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The map label for this gene is yvmA [H]

Identifier: 218901937

GI number: 218901937

Start: 781547

End: 782728

Strand: Reverse

Name: yvmA [H]

Synonym: BCAH820_0819

Alternate gene names: 218901937

Gene position: 782728-781547 (Counterclockwise)

Preceding gene: 218901941

Following gene: 218901919

Centisome position: 14.76

GC content: 33.59

Gene sequence:

>1182_bases
ATGAAAAAATCTAAACTAACTTTCATTTTATATGTTGTCTGTATGAGTGCCCTACTCGGTTCCTTCGCTCAAAATATTTA
CACACCTATCTTACCGATGATTCAAAATTCTTTTCACACTTCTCTTTATCTTGTAAATGTAACAGTTTCACTTTTCACAT
TTGTTCTTGCGATTATGCAGCTCATATATGGACCTTTAATTGATACAAAAGGAAGAAAGTCTGTCCTTATCCCTAGTTTA
ATTATTAGTACAATTGGTTCAATAGGATGTGCTTTTTCGGCAAACATTTATTTATTTCTCTTTTTTAGAGCTGTTCAAGC
TATAGGAATAGCGGCTATACCTGTAGTTTCAGCAACGATTATTGGTGATTTGTTTGAAGGAAAAGAACGCGGAGAAGCAA
TGAGCCTCTATCAAATGTTACTTGCTCTCGCACCTGCGATTGGTCCTCTCATAGGTGGTTATCTCGGCAGTATAAATGGC
CACTTATCCGTATTTCTGTTTTTATCTATACTTGGCATTCTCTTATTAATTATAAACACTTCACTACTTCCAGAAACAAA
ACCAACTGTAATGAAACAACCACAAACAAAAAAGAATTACTGGCTTATCTTAAAAAATAAAACTGGATCTTCTATTACAC
TTATTGGTTTCATTCAATTTTGTATTTACTTTTGCTTTCTCGTTTTTTTACCGAGCATTTTAGCAAATTCATTTCATCTA
GCTGCAAGTGAAATTGGTCTTATGTTTGTACCAATGTCTCTTTCTATTATGATAGGAAGTTATTACTACAAGTTTTTGCA
AAAACGACTCACAACAAAGCAAGCTTTATTCATTACGAGTTTCTTCAATATTATATGTGTCGTTTTATTCTCTTTCACAT
ATAGCATCAATATCCCATTCCTCATTATCGTTACATCTTTGTACGGTTTTAGTATGGGACTTTCTATGCCAACTCACACT
ACTTTATTAACAGAAGAATTCGTACAAGAACGCGCAACAGCTATCGGCATGTACAACTTCATCCGCTATCTCGGTATGGG
GACTGGACCTATTGTAGGTGGATTTCTTTTATTTAACCAAAACTACTTTTGGATTTTCTTCCTAGGTGCAATTATGTTTC
TACTTATCATTTTATACGCAATGAAAATGCTACATTTTCATGCTTTACAAAAAGCAAAATAG

Upstream 100 bases:

>100_bases
TATACCATTTTAAAACCATTTTTTCATCTTTACAAGTGAGAAAATCATGTTAAAATAAATTTAGTTTCCAAGGAAACAAA
AACACAAGGAGGTTAACAAG

Downstream 100 bases:

>100_bases
AGCCCCCGAAAGGTCGGCTCTATTTTAAACTCTTTGATCCGCAACGATATGAATATCAATATGTTTCGTCTGTCTCATAA
TTTCATTTACAATCGAACCT

Product: major facilitator family transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKKSKLTFILYVVCMSALLGSFAQNIYTPILPMIQNSFHTSLYLVNVTVSLFTFVLAIMQLIYGPLIDTKGRKSVLIPSL
IISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVSATIIGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSING
HLSVFLFLSILGILLLIINTSLLPETKPTVMKQPQTKKNYWLILKNKTGSSITLIGFIQFCIYFCFLVFLPSILANSFHL
AASEIGLMFVPMSLSIMIGSYYYKFLQKRLTTKQALFITSFFNIICVVLFSFTYSINIPFLIIVTSLYGFSMGLSMPTHT
TLLTEEFVQERATAIGMYNFIRYLGMGTGPIVGGFLLFNQNYFWIFFLGAIMFLLIILYAMKMLHFHALQKAK

