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The map label for this gene is arlR [H]

Identifier: 218901847

GI number: 218901847

Start: 682110

End: 682787

Strand: Reverse

Name: arlR [H]

Synonym: BCAH820_0708

Alternate gene names: 218901847

Gene position: 682787-682110 (Counterclockwise)

Preceding gene: 218901852

Following gene: 218901846

Centisome position: 12.88

GC content: 36.28

Gene sequence:

>678_bases
ATGATTGATATACTGCTCGTAGACGATGAACCGAGAATGCTTGAATTATTAACGCTTTATCTTACTCCAATTGGATATAA
CTGCATATGTGCACGATCCGGAGAAGAAGCGATTTCACATATAGAAAATCAAAACTTTAAATTTATTTTACTCGATATTA
TGATGCCAACGATGGACGGATGGGAAACGTGCAAAAAAATCCGTTCATTTAGTAACGTTCCTATTATTATGGTTACAGCT
CGTGATCAAACCATCGATGTCGTCCAAGGATTAAAACTCGGAGCGGATGATTACGTAACGAAACCTTTCCATGAAGAAGA
ACTTTTCGCAAGAATTGAAGCTGTTTTAAGGCGAACGAATCAACACGCGCAAATCCAATATCACGGCATTTTATGGGATG
AAGCAAAGCACTCCGCTTCTGTTCATAATGAAGAGCTTCTTCTTACACCAATTGAATTCTCTTTACTCGGATTATTTTTA
TGTCATGTGAACTACGTATTGAGCCGCGATCAGCTTATTGAACGAATTTGGGGATTAAATACAAATACAGAAGATAGAAC
AGTCGATTCACATATTCGTAATTTGCGTGATAAATTACGAAAAGTAAATTTCCCTATTGATAATCATTTAAAAACTGTGT
ACGGAGTTGGTTATCGATGGATTGATATCGAACATTAA

Upstream 100 bases:

>100_bases
TAATTCTGAAGAAATTATGCAGATGCATTATAATCTGCACCATTTCTTCATGATTTTGACTTACAATTTAAGTAACGATT
ATAAAGATGGAGGGCTCTCT

Downstream 100 bases:

>100_bases
GGAGCAAAACGATGAAACGAATTTCTATTCAGCTCGGATTTTATTTTTTAATTGTTACACTTTTAATCGAAAGTGTTCTA
TTTGTTTTGCTTTATTATAG

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MIDILLVDDEPRMLELLTLYLTPIGYNCICARSGEEAISHIENQNFKFILLDIMMPTMDGWETCKKIRSFSNVPIIMVTA
RDQTIDVVQGLKLGADDYVTKPFHEEELFARIEAVLRRTNQHAQIQYHGILWDEAKHSASVHNEELLLTPIEFSLLGLFL
CHVNYVLSRDQLIERIWGLNTNTEDRTVDSHIRNLRDKLRKVNFPIDNHLKTVYGVGYRWIDIEH

Sequences:

>Translated_225_residues
MIDILLVDDEPRMLELLTLYLTPIGYNCICARSGEEAISHIENQNFKFILLDIMMPTMDGWETCKKIRSFSNVPIIMVTA
RDQTIDVVQGLKLGADDYVTKPFHEEELFARIEAVLRRTNQHAQIQYHGILWDEAKHSASVHNEELLLTPIEFSLLGLFL
CHVNYVLSRDQLIERIWGLNTNTEDRTVDSHIRNLRDKLRKVNFPIDNHLKTVYGVGYRWIDIEH
>Mature_225_residues
MIDILLVDDEPRMLELLTLYLTPIGYNCICARSGEEAISHIENQNFKFILLDIMMPTMDGWETCKKIRSFSNVPIIMVTA
RDQTIDVVQGLKLGADDYVTKPFHEEELFARIEAVLRRTNQHAQIQYHGILWDEAKHSASVHNEELLLTPIEFSLLGLFL
CHVNYVLSRDQLIERIWGLNTNTEDRTVDSHIRNLRDKLRKVNFPIDNHLKTVYGVGYRWIDIEH

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=38.9140271493213, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=39.0134529147982, Blast_Score=153, Evalue=9e-39,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.9775784753363, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=38.2608695652174, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=34.2105263157895, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=33.0316742081448, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=31.651376146789, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=32.7272727272727, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=33.1838565022422, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=31.5555555555556, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=34.6666666666667, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=29.3577981651376, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=28.82096069869, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=26.2931034482759, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1790437, Length=120, Percent_Identity=36.6666666666667, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788550, Length=125, Percent_Identity=32.8, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=29.7520661157025, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789149, Length=108, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI145693157, Length=100, Percent_Identity=34, Blast_Score=61, Evalue=8e-11,
Organism=Escherichia coli, GI1788905, Length=117, Percent_Identity=31.6239316239316, Blast_Score=60, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=108, Percent_Identity=32.4074074074074, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26218; Mature: 26218

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDILLVDDEPRMLELLTLYLTPIGYNCICARSGEEAISHIENQNFKFILLDIMMPTMDG
CEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCCEEEEEEECCCCCCC
WETCKKIRSFSNVPIIMVTARDQTIDVVQGLKLGADDYVTKPFHEEELFARIEAVLRRTN
HHHHHHHHCCCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
QHAQIQYHGILWDEAKHSASVHNEELLLTPIEFSLLGLFLCHVNYVLSRDQLIERIWGLN
CCCEEEEEEEEECCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TNTEDRTVDSHIRNLRDKLRKVNFPIDNHLKTVYGVGYRWIDIEH
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECC
>Mature Secondary Structure
MIDILLVDDEPRMLELLTLYLTPIGYNCICARSGEEAISHIENQNFKFILLDIMMPTMDG
CEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHCCCCCEEEEEEECCCCCCC
WETCKKIRSFSNVPIIMVTARDQTIDVVQGLKLGADDYVTKPFHEEELFARIEAVLRRTN
HHHHHHHHCCCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
QHAQIQYHGILWDEAKHSASVHNEELLLTPIEFSLLGLFLCHVNYVLSRDQLIERIWGLN
CCCEEEEEEEEECCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TNTEDRTVDSHIRNLRDKLRKVNFPIDNHLKTVYGVGYRWIDIEH
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA