAGEGTKYGLTTAQAEEFAKFYGSNVDVLFDLAKKHKDEAKEYNMPLDVLIPL
VYAMDYEMTAKPVDFFVRRRGAVFFNIHWVYEWKEAVINYMAAKLGWSKEEQMKYTAELEKALTDAVIPVDQQEHAAALA
>Mature_560_residues
MKFSSKQRKDVLNGVNKQELDVIVIGGGITGSGIALDGATRGLSTIVFEMQDFAAGTSSRSTKLVHGGLRYLKQLEVKMV
AEVGKERAIVYENGPHVTTPEWMLLPFHTGGTFGSFSTSIGLRVYDFLAGVKRSERRKMFNREETLKKEPLVKQEGLKGG
GYYVEYRTDDARLTIEVMKEAIEHGAKAVNYAKVDGFLYKDGKVCGVRVIDLLDGEVYEVYGKKIVNAAGPWVDTLREKD
NSKKGKVLQLSKGVHLVIDQKRFPLGQAIYFDTPDKRMVFAIPRGGKTYVGTTDTFYDKDAAVPQMTTEDRTYIINAINY
MFPSVKITEKDIESSWAGVRPLIYEEGKSASEISRKDEIWTSESGLITIAGGKLTGYRKMAEMVVDYVTNLLQKEGHSAY
PKSSTKHMPISGGHVDGSKGLPAFIAKKAGEGTKYGLTTAQAEEFAKFYGSNVDVLFDLAKKHKDEAKEYNMPLDVLIPL
VYAMDYEMTAKPVDFFVRRRGAVFFNIHWVYEWKEAVINYMAAKLGWSKEEQMKYTAELEKALTDAVIPVDQQEHAAALA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=548, Percent_Identity=32.8467153284672, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI285002231, Length=548, Percent_Identity=32.8467153284672, Blast_Score=260, Evalue=2e-69,
Organism=Escherichia coli, GI2367226, Length=470, Percent_Identity=29.5744680851064, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI1788574, Length=371, Percent_Identity=26.9541778975741, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17509253, Length=560, Percent_Identity=33.2142857142857, Blast_Score=252, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI115534726, Length=547, Percent_Identity=33.0895795246801, Blast_Score=221, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6322036, Length=611, Percent_Identity=28.9689034369885, Blast_Score=216, Evalue=1e-56,
Organism=Drosophila melanogaster, GI161077125, Length=561, Percent_Identity=33.5115864527629, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24653942, Length=561, Percent_Identity=33.5115864527629, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24653944, Length=561, Percent_Identity=33.5115864527629, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI20130025, Length=561, Percent_Identity=33.5115864527629, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24586295, Length=558, Percent_Identity=28.494623655914, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI19921278, Length=550, Percent_Identity=26.5454545454545, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI45550977, Length=399, Percent_Identity=24.5614035087719, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 62443; Mature: 62443

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSSKQRKDVLNGVNKQELDVIVIGGGITGSGIALDGATRGLSTIVFEMQDFAAGTSSR
CCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCC
STKLVHGGLRYLKQLEVKMVAEVGKERAIVYENGPHVTTPEWMLLPFHTGGTFGSFSTSI
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCHHHC
GLRVYDFLAGVKRSERRKMFNREETLKKEPLVKQEGLKGGGYYVEYRTDDARLTIEVMKE
CHHHHHHHHHCHHHHHHHHHCHHHHHHHCCCHHHCCCCCCCEEEEEECCCCEEEHHHHHH
AIEHGAKAVNYAKVDGFLYKDGKVCGVRVIDLLDGEVYEVYGKKIVNAAGPWVDTLREKD
HHHHCHHHCEEEEECCEEEECCCEEEEEEEEHHCCHHHHHHHHHHHHCCCCHHHHHHHCC
NSKKGKVLQLSKGVHLVIDQKRFPLGQAIYFDTPDKRMVFAIPRGGKTYVGTTDTFYDKD
CCCCCCEEEECCCEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCCEEECCCCCCCCCC
AAVPQMTTEDRTYIINAINYMFPSVKITEKDIESSWAGVRPLIYEEGKSASEISRKDEIW
CCCCCCCCCCCEEEEEEHHHHCCCCEEEHHHHHHCCCCCCCEEEECCCCHHHHHHHHCCE
TSESGLITIAGGKLTGYRKMAEMVVDYVTNLLQKEGHSAYPKSSTKHMPISGGHVDGSKG
ECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
LPAFIAKKAGEGTKYGLTTAQAEEFAKFYGSNVDVLFDLAKKHKDEAKEYNMPLDVLIPL
CHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VYAMDYEMTAKPVDFFVRRRGAVFFNIHWVYEWKEAVINYMAAKLGWSKEEQMKYTAELE
HHHCCCCCCCCHHHHHHHCCCEEEEEEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KALTDAVIPVDQQEHAAALA
HHHHHHCCCCCCCHHHHHCC
>Mature Secondary Structure
MKFSSKQRKDVLNGVNKQELDVIVIGGGITGSGIALDGATRGLSTIVFEMQDFAAGTSSR
CCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCC
STKLVHGGLRYLKQLEVKMVAEVGKERAIVYENGPHVTTPEWMLLPFHTGGTFGSFSTSI
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCHHHC
GLRVYDFLAGVKRSERRKMFNREETLKKEPLVKQEGLKGGGYYVEYRTDDARLTIEVMKE
CHHHHHHHHHCHHHHHHHHHCHHHHHHHCCCHHHCCCCCCCEEEEEECCCCEEEHHHHHH
AIEHGAKAVNYAKVDGFLYKDGKVCGVRVIDLLDGEVYEVYGKKIVNAAGPWVDTLREKD
HHHHCHHHCEEEEECCEEEECCCEEEEEEEEHHCCHHHHHHHHHHHHCCCCHHHHHHHCC
NSKKGKVLQLSKGVHLVIDQKRFPLGQAIYFDTPDKRMVFAIPRGGKTYVGTTDTFYDKD
CCCCCCEEEECCCEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCCEEECCCCCCCCCC
AAVPQMTTEDRTYIINAINYMFPSVKITEKDIESSWAGVRPLIYEEGKSASEISRKDEIW
CCCCCCCCCCCEEEEEEHHHHCCCCEEEHHHHHHCCCCCCCEEEECCCCHHHHHHHHCCE
TSESGLITIAGGKLTGYRKMAEMVVDYVTNLLQKEGHSAYPKSSTKHMPISGGHVDGSKG
ECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
LPAFIAKKAGEGTKYGLTTAQAEEFAKFYGSNVDVLFDLAKKHKDEAKEYNMPLDVLIPL
CHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VYAMDYEMTAKPVDFFVRRRGAVFFNIHWVYEWKEAVINYMAAKLGWSKEEQMKYTAELE
HHHCCCCCCCCHHHHHHHCCCEEEEEEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KALTDAVIPVDQQEHAAALA
HHHHHHCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2127799; 9579061; 9384377; 1809833 [H]