Sequences:

>Translated_393_residues
MKKSKLTFILYVVCMSALLGSFAQNIYTPILPMIQNSFHTSLYLVNVTVSLFTFVLAIMQLIYGPLIDTKGRKSVLIPSL
IISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVSATIIGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSING
HLSVFLFLSILGILLLIINTSLLPETKPTVMKQPQTKKNYWLILKNKTGSSITLIGFIQFCIYFCFLVFLPSILANSFHL
AASEIGLMFVPMSLSIMIGSYYYKFLQKRLTTKQALFITSFFNIICVVLFSFTYSINIPFLIIVTSLYGFSMGLSMPTHT
TLLTEEFVQERATAIGMYNFIRYLGMGTGPIVGGFLLFNQNYFWIFFLGAIMFLLIILYAMKMLHFHALQKAK
>Mature_393_residues
MKKSKLTFILYVVCMSALLGSFAQNIYTPILPMIQNSFHTSLYLVNVTVSLFTFVLAIMQLIYGPLIDTKGRKSVLIPSL
IISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVSATIIGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSING
HLSVFLFLSILGILLLIINTSLLPETKPTVMKQPQTKKNYWLILKNKTGSSITLIGFIQFCIYFCFLVFLPSILANSFHL
AASEIGLMFVPMSLSIMIGSYYYKFLQKRLTTKQALFITSFFNIICVVLFSFTYSINIPFLIIVTSLYGFSMGLSMPTHT
TLLTEEFVQERATAIGMYNFIRYLGMGTGPIVGGFLLFNQNYFWIFFLGAIMFLLIILYAMKMLHFHALQKAK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=280, Percent_Identity=29.2857142857143, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87082312, Length=364, Percent_Identity=23.0769230769231, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788509, Length=386, Percent_Identity=23.8341968911917, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1790146, Length=183, Percent_Identity=25.1366120218579, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322071, Length=292, Percent_Identity=26.7123287671233, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324264, Length=179, Percent_Identity=29.608938547486, Blast_Score=83, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6319657, Length=164, Percent_Identity=34.1463414634146, Blast_Score=76, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6319517, Length=186, Percent_Identity=29.0322580645161, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322070, Length=309, Percent_Identity=25.8899676375405, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6325414, Length=369, Percent_Identity=20.5962059620596, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321577, Length=369, Percent_Identity=20.0542005420054, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43832; Mature: 43832

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSKLTFILYVVCMSALLGSFAQNIYTPILPMIQNSFHTSLYLVNVTVSLFTFVLAIMQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEEHHHHHHHHHHHHHHH
LIYGPLIDTKGRKSVLIPSLIISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVSATI
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSINGHLSVFLFLSILGILLLIINT
HHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SLLPETKPTVMKQPQTKKNYWLILKNKTGSSITLIGFIQFCIYFCFLVFLPSILANSFHL
CCCCCCCCHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AASEIGLMFVPMSLSIMIGSYYYKFLQKRLTTKQALFITSFFNIICVVLFSFTYSINIPF
HHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LIIVTSLYGFSMGLSMPTHTTLLTEEFVQERATAIGMYNFIRYLGMGTGPIVGGFLLFNQ
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEEC
NYFWIFFLGAIMFLLIILYAMKMLHFHALQKAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKSKLTFILYVVCMSALLGSFAQNIYTPILPMIQNSFHTSLYLVNVTVSLFTFVLAIMQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEEHHHHHHHHHHHHHHH
LIYGPLIDTKGRKSVLIPSLIISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVSATI
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSINGHLSVFLFLSILGILLLIINT
HHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SLLPETKPTVMKQPQTKKNYWLILKNKTGSSITLIGFIQFCIYFCFLVFLPSILANSFHL
CCCCCCCCHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AASEIGLMFVPMSLSIMIGSYYYKFLQKRLTTKQALFITSFFNIICVVLFSFTYSINIPF
HHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LIIVTSLYGFSMGLSMPTHTTLLTEEFVQERATAIGMYNFIRYLGMGTGPIVGGFLLFNQ
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEEC
NYFWIFFLGAIMFLLIILYAMKMLHFHALQKAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]